403 resultados para Terapia celular


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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Pós-graduação em Enfermagem - FMB

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Pós-graduação em Microbiologia - IBILCE

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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The oral cancer model in hamsters shows many simílarities with developmental oral cancer in humans. The proliferating capacity is one the most characteristics of neoplásica ce/Is and detection of these ce/Is allow us, throughout of its counting, to achieve an estimated tumour growing index, with a consequent repercussion about prognostic and in the treatment of those lesions. 40 golden Syrian hamsters, both genders, aged between two to six mouth and weight 150g in average were used. The left síde of tangue of each animal was painted for eight consecutive weeks, with a solution of DMBA. Tongues were removed, fixed in 10% buffered fonnal solution. The histological slides were stained by AgNOR technique and by PCNA and β-catenin immunohistochemical antibodies. Statistical analyzes were performed by ANOVA one-way test and Tukey test. We may conclude that an association between AgNOR and PCNA might indicate the higher proliferating activity of the analyzed celIs. The experimental carcinogenesis model in hamster tongue is an available methodology for immunohistochemistry study. And finally, PCNA and β-catenin immunohistochemical antibodies may be used to analyze possible premalignant areas in oral leukoplakia

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Unilateral Neglect Syndrome is one of the consequences of cerebral vascular accident (CVA) generally following right parietal lobe lesion, leading to the impairment of perceptive visual, spatial and attention functions. The patient affected does not realize the environmental stimuli on the contralesional hemibody. Occupational therapy plays an important role in caring for this patient, seeking the recovery of perception, attention and social engagement. This study aimed to describe and evaluate the results of occupational therapy intervention and treatment in a single Unilateral Neglect Syndrome post CVA patient. Data were obtained from a survey of the patient’s medical records and interviews of his therapist and caretaker. The analysis of the patient’s medical records and his therapist’s report showed that the patient responded satisfactorily to treatment, presenting a decrease of the left unilateral neglect at the end of the study period. The favorable outcome of the patient outlined the relevance of evaluating the effects of Occupational Therapy interventions for clinical unilateral neglect syndrome.

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The way one conceives disabled people seems to influence the actions directed toward them. Occupational therapists constitute a part of health professionals that direct their actions based on a comprehensive view of disability. The aim of this study was to identify and analyze the conception of disability from the standpoint of occupational therapists. Fifteen university teachers of Occupational Therapy undergraduate courses participated in this study: seven from public universities and eight from private institutions, located in mid-sized municipalities in the state of São Paulo. The data were collected by means of a scale denominated “Escala de Avaliação da Concepção de Deficiência” (Rating Scale for Conception of Disability). The results show that the subjects tend to follow interactional, social conceptions of disability. This study yields contributions to understand the conception of disability held by teachers of Occupational Therapy. This conception certainly guides their teaching performance and affects the training of future professionals.

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The inclusive school consists of a school that thoroughly attends the diversity and, therefore, students with special educational needs, including the ones with physical dysfunction. The objective of this study was to identify the difficulties of a teacher in the process of school inclusion of the student with physical dysfunction in order to adapt learning resources, having adequate school furniture and to guide the teacher in specific situations. A teacher of early childhood education participated in this study. For data collection two half-structuralized interviews were used. The first obtained information concerning the teacher’s difficulties due to the motor aspects of the student with difficulty to access the curriculum. The second interview gathered information about the teacher’s perception of the partnership between the occupational therapist and the teacher in the perspective of the inclusive education. The data analysis of the first interview and the student case-study allowed elaborating occupational therapy strategies to minimize these difficulties.After elaborating the strategies, a second interview was performed. The data of this interview showed that based on the analysis and adequacy of the interaction between a person’s functional demands, the task and the environment, make it possible for the student to overcome satisfactorily the inherent challenges of the educational context, and detached the importance of the partnership of the teacher and occupational therapist in the whole process. It concludes that the pupil incapacity would not have manifested if there was an adequate environment to receive him.

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A Política Nacional de Atenção Oncológica almeja o acesso e atendimento integral além de uma maior efetividade e efi ciência no controle do câncer. Assim, diversas ações, serviços e profi ssionais são exigidos para dar a assistência necessária. A respeito da atuação da Terapia Ocupacional, nota-se que a profi ssão não é especifi cada, e não tem a atuação regulamentada. Sendo assim, o objetivo principal do presente estudo foi identifi car a inserção, atuação e ampliação do campo de trabalho da Terapia Ocupacional no Estado de São Paulo para a área oncológica em contexto hospitalar, tomando por base as Políticas Públicas de Atenção Oncológica. Visou também identifi car os Centros de Assistência de Alta Complexidade em Oncologia do Estado de São Paulo que possuem o terapeuta ocupacional como parte da equipe. Para tanto, foi realizada: identifi cação dos Centros de Alta Complexidade em Oncologia do Estado de São Paulo cadastrados no Cadastro Nacional de Estabelecimentos de Saúde, por meio de dados fornecidos pelo INCA e do site ofi cial do Ministério da Saúde; mapeamento da inserção do terapeuta ocupacional nesses locais e aplicação de questionário aos profi ssionais, para caracterizar os serviços e ações desenvolvidas pela Terapia Ocupacional em oncologia. O estudo do tipo qualitativo descritivo constatou a existência de diferentes possibilidades assistenciais em oncologia, tendo em vista as demandas e organização dos hospitais. Quanto à inserção e ampliação do campo de trabalho, verifi cou-se que nem todos os CACONs contam com os serviços e ações da Terapia Ocupacional, o que sugere que ainda não há efetivamente a incorporação desse profi ssional nas equipes multiprofi ssionais desses centros.

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Individuals with temporomandibular disorders (TMD) often have signs and symptoms such as intra-articular pain, muscle spasm, neck pain radiating from others who interfere with this balance. Over time can lead to postural changes and correction of the cervical spine, anterior head and shoulder asymmetry. The aim was to verify the effects of manual therapy on posture in subjects with TMD. Materials and methods: 30 volunteers (mean: 21.43± SD:1.43) of both sexes who had TMD classified according to axis I of the Research Diagnostic Criteria participated in this study. These were photographed in the anterior frontal and sagittal planes for analysis of the following angles (acromion clavicular joint, sternoclavicular joint, orbicular external, corners of the mouthand and protruding head). After, the volunteers were divided into groups ATM (manual therapy in the treatment of temporomandibular joint), Cervical (manual therapy in the treatment of cervical joint) and Control. The Kolmogokov-Smirnov test, followed by ANOVA, considering a significance level of 5% was used. Results: Groups ATM, Cervical and Control were considered homogeneous with respect to the values of the angles measured. These also showed no significant difference between the 1st, 5th and 10th sessions, so the manual therapy techniques applied to the TMJ and Cervical groups were not sufficient to change postural alignment. Conclusion: The postural alignment, the TMD patients evaluated in this study did not change after attending the sessions proposals with manual therapy techniques in the cervical and TMJ.

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Introduction: The low back pain are a problema of health. Objective: to evaluate the effects of the Maitland´s manipulation in pain, fl exibility, functional capacity and quality of life of the patients with chronic low back pain. Method: Sxteen subjects, of both genders, with the age from 23-68 years old (48.69,± 11.61 years old) were evaluated by test sit and reach (TSA), Visual Analogue Scale (VAS) and answered the questionnaires of the quality of life Medical Outcomes Study 36- Item Short-Form Health Survey (SF-36) and the Roland-Morris Disability functional incapacity (RMDQ). The treatment was carried out twice a week, totaling 10 sessions. Each session lasted 30 minutes and consisted by Maitland´s techniques, applied as the symptoms evaluated at the beginning of each session. After 10 session, the subjects were re-evaluated. The data obtained in the assessments concerning the TSA and VAS were analyzed by Student t test, the data relating to the questionnaire were analyzed using the Wilcoxon non-parametric statistics test. For the interpretation was used signifi cance level of 5% (p≤0,05). Results: A signifi cant improvement was in the intensity of pain, disability, fl exibility and quality of life. Conclusion: The Maitland´s therapy showed effective, which suggests be an appropriate strategy for intervention for patients with chronic low back pain.

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Evaluate the effects of a modifi ed ConstraintInduced Therapy intervention protocol regarding movement quality and frequency of use of the affected upper extremity on children with hemiplegic cerebral palsy. Longitudinal study of a single case, performed with a four year old submitted to intervention during three hours daily, for ten days, restricting the non-affected upper extremity for eight hours daily. Data were collected using the Pediatric Upper Extremity Motor Activity Log and analyzed using the arithmetic mean. Signifi cant improvement in quality of movement and frequency of use of the upper limb from pre to post-intervention were noted, maintaining the result in later data collection, besides the acquisition of functional motor skills. The modifi ed constraint-induced movement therapy protocol of this study was effective in treating the child with hemiplegic cerebral palsy, the results may be useful for professionals working with this clientele, assisting them in the intervention process.