O ensino do desenho para crianças de 9 a 10 anos de idade: um estudo comparativo entre duas escolas públicas e duas escolas particulares da região central de São Paulo

Pós-graduação em Artes - IA

Um quarto de século de construtivismo como discurso pedagógico oficial da rede estadual de ensino paulista: análise de programas e documentos da Secretária de Estado da Educação no período de 1983 a 2008

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Tempo e saberes: a constituição do professor experiente em matemática

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Alceste: o heroísmo no sacrifício ou o sacrifício do heroísmo? (uma leitura da Alceste de Eurípedes)

O presente artigo tem por objetivo tentar levantar alguns problemas do texto Alceste de Eurípides, levado à cena por volta de 438 a.C. em Atenas. No estudo aqui estabelecido, tenta-se primeiramente verificar como se configura o herói no mundo grego (tendo como base os textos de Homero e os textos de Calino e TirtBu, poetas líricos); depois, verifica em que medida é possível considerar uma heroína a figura de Alceste na Alceste de Eurípides, ou seja, verifica como se confere este estatuto à mulher. Também se discute como a noção de sacrifício entra na noção de heroísmo, sobretudo na figuração heróica da mulher.

Do dramático ao épico: a presença da tragédia na Argonáutica de Apolônio de Rodes

O presente trabalho discute a relação entre o poema épico Argonáutica, de Apolônio de Rodes, e as tragédias gregas precedentes a ele. Considera-se que as tragédias, ao lado da poesia homérica, são importantes fontes para sua abordagem do mito e, subsequentemente, para a narrativa de Apolônio. Além disso, a narrativa e os recursos expressivos que o poeta utiliza são muito próximos às tragédias de Eurípides (1939) e Ésquilo, e essa relação nos ajuda a compreender melhor como um poeta alexandrino trabalha a matéria épica após o advento da tragédia clássica.

New treatment strategies for Alzheimer's disease: is there a hope?

Alzheimer's disease (AD) is a progressive and irreversible neurodegenerative disease, and corresponds to the most common cause of dementia worldwide. Although not fully understood, the pathophysiology of AD is largely represented by the neurotoxic events triggered by the beta-amyloid cascade and by cytoskeletal abnormalities subsequent to the hyperphosphorylation of microtubule-associated Tau protein in neurons. These processes lead respectively to the formation of neuritic plaques and neurofibrillary tangles, which are the pathological hallmarks of the disease. Clinical benefits of the available pharmacological treatment for AD with antidementia drugs (namely cholinesterase inhibitors and memantine) are unquestionable, although limited to a temporary, symptomatic support to cognitive and related functions. Over the past decade, substantial funding and research have been dedicated to the search and development of new pharmaceutical compounds with disease-modifying properties. The rationale of such approach is that by tackling key pathological processes in AD it may be possible to attenuate or even change its natural history. In the present review, we summarize the available evidence on the new therapeutic approaches that target amyloid and Tau pathology in AD, focusing on pharmaceutical compounds undergoing phase 2 and phase 3 randomized controlled trials.

Neuropsychiatric symptoms in the prodromal stages of dementia

Purpose of reviewTo critically discuss the neuropsychiatric symptoms in the prodromal stages of dementia in order to improve the early clinical diagnosis of cognitive and functional deterioration.Recent findingsCurrent criteria for cognitive syndrome, including Alzheimer's disease, comprise the neuropsychiatric symptoms in addition to cognitive and functional decline. Although there is growing evidence that neuropsychiatric symptoms may precede the prodromal stages of dementia, these manifestations have received less attention than traditional clinical hallmarks such as cognitive and functional deterioration. Depression, anxiety, apathy, irritability, agitation, sleep disorders, among other symptoms, have been hypothesized to represent a prodromal stage of dementia or, at least, they increase the risk for conversion from minor neurocognitive disorder to major neurocognitive disorder. Longitudinal investigations have provided increased evidence of progression to dementia in individuals with minor neurocognitive disorder when neuropsychiatric symptoms also were present.SummaryAlthough neuropsychiatric symptoms are strongly associated with a higher risk of cognitive and functional deterioration, frequently the clinician does not acknowledge these conditions as increasing the risk of dementia. When the clinician accurately diagnoses neuropsychiatric symptoms in the prodromal stage of dementia, he could early establish appropriate treatment and, may be, delay the beginning of clinical and functional deterioration.

Neurobiological Correlates of Apathy in Alzheimer's Disease and Mild Cognitive Impairment: A Critical Review

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Physical Exercise in MCI Elderly Promotes Reduction of Pro-Inflammatory Cytokines and Improvements on Cognition and BDNF Peripheral Levels

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

O mito de Medeia nas Heroides de Ovídio: epístola XII - Medeia a Jasão

This work aim briefly study the myth of Medea and Jason, making an account of the Latin poet Ovid’s approach on it in his work Heroides Epistle XII, paralleling it to the Greek poet Euripides’ tragedy Medeia

As representações de Medeia nas Metamorfoses de Ovídio e na Argonáutica de Apolônio de Rodes

This paper focuses on how the ancient roman poet Ovid’s approach on the mythical character Medea in Metamorphoses Book VII relates to the presence of the character in the Hellenistic greek epic poem Argonautica of Apollonius Rhodius, once the Greek author is known to influence the Roman. Although Ovid’s narrative goes further and focuses on events subsequent to the Argonauts travel, the relationship between the two works allows to address two aspects: the inner monologue and the anxieties of Medea which, by their turn, draw a timeline of the historical influence of Euripedes’ tragedy Medea; going through Apollonius and eventually arriving at Ovid; and the description of Medea’s magical practices and powers, used in Argonautica to protect Jason, which are widely described in Metamorphoses when she rejuvenates Aeson, the hero’s father. It is intended not only to point out aspects of character related to these topics, but primarily to address the mechanisms that can identify the direct influence of Apollonius on Ovid

Anti-dementia medications: current prescriptions in clinical practice and new agents in progress

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Caregiver report versus clinician impression: disagreements in rating neuropsychiatric symptoms in Alzheimer's disease patients

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Um conceito plural: a ἄτη na tragédia grega

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Pólis vs. Oikos: a investigação do papel feminino no drama grego

This work analyzes the consequences of the intersection between the two spheres polis and oikos. It does so by examining themes present in three plays: Medea, Agamemnon and Lysistrata. The focus of the analysis is the way in which the feminine characters react to conflicts of interests in their respective situations. To fully comprehend which values correspond to which mentioned institution, the work also necessarily investigates the socialization and functions of both genders in fifth-century Athenian society. The analysis of the feminine condition in the creation myth implies the importance of the misogynistic sense of that time, which culminated in the silencing, discrediting, and systemic repression of females. The role of women in society, instilled in all girls starting in early childhood, is to succeed in marriage and domestic permanence. This lies opposite the masculine role, which was focused outside of the family center and to environments relating to war and public life. Matrimony and family, traditional female values, were threatened when overlapping with male interests, such as unavoidable war or social ascension through a different matrimonial bond. Therefore, it is possible to affirm that the opposition evident in the definitions male vs. female indicates that, in certain contexts, the interests of each element cause the conflicts present in the chosen plays