347 resultados para Sistema renina-angiotensina - Efeitos de drogas


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Research has investigated the best nitrogen rate for maize under the most diverse types of soil management. The aim of this study was to evaluate the influence of cover crops, soil management and topdressed N rates on the dry matter production, nutritional status, plant lodging, plant height and first-ear insertion of maize. Field experiments were carried out in Selvíria, Mato Grosso do Sul State, Brazil, in the growing seasons of 2009/2010 and 2010/2011, on a clayey Rhodic Haplustox (20º 20' S and 51º 24' W, at 340 m asl). Thirty-six treatments were established with four replications, in a randomized blocks design, to test combinations of cover crops (millet, Crotalaria juncea and millet + Crotalaria juncea), soil management (tillage with chisel plow + lightweight disking, heavy disking + lightweight disking, and no-tillage system) and N rates (0, 60, 90 e 120 kg ha-1 - urea as source). The maize hybrid DKB 350 YG® was used and topdressing N applied at stage V5 (fifth expanded leaf). Previously grown sunn hemp and millet + sunn hemp resulted in a higher shoot dry matter, P leaf content and total N, P and K uptake. In the no-tillage system, the initial and final population and shoot dry were highest, and first-ear insertion and plant height lower. The application of 120 kg ha-1 topdressed N increased the P leaf content, N and P in the entire plant, shoot dry matter, total N, P and K uptake, plant height, and the first-ear insertion of maize.

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The hemodynamic effects of total intravenous anesthesia with propofol or propofol in combination with lidocaine were investigated in 12 dogs. In the P group (n=6), the dogs received a loading dose (LD) of 6mg kg-1 of propofol followed by a constant rate infusion (CRI) of 1.25mg kg-1 min-1. In the PL group (n=6), dogs received a LD of 6mg kg-1 of propofol and 1.5mg kg-1 of lidocaine followed by CRIs of 1.0mg kg-1 min-1 and 0.25mg kg-1 min-1 of propofol and lidocaine, respectively. The animals were instrumented for measurement of hemodynamic variables and bispectral index (BIS), recorded at 75, 90, 105 and 120 minutes during anesthesia. Cardiac index, stroke index, systolic, diastolic and mean arterial blood pressures were lower in the P group compared to the PL group (P<0.05). There were no significant differences between groups in heart rate, systemic vascular resistance index and BIS. Plasma concentrations of propofol were lower in group PL than in group P (medians of 5.7 to 6.1mg mL-1 in the P group versus 3.1 to 3.7mg mL-1 in the PL group). Measured lidocaine plasma concentrations (medians of 2.27 to 2.51mg mL-1) were in the range that result in analgesia and were below values that result in toxicity in dogs. The BIS values observed in the two groups of dogs were compatible with deep anesthesia (mean values of 43-46 and 45-49 in groups P and PL, respectively). Maintenance of deep anesthesia with lidocaine-propofol causes less cardiovascular depression than equipotent doses of propofol alone.

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Pós-graduação em Engenharia Mecânica - FEG

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Pós-graduação em Física - FEG

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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This review is intended to gather together recent studies that explore the effects of different types of noninvasive ventilation (NIV) on the autonomic nervous system, assessed through heart rate variability (HRV). A search for papers was conducted in the PubMed, PEDro, SciELO and Lilacs databases with the following descriptors: noninvasive ventilation, CPAP ventilation, intermittent positive pressure breathing and autonomic nervous system, for the period between 2008 and 2012. After eliminating papers not addressing the topic, we selected six studies, of which five applied NIV in CPAP mode and one used biphasic positive airway pressure. In general, the findings suggest that NIV promotes changes in autonomic modulation that are dependent on the conditions of the subjects analyzed and the time when these rates are assessed, meaning acute or long-term effects.