334 resultados para Associação assistencial
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O presente trabalho teve como objetivos relacionar o desempenho sexual das codornas japonesas com o canto, nos machos. Foi determinado o perfil de comportamento sexual das codornas e foi constatado que os machos apresentam diferenças individuais conspícuas entre os grupos de maus e bons copuladores. Foi descrito também a taxa de vocalização e determinados os parâmetros acústicos, entretanto mostraram-se semelhantes entre os grupos testados, apesar de apresentarem diferenças na estrutura sonográfica. Houve diferenças no índice gonadossomático entre os dois perfis, porém não se mostraram significativos. Não houve correlação entre o desempenho sexual de machos de codorna japonesa e a taxa de vocalização, apesar de uma tendência dos bons copuladores cantarem mais freqüentemente
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The Pirambóia Formation is a lithostratigraphic unit of the Paraná Basin, positioned between the Corumbataí (lower) and Botucatu (upper) Formations on the eastern edge of the basin. This unit is focused by many studies due to its great importance as an essential component in the Guarani Aquifer System (SAG) and the petroleum system “Irati-Pirambóia”, as excellent reservoirs. The Pirambóia Formation is historically the subject of several controversies on issues like age, contact relationships with the upper unit and depositional paleoenvironment. Despite these aspects, the Pirambóia Formation is commonly taken to be of Triassic age and is considered a product of wet aeolian systems, with plenty of wet interdunes and subordinate fluvial facies. In this work, by using techniques such as facies analysis, depositional architecture and facies association, facies of this unit were characterized and their depositional paleoenvironment was inferred particularly in Jundu Mining, region of Descalvado in northeastern São Paulo. Techniques such as grain size and petrographic analyses, aimed to characterize this unit as a potential reservoir rock. Five facies were described for the Pirambóia Formation in the studied region: St, Sh, Sm, Sr and Gt facies, generated by sedimentary processes of the bottom load type, mostly under low flow regime (with exception for the Sh facies, which is formed by upper flow regime processes). In addition to that, four facies associations were recognized from the architectural elements, primarily contained within the main channel: complex channel bars, composed by foreset macroforms (FM), sandy bedforms (SB) and gravel bars and bedforms (GB); flood deposits, constituted by laminated sand sheets (LS); deposits of hyperconcentrated flows and eolian deposits. It was interpreted that the Pirambóia Formation in Descalvado (SP) is the record of the sedimentation of braided rivers, with dunes and interdunes deposits...
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Introduction: Given the repercussion of the important role of physical activity in the prevention of sickness and non-communicable diseases / loss, many works have been done in order to understand the association of sociodemographic characteristics with sedentarism. The elements which influence the physical activity practice are countless. Besides the intrapersonal element, environment elements (social environment, cultural environment, public politics, information environment, natural environment etc.) are also important in the life style. Yet, the way that the person understands the environment can be considered in the planning of the strategies to change the sedentary behavior. Objective: Verify the association of the environment perception with the practice of physical activity (FA) at leisure time in adults living in Rio Claro – SP. Methodology: The sample consists of 470 adults, all residente in rio Claro-SP, aged ≥ 18 years old. The chosen participants answered to the questionnaires: Neighborhood Environmental Walkability Scale (NEWS), International Physical Activity (IPAQ) and to a specific questionnaire with personal data (age, sex, educational level, economical level, weight, height and marital status). The analysis of the connection between the variables was done through the Logistic Regression with Confidence Interval of 95%, using the software SPSS 17.0. Those who reached the recommendation of 10 minutes or more of physical activity in leisure time for week were classified as active, and those who did not reach the recommendation were classified as underactive. Results: The proportion of subjects who practiced physical activity in leisure time was 38,7%, and the male subjects, as well as those classified as better social level showed higher chances to practice at least 10 minutes weekly of physical activity during leisure. Still, walking the dog, soccer fields and gardens near the house (less than 10 walking minutes), were...
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As formigas da tribo Attini apresentam reconhecida simbiose com microrganismos: fungos mutualistas basidiomicetos nas famílias Lepiotaceae e Pterulaceae cultivados pelas formigas, bactérias actinomicetas ou no gênero Burkholderia produtoras de antibióticos contra fungos entomopatogênicos, fungos ascomicetos do gênero Escovopsis micófagos para o mutualista, e comensais como fungos, leveduras e bactérias que degradam celulose. Um novo mutualista é descrito no presente trabalho: uma espécie de bactéria no gênero Mesoplasma, detectada via PCR para 16S no DNA genômico de Attini derivadas (gêneros Acromyrmex, Atta, Serycomyrmex e Cyphomyrmex), intermediárias (Trachymyrmex) e basais (Apterostigma, Mycetarotes, Mycocepurus e Mycetagroicos). Uma única linhagem de Mesoplasma com baixíssima diversidade 16S esteve presente nas Attini, mas não em formigas de tribos filogeneticamente próximas a Attini, como Dolichoderini (Tapinoma sp), Camponotini (Camponotus sp), Cephalotini (Cephalotes sp), Crematogastrini (Crematogaster sp), Pheidolini (Pheidole sp) e Ponerini (Pachycondyla sp), indicando uma simbiose Mesoplasma-Attini recente e específica.
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Os mecanismos pelos quais o hiper e hipotireoidismo afetam o osso durante a menopausa são pouco conhecidos. O objetivo deste estudo foi verificar a ação do hormônio triiodotironina (T3), em diferentes concentrações associado ao estrógeno (E2) em concentração infra-fisiológica (condição de menopausa), sobre a proliferação de células de rato ROS 17/2.8, através de uma curva de crescimento para obtenção do tempo de dobramento (TD). As células ROS 17/2.8 são consideradas modelo de células osteoblásticas e foram cultivadas em meio HAM F-12, e submetidas ao tratamento hormonal com as combinações das concentrações fisiológica, infrafisiológica e suprafisiológica de T3 e infra-fisiológica de E2. Utilizamos como grupo controle aquele tratado com as concentrações fisiológicas dos dois hormônios. Para cada concentração hormonal foram realizadas 5 repetições, e as células contadas manualmente nos dias 1, 3, 5 e 7, após o início da adição hormonal. A análise estatística utilizada foi a técnica da análise de variância não paramétrica, complementada com teste de comparações múltiplas. Baseando-se nos resultados obtidos, pode-se concluir que o crescimento das células ROS 17/2.8 é afetado pelos tratamentos hormonais, em especial quando a concentração infrafisiológica de E2 está associada à concentração suprafisiológica de T3, aumentando o tempo de dobramento celular. Este efeito poderia tornar o metabolismo do osso mais lento, prejudicando a neoformação óssea em pacientes menopausadas e hipertireoidéas
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Preeclampsia (PE) is a pregnancy specific syndrome characterized by a systemic inflammatory response, with higher intensity than that observed in normal pregnancy. Cells of the immune system, such as monocytes and granulocytes are endogenously activated and secrete high levels of free radicals and inflammatory cytokines. The objective of this study was to assess the activation state of monocytes from pregnant women with preeclampsia by endogenous expression of TLR2 e TLR4 receptors and to correlate the expression of TLR2 and TLR4 on monocytes surface of pregnant women with PE with the production of tumor necrosis factor-alpha (TNF- and interleukin-10 (IL-10) by these cells stimulated or not with peptidoglycan (PG) and lipopolysaccharide (LPS), as agonists agents of TLR2 and TLR4, respectively. We evaluated 15 pregnant women with PE, 15 normotensive pregnant women (NT) and 15 non-pregnant (NP). Peripheral blood monocytes were incubates in the presence or absence of LPS or PG. The supernatant obtained after 18h of culture was aspirated and used for TNF- and IL-10 determination by enzyme immunoassay (ELISA). The endogenous expression of TLR2 and TLR4 receptors was evaluated by flow cytometry. Our results showed significant highly concentrations of TNF- and TLR4 expression in monocytes of preeclamptic women when compared with NT and NP. Normal pregnant women presented higher levels of IL-10 in comparison with PE and NP groups. TLR2 expression was similar in the three groups studied. Therefore, our study highlights the important role of TLR4 in PE and the consequent high production of TNF- by monocytes of these patients, as well as the potential mechanism involving low levels of IL-10 in the pathophysiology of the disease. These observations demonstrate the strong link between the pathology of PE and the immune system of these patients
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
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Plumbism is considered the oldest occupational disease. Among the pathophysiological effects associated with lead (Pb) are cardiovascular disorders. Many diseases that develop later in life are determined during the early stages of life, under the influence of exposure and preferred diet of the mother. Still, one should consider that many environmental contaminants at levels not harmful can determine pathophysiological processes if physical or chemical stressors and/or pathological conditions are present. In this context, the intrauterine malnutrition may represent an additional risk factor in exposure to Pb during pregnancy and lactation. For these reasons, the objective of this study was to evaluate the cardiovascular risk of weaned rats that have suffered perinatal exposure to Pb and intrauterine malnutrition, alone or in combination. After mating, female rats were divided into control (ctrl, ad libitum), food restriction (RA, the same diet 50% of consumption in the control group during pregnancy), exposed to Pb (500 ppm Pb in drinking water during pregnancy and lactation) and association (As, received the last two procedures in combination). Cumulative concentration-effect curves (CECs) to CaCl2 and noradrenaline (NA) were obtained in rings with and without endothelium of the same thoracic aorta from male weaned rats (23-25 days old). Maternal weight, litter weight, weight and number of pups at birth, anogenital distance, arterial blood pressure (ABP) and weight of tissues (kidney, liver, aorta, left ventricle) were evaluated. Changes in vascular reactivity were assessed by the maximum response (MR) and 50% effective concentration (EC50). Data were presented as mean ± SEM. Statistical analysis was performed by multifactorial analysis of variance and Tukey's post test. Body weight of dams did not differ between the experimental groups, except on the...(Complete abstract click electronic access below)
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This research was aimed at analyzing whether there is an association between the positioning of the pupil in the classroom and his academic performance, as well as to diagnose the main factors underlying the association. Thus, this study analyzed 4 Elementary School II institutions of both public and private educational systems, in Botucatu, São Paulo, Brazil during a school year bimester. To register the positions students were seated, 29 similar classes (containing 6 rows x 6 columns) were investigated, each one with around 30 students, which resulted in a sampling of 859 students. For the questionnaire application, which objective was to verify the main reason for students’ seat choice, the same 29 classes were investigated. However, the sampling number was reduced to 692 students. In turn, for the collection of school performance and absence percentage of each student for the bimester in question, teachers’ evaluation books were used. As a result, it was found that the lower the percentage of the student's absences, the greater is their performance at school, and the greater their performance at school is, the closer up front to the board they are seated. Finally, the closer up to the board they are seated, the more their motivation and interest in learning increase. Therefore, there is an association between the position of a student in the classroom and his or her academic performance, where the association is conditioned by the motivation and interest in learning
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A artrite reumatóide (AR) é uma doença inflamatória crônica de caráter autoimune que compromete as articulações. A maioria das terapias aprovadas para o tratamento desta e outras patologias autoimunes é baseada na inibição global da resposta imune, o que aumenta a susceptibilidade aos agentes infeciosos. O objetivo geral deste projeto foi definir se a associação de vitamina D (VitD3) com o antígeno proteoglicano (PG) é tolerogênica e serve como medida terapêutica. Para isso, utilizamos o modelo de artrite experimental obtido pela imunização de camundongos BALB/c com PG. Inicialmente, os animais foram imunizados com diferentes doses do antígeno específico (PG) na presença de VitD3 para determinação da dose tolerogênica. O potencial terapêutico da estratégia mais tolerogênica foi testado no período pré-clínico da doença, isto é, no período após o aparecimento do nível máximo de anticorpos anti-PG, mas antes das manifestações clínicas da artrite (eritema e edema articular). A eficácia terapêutica foi avaliada através da incidência de artrite e do escore clínico da doença. O possível mecanismo imunológico envolvido no efeito terapêutico foi estudado por avaliação dos níveis de citocinas (IL-6, TNF-α, IFN-γ, IL-10 e IL-17) produzidas por células esplênicas estimuladas in vitro com PG. Analisados em conjunto, os resultados obtidos mostraram que os três procedimentos (PG, VitD3 e PG+VitD3) determinaram efeito terapêutico. Entretanto, a análise mais detalhada, incluindo número de animais com escore clínico maior que oito (escore > 8), início dos sintomas clínicos e escore máximo atingido, sugere que o uso de PG50 (50μg de PG) associado à VitD3 ou o uso isolado de VitD3 foram os procedimentos terapêuticos mais eficazes. A produção mais elevada de IL-10 nestes dois grupos sugere contribuição desta citocina neste efeito terapêutico
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Pós-graduação em Biociências - FCLAS
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Pós-graduação em Agronomia (Ciência do Solo) - FCAV
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Pós-graduação em Medicina Veterinária - FCAV