Memorial do fim: as várias faces de Machado de Assis

Este artículo se centra en el análisis de la novela Memorial do fim: a morte de Machado de Assis (1991), de Haroldo Maranhão. Basándose en las formulaciones teóricas de Linda Hutcheon en su Poética del postmodernismo (1991), analizamos la reelaboración paródica de la biografía de Machado de Assis presente en la novela. Esta práctica paródica, que se caracteriza por su dualidad contradictoria de la continuidad y la transgresión, es la principal característica de la narrativa posmoderna en esta novela de Haroldo Maranhão.

Validação de técnica hemostática do complexo arteriovenoso ovariano na ovariosalpingohisterectomia de gatas

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Todo o conhecimento do munda na literatura: as disciplinas do currículo nacional dos anos iniciais do ensino fundamental em Cacoete, de Eva Furnari. -

Nous comprenons que la littérature, quelle que soit l'adjectif qui accompagne - enfant, adolescent ou adulte - est l'art. L'art de la parole qui crée des mondes possibles, pas réel, à travers un langage très élaboré et complexe qui permet la compréhension de toute la l'expérience humaine. D'autre part, la réalité de l'éducation brésilienne nous montre que nos étudiants ont de la difficulté à comprendre des textes écrits, ce que compromettre l'apprentissage de toutes les matières du programme. Dans ce sens, cette étude a eu l'óbjective à à souligner les possibilités que nous avons d'incorporer la literature brésilienne pour les enfants e les jeunes - appropriée aux étudiants de l'enseignement de base, les enfants et les jeunes - comme um élément transdisciplinaire, associant toutes les disciplines du programme scolaire de l'école élémentaire, notre découpure. Ainsi, nous le signalons dans Cacoete, d' Eva Furnari (2005), des éléments de toutes les matières du programme d'études de cette étape scolaire Brésilienne, afin de montrer aux les enseignants de tous les domaines qui le travail avec la littérature conduit nécessairement à la compréhension de toutes la connaissance. Notre étude a été réalisée sous une approche qualitative de caractère bibliographique. Pour l'embasement théorique nous utilisons de auteurs qui recherche le concept et les spécificités du texte littéraire, selon Rolland Barthes (2007) et Tzvetan Todorov (2009) aussi que des auteurs qui l'étudient spécifiquement de la littérature pour les enfants, selon Nelly Novaes Coelho (2006) et Fanny Abramovich (1983; 1999). Ils ont été également consultées des auteurs qui recherche sur la lecture, la littérature et l'école, selon John Wanderley Geraldi (2006), Marisa Lajolo (1997), Ana Maria Machado (2011), Iara Conceição Bitencourt Neves et al (2003), Roxane Rojo (2002), Ezequiel Theodoro da Silva (1988)...

A new heterologous fibrin sealant as scaffold to recombinant human bone morphogenetic protein-2 (rhBMP-2) and natural latex proteins for the repair of tibial bone defects

Tissue engineering has special interest in bone tissue aiming at future medical applications Studies have focused on recombinant human bone morphogenetic protein-2 (rhBMP-2) and natural latex proteins due to the osteogenic properties of rhBMP-2 and the angiogenic characteristic of fraction 1 protein (P-1) extracted from the rubber tree Hevea brasiliensis. Furthermore, heterologous fibrin sealant (FS) has been shown as a promising alternative in regenerative therapies. The aim of this study was to evaluate these substances for the repair of bone defects in rats. A bone defect measuring 3 mm in diameter was created in the proximal metaphysis of the left tibia of 60 rats and was implanted with rhBMP-2 or P-1 in combination with a new heterologous FS derived from snake venom. The animals were divided into six groups: control (unfilled bone defect), rhBMP-2 (defect filled with 5 mu g rhBMP-2), P-1 (defect filled with 5 mu g P-1), FS (defect filled with 8 mu g FS), FS/rhBMP-2 (defect filled with 8 mu g FS and 5 mu g rhBMP-2), FS/P-1 (defect filled with 8 mu g FS and 5 mu g P-1). The animals were sacrificed 2 and 6 weeks after surgery. The newly formed bone projected from the margins of the original bone and exhibited trabecular morphology and a disorganized arrangement of osteocyte lacunae. Immunohistochemical analysis showed intense expression of osteocalcin in all groups. Histometric analysis revealed a significant difference in all groups after 2 weeks (p < 0.05), except for the rhBMP-2 and FS/rhBMP-2 groups (p > 0.05). A statistically significant difference (p < 0.05) was observed in all groups after 6 weeks in relation to the volume of newly formed bone in the surgical area. In conclusion, the new heterologous fibrin sealant was found to be biocompatible and the combination with rhBMP-2 showed the highest osteogenic and osteoconductive capacity for bone healing. These findings suggest a promising application of this combination in the regeneration surgery.

Characterization of calcium phosphate coating produced by biomimetic method

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Molecular detection of hemotrophic mycoplasmas among domiciled and free-roaming cats in Campo Grande, state of Mato Grosso do Sul, Brazil

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Ehrlichia canis (Jaboticabal strain) induces the expression of TNF-alpha in leukocytes and splenocytes of experimentally infected dogs

Canine ehrlichiosis is caused by the bacterium Ehrlichia canis and is characterized by a systemic febrile disease of unknown pathogenesis. This study evaluated the expression of cytokines TNF-alpha, IL-10, IFN-gamma, in splenic cells and blood leukocytes during the acute phase of ehrlichiosis and after treatment with doxycycline hyclate in dogs experimentally infected with the E. canis Jaboticabal strain. The study results showed a significant expression of TNF-alpha 18 days post-inoculation, reducing by approximately 70% after treatment. There was a unique peak of expression of IL-10 and IFN-gamma 18 and 30 days post-inoculation, respectively. This study suggests that TNF-alpha plays a role in the pathogenesis of the acute phase of canine ehrlichiosis and that treatment with doxycycline hyclate reduces the systemic effects of this cytokine, possibly by reducing or eliminating parasitemia.

Sports practice is related to parasympathetic activity in adolescents

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Osteoblast differentiation is enhanced by a nano-to-micro hybrid titanium surface created by Yb:YAG laser irradiation

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Planejamento Ambiental da Bacia Hidrográfica do Córrego Guaiçarinha, Município de Álvares Machado, São Paulo, Brasil

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Uma ponte entre o Brasil e a França: histórias da meia-noite, de Machado de Assis

Pós-graduação em Letras - FCLAS

Portugal finissecular nas crônicas de D. João da Câmara publicadas na revista portuguesa O Ocidente e no jornal brasileiro Gazeta de Notícias (1901-1905)

Pós-graduação em Letras - FCLAS

Rastros em chão branco: o sertão de João Guimarães Rosa entre percepções e memórias de travessias

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Transmissão congênita em cabras reinfectadas com Toxoplasma gondii

This study evaluated the potential of congenital transmission in goats experimentally infected and reinfected with Toxoplasma gondii, in three gestational stages (initial, intermediate and final). Of the 25 non-pregnant females negative for T. gondii, 20 were orally inoculated with 2.5 x 103 T. gondii ME49 oocysts. Of these, 15 pregnant females chronically infected were reinoculated, via oral, with 2.5 x 103 T. gondii VEG oocysts. Five experimental groups were formed (n=5): I, II and III (reinoculations in the initial, intermediate and final gestational stage, respectively), IV (inoculation) and V (no inoculation). Clinical and serological exams (IgG IFAT [indirect immunofluorescence antibody test]) in different days of evaluation, and bioassay and PCR were performed in all goats. In the infected goats with T. gondii a peak of 40.2°C (IV) at nine, seroconversion (IgG≥64) at 21 and stabilization (IgG<1024) at 119 days postinoculation were observed. In the reinfected goats with T. gondii occurred an increase in IgG titers (≥1,024) at 28 (I), 7 (II) and 3 (III) days post-reinoculation. During kidding were observed only in the reinfected groups: dystocia, malformation body, stillbirth and weakness, and IgG anti-Toxoplasma were detected in all and in some offsprings of the reinfected and infected goats, respectively. Tissue parasitism by T. gondii was diagnosed by bioassay and PCR in infected and reinfected goats and in their offspring. The congenital toxoplasmosis was possible in goats chronically infected and reinfected with T. gondii. The primary infection with T. gondii did not protect the pregnant goats against congenital disease resulting from toxoplasmic reinfection, in different gestational stages (initial, intermediate and final).

A recepção de Machado de Assis por jovens leitores do século XXI

Pós-graduação em Letras - FCLAS