317 resultados para Proteínas celulares Teses
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Coordenao de Aperfeioamento de Pessoal de Nvel Superior (CAPES)
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Nas ltimas dcadas, o mundo tem vivenciado um grande aumento da prevalncia de obesidade. Entre os fatores que levam a esta condio, esto o sedentarismo e o consumo de alimentos altamente calricos. A obesidade considerada uma condio de inflamao crnica de baixo grau, que leva ao desenvolvimento de doenas crnicas no transmissveis, como diabetes mellitus tipo 2 e hipertenso arterial. O consumo de compostos biologicamente ativos, dentre eles os flavonoides ctricos, tem mostrado ter papel importante no controle da inflamao, e de alteraes no metabolismo decorrentes do excesso de peso e gordura corporal. Neste trabalho foram revisados trabalhos sobre flavonoides ctricos e seu papel na inflamao relacionada obesidade, assim como nas alteraes decorrentes desse processo. Os artigos foram divididos em dois grupos: suplementao com extratos de flavonoides e com flavonoides isolados. Nos dois grupos os trabalhos demonstraram o papel benfico dos flavonoides ctricos no metabolismo lipdico, e diminuindo marcadores biolgicos de inflamao, como proteínas e enzimas, tanto nos modelos experimentais quanto em linhagens celulares de adipcitos e hepatcitos. A reduo de massa corprea tambm foi observada em ratos e camundongos suplementados com os flavonoides ctricos. Entretanto, no que concerne obesidade e diminuio da massa corprea em humanos, os trabalhos so inconclusivos at o momento.
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Ps-graduao em Biotecnologia - IQ
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Conselho Nacional de Desenvolvimento Cientfico e Tecnolgico (CNPq)
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This paper aims to base the thesis that the varied currents of the post-modern thought, in so far as have recourse to relativism to a greater or lesser degree, contribute to the legitimation of the religious education in public schools and, in a broader aspect, the religion in the public spaces. The methodological resource used to demonstrate the link between post-modern thought and religious education is the analysis at the historical and dialectical materialism perspective of publications produced to increase teachers on this discipline that is, in compliance with the Constitution, optional for students and mandatory for public elementary schools. The subject of this analysis is the learning content and has as prime concern to highlight the discourse of legitimation recurrent in authors when it is explicit in itself and explicit when it does not. The religious education in public schools as object of study allows us to understand the relationship between the post-modern thought, with its hegemony space within the human sciences and contextualized in the neoliberal economic environment, and the learning to learn pedagogies currently hegemonic in the educational landscape. We intend to contribute to the legal debate on laity, the philosophical debate on post-modernism and especially to the debate on the pedagogical theories in the educational fundaments.
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The present article aims to elaborate an objective analytical panel, initially from the 1920- 1930 when Luiz Igncio Romeiro de Anhaia Mello, cathedratic in the urban question, started to quote a series of authors and American plans as references to their reflections, mainly when the point was the verticalization or not at So Paulo City. From a broad bibliographic research with the systematization of the register from the debate between Anhaia Mello, this article intends to point out how the transposition of the urbanistic conceptions to the academic environment happened and, at the same time, the legal normatization of the So Paulo City that resulted in the creation of a draft of the regulations for use and occupation of the soil. The systematizations and analysis were based in a broad reading of the bibliography and documental sources that refer to the proposed theme. The books of the library of FAU-USP, specifically the one from SAGMACS Sociedade de Anlises Grficas e Mecanogrficas Aplicadas aos Complexos Sociais ( Society of Graphical Mechanical-Graphic Analysis Applied to Social Complexes) -, aiming to select papers and the collection of Anhaia Mellos family, so that a reconstruction of the intellectual and professional journey of the Urbanism Professor. The systematization of the collected data and posterior comparison with the bibliographical study was fundamental for the reconstruction of the reflection of Anhaia Mello about the ways of the urban streets and roads at Sao Paulo City should be lead to on the middle of the XX century having as a guideline the debate between Anhaia Mello very common on the 1950s for less important countries when dealing with the organization of the size of industrial metropolis. It was possible to identify the crystallization of one urbanistic proposal for the city: the from Anhaia Mello, that bet on the reversion of the metropolitan cycle by stopping the urban growth by the application of the theoretical conception of the garden city.
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The aim of this study was to evaluate the clinical, tomographic, and histological similarity within the use of HA+-TCP (Boneceramic) alone or associated with enamel matrix derived (EMD) proteins in sinus lifting procedures with subsequent dental implant placement. We selected two patients with residual bony ridges between 3 mm and 5 mm in height in need of bone grafts. Six months later, eight implants were installed (two implants at each site). Biopsies were made, and the tissue was processed and stained with HE solution. Tomographic evaluation showed bone height gain up to 10.0 mm on average. Histology showed new bone formation for both groups, with similar bone density and trabecular interconnectivity. It can be concluded that the HA+-TCP graft isolated or associated to EMD provided bone height gain in sinus lifting procedures, with similar clinical, tomographic and histological characteristics.
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Osseointegration involves a cascade of biological events, which can be accelerated by modifying the micro and/or nanometric topography of dental implant surfaces. Considering that different treatment types modify the titanium surface giving it a more pronounced rough topography, and physicochemical changes that appear to positively influence the osseointegration process, a literature review was made on the main types of surface treatments and their influence on the biological and cellular aspects of osseointegration, with publications dating from 1969 until the present moment. Although the precise role of the implant surface on the osseointegration of dental implants is not completely clear, the specific effects of implant surface on bone regeneration, initial kinetics, and evolution of mechanical properties have shown to be quite promising. Thus, based on dental implant surface modifications, osseointegration can be defined as a process by which rigid asymptomatic fixation of an alloplastic material can be achieved and kept in close contact with bone tissue, being resistant to early and late functional loads. This process can be modulated by an appropriate treatment of the alloplastic material surface.
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Fundao de Amparo Pesquisa do Estado de So Paulo (FAPESP)
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Ps-graduao em Pesquisa e Desenvolvimento (Biotecnologia Mdica) - FMB
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Ps-graduao em Agronomia (Horticultura) - FCA
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Coordenao de Aperfeioamento de Pessoal de Nvel Superior (CAPES)
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Fundao de Amparo Pesquisa do Estado de So Paulo (FAPESP)
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Coordenao de Aperfeioamento de Pessoal de Nvel Superior (CAPES)
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Fundao de Amparo Pesquisa do Estado de So Paulo (FAPESP)