Aquisição de densidade mineral óssea e prática de modalidades esportivas de combate em jovens

Pós-graduação em Ciências da Motricidade - IBRC

Síntese estendida: uma investigação histórico-filosófica

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Utilização de lama vermelha para oxidação eletrolítica assistida por plasma de liga de alumínio

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Mandibular cortical bone evaluation on cone beam computed tomography images of patients with bisphosphonate related osteonecrosis of the jaws

Objectives The objective of this study was to develop a technique for detecting cortical bone dimensional changes in patients with bisphosphonate-related osteonecrosis of the jaw (BRONJ). Study Design Subjects with BRONJ who had cone-beam computed tomography imaging were selected, with age- and gender-matched controls. Mandibular cortical bone measurements to detect bisphosphonate-related cortical bone changes were made inferior to mental foramen, in 3 different ways: within a fixed sized rectangle, in a rectangle varying with the cortical height, and a ratio between area and height. Results Twelve BRONJ cases and 66 controls were evaluated. The cortical bone measurements were significantly higher in cases than controls for all 3 techniques. The bone measurements were strongly associated with BRONJ case status (odds ratio 3.36-7.84). The inter-rater reliability coefficients were high for all techniques (0.71-0.90). Conclusions Mandibular cortical bone measurement is a potentially useful tool in the detection of bone dimensional changes caused by bisphosphonates. Long-term administration of bisphosphonates (BPs) affects bone quality and metabolism following accumulation in bone.1 Since the first cases of bisphosphonate-related osteonecrosis of the jaw (BRONJ) were published in 2003,2 there has been a search for factors that can predict the onset of the condition. Oral and intravenous BPs reduce bone resorption, increase mineral content of bone, and alter bony architecture.3, 4, 5 and 6 Previous studies have demonstrated these changes both radiographically and following histologic analysis.1, 3, 7, 8, 9 and 10 The BP-related jaw changes may present radiological features, such as thickening of lamina dura and cortical borders, diffuse sclerosis, and narrowing of the mandibular canal3 and 11; however, oral radiographs of patients taking BPs do not consistently show radiographic changes to the jaws.11 and 12 The challenge is to find imaging tools that could improve the detection of changes in the bone associated with BP use. Various skeletal radiographic features associated with BRONJ in conventional periapical and panoramic radiographs, computed tomography, magnetic resonance imaging, and nuclear bone scanning have been described.3, 8, 9, 10 and 11 There has also been a search for BP-related quantitative methods for the evaluation of radiographic images, to avoid observer subjectivity in interpretation. Factors thought to be important include trabecular and cortical structure, and bone mineralization.4 Consequently, measurable bone data have been reported in subjects taking BPs through many techniques, including bone density, architecture, and cortical bone thickness.1, 4, 7 and 13 Trabecular microarchitecture of postmenopausal women has been evaluated with noninvasive techniques, such as high-resolution magnetic resonance images showing less deterioration of the bone 1 year after initiation of oral BP therapy.4 A decrease in bone turnover and a trend for an increase in the bone wall thickness has been detected by histomorphometry in subjects taking BPs.1 Alterations in the cortical structure of the second metacarpal have been detected in digital x-ray radiogrammetry of postmenopausal women treated with BPs.7 Mandibular cortical width may be measured on dental panoramic radiographs, and it has been suggested as a screening tool for referring patients for bone densitometry for osteoporosis investigation.14 and 15 Inhibition of the intracortical bone remodeling in the mandible of mice taking BPs has been reported.16 Thus, imaging evaluation of the mandibular cortical bone could be a biologically plausible way to detect BP bone alterations. Computed tomography can assess both cortical and trabecular bone characteristics. Cone-beam computed tomography (CBCT) can provide 3-dimensional information, while using lower doses and costing less than conventional CT. The CBCT images have been studied as a tool for the measurement of trabecular bone in patients with BRONJ.13 Therefore, cortical bone measurements on CBCT of the jaws might also help to understand bone changes in patients with BRONJ. There is no standard in quantifying dimensional changes of mandibular cortical bone. We explored several different approaches to take into consideration possible changes in length, area, and volume. These led to the 3 techniques developed in this study. This article reports a matched case-control study in which mandibular cortical bone was measured on CBCT images of subjects with BRONJ and controls. The aim of the study was to explore the usefulness of 3 techniques for detecting mandibular cortical bone dimensional changes caused by BP.

Macromineral requirements in male and female Saanen goats

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Evasão no cursinho pré-vestibular da FCA/UNESP: a interpretação do aluno evadido

The popular cram schools are voluntary initiatives aimed at people who are not able to afford the cost of private cram schools. The FCA popular cram school integrates a large project from UNESP, which has 30 cram school distributed throughout Sao Paulo State and located in different University units. Among the problems found in popular cram schools, school evasion, characterized when the student quits the course and is very common in this context. Thus, the aim of this work was to identify the profile of the drop out student from the FCA cram school as well as to know the reasons that led them to leave. The survey was conducted in two phases: 1) students´ profile when entering the cram school, through a structured questionnaire, 2) semi-structured interviews by telephone with all the drop out students, trying to identify the reasons that led them to abandon the course. The statistical analysis used was descriptive. Among the reasons that led them to leave, it was found that 65% of the students attributed this attitude to external factors as opposed to 35% who put the internal factors as the decisive reason of their departure. Some of the factors that could be attest for the FCA cram school evasion are: primarily, the heterogeneity of students and their need to work in order to support themselves and their family; students lack of motivation about a long-term success; lack of family encouragement; the difficulty of the student to establish significant personal links with cram school staff and the fact that the professors are mostly undergraduate students from different courses in different areas, with little didactic-pedagogic preparation and inability to work with students' heterogeneity.

Construção e calibração de um inclinômetro para uso em tratores agrícolas como instrumento de segurança

The tractors are the main potency source, for the traction of tillage equipments and their use are increasing more and more in Brazilian agriculture. In spite of the great technological progress the increase of the number of agricultural tractors brought positive aspects and some negative, among these last ones it stands out the appearance of a new source of work accidents, which importance is given by the physical damages caused to the operator. Therefore the objective of this work was to project and develop an inclinometer, which indicates the inclination of the land, as safety sensor for agricultural tractors to avoid lateral hollovers, through a resonant sign, for the operator and the machine preservation. The built and evaluated inclinometer showed to be efficient for inclination indication of different areas during field operations with agricultural tractors, small angle oscillation and enough answer time to help operators to take decisions in imminence situation of lateral machine hollovers.

Evaluation of discomfort in manual activities using hand mapping: the influence of age

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Nos limites do Jequitinhonha e Mucuri (MG): políticas públicas direcionadas ao espaço rural

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Sobrevivência de Xanthomonas campestris pv. campestris no solo, no filoplano e na rizosfera de plantas daninhas

Pós-graduação em Agronomia (Proteção de Plantas) - FCA

Suscetibilidade magnética e análise de incertezas em mapeamento de solos

Pós-graduação em Agronomia (Produção Vegetal) - FCAV

Humanização da saúde: impacto de estratégias lúdicas e anímicas no estado de humor de trabalhadores do SUS

Humanization is a decisive factor for the positive conditions in the work environment related to the health sector, however, few initiatives take into consideration this aspect in different areas of knowledge, including the field of Human Kinetics. Thus, this study, which has a qualitative nature, aimed to identify the mood of employees from Sistema Únicos de Saúde - SUS, using evidences based on experiences of a playful and animistic activities. The study was conducted through bibliographical and exploratory research, using as a tool two-phase data collection the Brunel Questionnaire (BRUMS). Part of this study included an international sample compose of SUS participants from Araras city, having as criteria employees associated with SUS longer than one year. Participants experienced an animistic and recreational activities program and the instrument was applied before and after these experiences. Data was descriptively analyzed through the Thematic Content Analysis Technique. The results showed that the recreational and animistic activities can positively improve the mood of workers in the health sector, indicating the importance of developing new humanization strategies in health ambit. This study suggests new actions in public policy, able to encourage longer or even continuous interventions in the daily journey of health workers

Nutritional and metabolic risk factors for insulin resistance in adults

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Avaliação das ações de alimentação e nutrição na atenção primária a saúde no estado de São Paulo

Pós-graduação em Alimentos e Nutrição - FCFAR

Ambiente web de suporte à transcrição fonética automática de lemas em verbetes de dicionários do português do Brasil

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)