19 resultados para êxodo
Resumo:
The process of urbanization that happened in Brazil during the twentieth century led to processes of structuring and re-organization of space, besides the emergence of many urban problems. Industrialization and urbanization are some of the main causes that could be cited as consequences of this process. As a result of the steep rise of cities, the transport systems became fundamental in boosting flows (immaterial) and the mobility of people and stuff (materials) in the territory. The urban model created for the city of São Paulo in the 1930s was repeated over the years in the medium-sized cities, being repeated the same problems that occurred in the metropolis. In this context our work fits in analyzing the changes occurring in the urban area of São José do Rio Preto - SP, from his relationship with the public transportation system in the face of intra-urban spatial configuration of the city. Transport, while it is recognized by authors as being really important for the analysis and intra-urban spatial configuration, has been little analyzed as the object of study by a geographer, and so, our work has more value
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Pós-graduação em Engenharia Civil - FEIS
Resumo:
The equilibrium interaction of doxorubicin and its N-acetyl derivative with a series of purine-pyrimidine alternating polydeoxynucleotides has been studied through spectrofluorometry to assess the relevance of the electrostatic contribution to DNA intercalation. The results have shown that: (a) the suppression of the positive charge on the aminosugar has: (I) a profound negative effect on the free energy of intercalation, as expected, and (II) a negligible influence on the base specificity, which supports the notion of an essentially electrostatic effect of N-acetylation on intercalation; (b) a reasonably good accord with the demands of a polyelectrolytic model, due to Friedman and Manning, is found.
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Pós-graduação em Geografia - FCT