Protocolo para ensaios físico-químicos de estabilidade de fitocosméticos

The growing demand for stable, safe and effective cosmetics has required increasingly complex studies by the scientific community and the use of more efficient techniques to determine the stability of these products. The use of active principles from the Brazilian flora has led to the development of numerous products, in the most varied pharmaceutical forms, making it, even more difficult to standardize experimental protocols to certify the stability of cosmetic preparations. While in Brazil there is no one protocol that standardizes the tests that should be carried out to determine product stability, several studies have been conducted in academic laboratories to determine the stability of specific raw materials. The rheological properties of topical use products have to be taken into account in their manufacture, storage and application. The determination of the rheological behavior of a formulation helps in evaluating the physicochemical nature of the vehicle, allowing early signs of physical instability to be detected and thus enabling quality control of the constituents, test formulations and final products. Thermal analysis has also been used to assist in the study of cosmetic stability and differential scanning calorimetry to guide the development of new products. Other tools, such as fluorimetry and laser granulometry can be used to help the study and development of both emulsified and non-emulsified systems. The aim of the present study is to develop a protocol for the investigation of the physical and chemical stability of phytocosmetics - systems containing active compounds extracted from the Brazilian biodiversity.

Ensaios biológicos para avaliação de segurança de produtos cosméticos

Despite efforts to the contrary, some cosmetic products can cause undesirable side effects in the users. These may often be due to individual factors or inappropriate use of the product. Thus, biological assays to assess the safety of a new cosmetic must precede its being placed on the market. Historically, these tests have always been carried out in vivo, in animals, since such tests can be used to evaluate many of the potential risks, such as irritation, allergy or systemic effects; but, recently, some research centers have been adopting in vitro alternatives, in order to replace the animal tests. This review emphasizes the need to employ biological assays to test the safety of cosmetic products, and reviews the main in vivo and in vitro tests used, focusing on the need to develop and use alternatives to the in vivo assays of product safety, so as to offer the consumers the maximum safety with the least possible risk, while ensuring the best conditions of use of the product.

Mutagenicidade de duas espécies do gěnero Alchornea avaliadas através de ensaios com Salmonella microssomo e teste do micronúcleo

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Análise da compacidade do solo na área urbana de Bauru/ Estado de São Paulo utilizando Ensaios de Penetração Padronizado e sísmica de refração

This study was done to determine compactness of soil strata in the urban area of Bauru, central São Paulo State using standard penetration test (SPT) and seismic refraction methods. Frequency distribution within boreholes was measured every meter to a depth of 30 meters. The geometric mean of standard penetration test values was computed every meter. A biplot graph showing the relationship of SPT with depth indicates soil stratification. In addition, five sections of seismic refraction values, which also indicate the compactness of soil strata, were obtained. A comparison of the two methods shows significant correlation between the results obtained from each.

Software de rastreamento de embarcações e plataforma eletrônica para ensaios hidrodinâmicos em túnel de vento

Pós-graduação em Engenharia Elétrica - FEIS

Estudo de uma ferramenta computacional inteligente para auxiliar a análise de ensaios de impulsos atmosféricos em transformadores de distribuição

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Estudo da atividade antioxidante de frutas tropicais exóticas sobre espécies reativas de oxigênio de importância biológica em ensaios modelos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Ensaios comparativos de mistura asfáltica pré-misturado a frio com adição de borracha de pneu

Pós-graduação em Ciência e Tecnologia de Materiais - FC

Ensaios sobre computação e informação quânticas: fundamentação e simulações sobre o efeito da entropia

Pós-graduação em Ciência da Computação - IBILCE

Ensaios sobre o investimento direto externo: os casos das empresas espanholas e coreanas

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Ensaios de tratamento de efluentes de indústria de chapa dura de fibra de madeira

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Atributos físicos e mecânicos do solo avaliados por processamento digital de imagem e ensaios de rotina

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Desenvolvimento de programa computacional para delineamento em blocos completos casualizados com respostas multidimensionais e sua aplicação em ensaios agronômicos

Pós-graduação em Agronomia (Energia na Agricultura) - FCA

Estudo da reação álcali-agregado na tomada d'água da UHE Jaguari por meio de ensaios laboratoriais

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

A América Latina, de Manoel Bomfim, e Ariel, de José Enrique Rodó: ensaios de interpretação latino-americana

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)