Potencial antioxidante, óleo essencial e atividade antifúngica de plantas de jambu (Spilanthes oleracea), cultivadas sob adubação orgânica e convencional e processamento mínimo de nectarina (Prunus persica var. nectarina): conservação de suas qualidades e propriedades bioativas

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Potencial de remineralização do cálcio e fosfato: revisão de literatura e estudo laboratorial

Pós-graduação em Ciência Odontólogica - FOA

Potencial de utilização de nematóides entomopatogênicos (Nematoda: Rhabditida) no controle do cupim de montículo (Cornitermes cumulans Kollar)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Estudo do potencial de diferenciação de células-tronco mesenquimais equinas oriundas do sangue da medula óssea cultivadas sobre um filme multicamadas de biopolímeros: quitosna, HA e CMC

Pós-graduação em Biologia Geral e Aplicada - IBB

Avaliação do potencial efeito cicatrizante gástrico e antiartrítico da mangiferina, uma xantona glicosilada da Mangifera indica

Rheumatoid arthritis (RA) is a chronic illness with great potential to cause comorbidities resulting from cumulative inflammatory activities, and it contributes with the increase of disabilities and death of patients. It affects 1 to 2% of world population and usually occurs between 30 and 50 years of age. Among existing therapeutic options for the disease non-steroidal anti-inflammatory drugs (NSAIDs) still play an important part in the treatment, being widely used by patients to relieve pain and stiffness. However, this class of drugs causes many adverse gastrointestinal effects, such as dyspepsia, heartburn, nausea and vomit, and its use is one of the most common causes of peptic ulcers. Mangiferin (a glicosilated xanthone extracted mainly from the bark of Mangifera indica L.) is the main compound of an aqueous extract made from the bark stem of the mango tree. Previous studies conducted by our research group prove the anti-inflammatory action of mangiferin on an animal model of periodontitis, and its gastroprotective action has been described before. Considering these informations this study evaluated mangiferin’s potential on the treatment of RA and on gastric ulcer healing in animal models, and analyzed toxicity parameters to assure efficacy and safety of the compound as potential new drug for the treatment of the disease. RA was induced in rats by subcutaneous injection of bovine collagen and Freund’s complete adjuvant. This method presented low incidence of RA in rats, but we were able to induce the disease in 60 to 70% of the animals. Due to the wide use of NSAIDs and its potential to cause peptic ulcers, we induced gastric ulcer on arthritic rats to analyze mangiferin’s gastric healing effect. After 14 days of treatment we noticed small increase of the lesion area of animals treated with mangiferin or ibuprofen, when compared to the animals... (Complete abstract click electronic access below)

Análise comparativa entre a produção de biogás em aterro controlado e variações no potencial elétrico natural por meio de perfilagem geofísica

This work aims to analyze data from a Natural Electric Potential landfill type ditch located in Cordeirópolis (SP). The procedure measures initially involved the assembly and installation of an apparatus cables, sensors and drain geophysical measurements and flow rate of biogas in a ditch later filled by solid waste. Biogas is a product of degradation of organic matter in waste by the action of microorganisms in an anaerobic environment. Its features high methane content in the gas potentially usable as fuel in energy generation systems or steam. The study area is characterized by clayey soil composition change from the diabase sill correlated to the event Serra Geral Formation siltstones overlapping Tatuí with groundwater level site around 50m. The cables were installed vertically in parallel with drain gas manifold, which allowed the collection of data by the technique geophysical logging every 15 days over a period of eight months. For data analysis we used four parameters in the study, the closing time of the ditch, natural electric potential, the flow velocity of biogas and rain. With the tabulated data plots were constructed for each collection day showing values in the range of the cable is in contact with waste (200 cm - 400 cm) and range of the cable in contact with the soil (600 cm - 800 cm). Subsequently graphs were generated with the period of eight months to analyze the data tabulated. A statistical correlation data, which show the influence of rainfall on the production of biogas. The results were satisfactory and demonstrated the feasibility of the research method in studies for the feasibility analysis for the capture of biogas energy

Expressão gênica e potencial de desenvolvimento in vitro dos complexos cúmulos-oócitos ovinos tratados com roscovitina

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Endodontics pastes formulated with copaiba oil: action on oral microbiota and dentin bridge formation in dogs

This study analysed the effect of pastes formulated with calcium hydroxide P.A. and different vehicles (saline solution - paste A and Copaifera langsdorffii Desfon oil - paste B) on oral microorganisms and dentin bridge formation in dogs. The antimicrobial action of the pastes and their components was analysed by the minimum inhibitory concentration in agar gel technique. The components were diluted and tested on fifteen standard strains of microorganisms associated with endodontic diseases. The microorganisms were cultivated and after incubation data was analysed using One-Way ANOVA and Turkey's test (P≤0.05). Four superior incisors of ten animals were used to evaluate dentin bridge formation. Two incisors were capped with paste A (GA) and two with paste B (GB). After 90 days, the teeth were extracted for histological analysis and the degree of dentin bridge formation evaluated. Data was analysed by the Kruskal-Wallis test (P<0.05). The pastes and their components were classified in the following decreasing order of antimicrobial action: calcium hydroxide P.A., paste A, paste B and Copaifera langsdorffii Desfon oil. Calcium hydroxide P.A. showed significantly higher antimicrobial action than the pastes or their vehicles. No significant difference was observed between the two pastes in dentin bridge formation. Based on the microorganisms studied, it can be concluded that the pastes analysed showed similar antimicrobial potential but differed significantly from their individual components. No significant difference was observed in dentin bridge formation between the different pastes tested.

Estudo do potencial de degradação do herbicida diuron e seus metabólitos por bactérias isoladas de solo de canavial

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Avaliação do potencial de degradação do herbicida diuron por fungos isolados de solo de canavial e suas tolerâncias aos metabólitos gerados

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Influence of soil water potential in the action of herbicides on goosegrass (Eleusine indica (L) Gaertn)

Currently, the use of herbicides is essential in a practical and common in agricultural areas, but efficiency of these herbicides can be compromised when applied on plants that thrive in water deficit conditions, due to low uptake and translocation of the product. Therefore, the aim of this study was to compare the efficiency of control ACCase inhibiting herbicides applied post-emergence in plants of Eleusine indica under different soil water contents. The experiment was conducted in a greenhouse and the experimental design was completely randomized design with four replications, consisting of a 9x4 factorial, with the combination of three soil water potentials (-0.03, -0.07 and -1.5 MPa) three herbicides (fluazifop-p -butyl, haloxyfop-methyl and sethoxydim + oil) and four doses (0, 25, 50, and 100 % of the recommended dose). Herbicide application was made in plants in vegetative stage 2-3 tillers. The soil water potential was initiated in the development stage of two leaves, and the water was supplemented until the soil reaches the potential of -0.01 MPa, when it came to minimum pre-determined for each water management. The physiological parameters evaluated were: photosynthetic rate, stomatal conductance, transpiration leaf temperature and plant dry mass. The visual assessments of phytotoxicity were performed at 7 and 14 days after application. The herbicides behaved in different ways according to the used water management. In severe water stress conditions (soil moisture at 8%) only fluazifop-p-butyl herbicide achieved satisfactory control (> 90%) in E. indica plants.

Espectro de gotas e potencial de deriva de caldas contendo o herbicida 2,4-d amina em misturas em tanque

Pós-graduação em Agronomia (Energia na Agricultura) - FCA

Caracterização do potencial inseticida e capacidade antioxidante de Spathodea campanulata (Bignoniaceae)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)