Efeitos da ciclosporina a sobre a função renal de cães da raça Golden Retriever normais ou afetados pela distrofia muscular

The muscular dystrophy of Golden Retriever is a degenerative miopaty caused by the absence of dystrophy and it is genetically homologue of the Duchenne muscular dystrophy in humans, so, these dogs are considerably experimental models for studies on cellular therapy. Their successful depends of the adequate immunosuppression. Cyclosporin A is indicated for that and the monitoring of blood concentration and adverse effects are essential to viabilise the therapy. It was studied GRMD dogs, and normal dogs from the same breed, submitted for therapy with CsA, associated, on GRMD, of cell transplantation. It was evaluated the possible effects of the drug on renal functions. It has been considerate the clinic manifestations, urinalisis, testis of glomerular function and blood concentrations of urea, cretinine, sodium and potassium. In our results we found a discrete increase of blood urea on booth groups; increased levels of urine's cylinders and protein and also increase of urinary density on GRMD group. CsA therapy could make acute lesions on renal tubules, especially on GRMD. These dogs also have different reactions than normal dogs on relation of ions homeostasis and renal function. However, earlier diagnosis and adequate treatment could prevent the development of renal diseases.

Cobertura da cultura da soja pela calda fungicida em função, de pontas de pulverização e volumes de aplicação

The goal of this research was to evaluate two tips of spraying nozzles (hollow cone nozzle and two flat fan nozzle annexed to a nozzle body DUO) and three spray volumes (100, 150 and 200 dm3 ha-1), whose application was for the control of the Asian soybean rust. An area of 288 m 2 was used, with a randomized blocks design in a factorial 2×3 with 4 repetitions, total of 24 experimental parcels of 12 m2. For the spraying with hydraulical nozzles a costal spray of constant pressure kept by C02 compressed with bar of 2 m was used. The analysis of the covering percentage was carried through by means of the use of hidro-sensible paper, that was placed in three position of the plant what it represents, in height, the third superior, average and inferior of the canopy. For both the third no interaction between the evaluated factors, was found and meither difference statistics between the spraying tips and the volumes. In absolute values the twin flat fan nozzle DUO presented minimum difference of covering in relation to the hollow cone nozzle, and for the spray volume of 200 dm3 ha -1 presented greater covering percentage.

Produção de agaricus blazei ss. Heinemann (A. brasiliensis) em função de diferentes camadas de cobertura e substratos de cultivo

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Crescimento de cultivares de mamoneira em função da aplicação de boro, durante a formação de mudas

It was objectified to quantify the initial growth of varieties of castor bean with boron fertilization. Had been tested to cultivate they AL-Guarani, Mirante 10 and Nordestina to the doses of 0; 0.25; 0.50; 0.75 and 1.0 mg kg -1 of B in controlled environment of greenhouse in the Sector of Cafeicultura of the Department of Agriculture of the UFLA. The characteristics valued were: height of plants, length of roots, leaf number, diameter of stem, mass of dry substance (MS) of leafs, of stem, the root and total. To cultivate Mirante 10 it was the one that got minor growth of the system of root. For leaf number to cultivate AL-Guarani it was superior to Mirante 10 and Nordestina. Also to cultivate better AL-Guarani if it detached how much to the production of total mass of MS, while to cultivate Mirante 10 produced more mass of MS than Nordestina.

Desenvolvimento e nutrição do capim-Tanzânia em função da aplicação de zinco

It was aimed to assess the effects of zinc in the development and nutrition of Tanzania grass. The experimental design used was fully randomized, consisting of six doses of zinc (0, 15, 30, 60, 120 and 240 mg dm'3) and four repetitions. The experimental unit was formed in a vase filled with a Red Latosol dystrophic (Zn = 0.4 mg dm). There were two cuts, the first after 53 days of transplanting seedlings and the second 35 days after the first cut. Was evaluated the concentration of zinc in the soil, the content of zinc leaf, the number of tillers, number of leaves, plant height, the dry mass of the shoot, root system and the whole plant. The doses of zinc influenced the concentration of zinc in soil and plant, and production of dry mass of Tanzania grass, especially the first cut. The Tanzania grass shows high tolerance to the toxicity of zinc, and toxic critical level of 273 mg kg-1.

Custos e rentabilidade do milho em função do manejo do solo e da adubação nitrogenada

Agronomic practices that help farmers to raise yield and reduce costs must be studied to ensure agricultural sustainability. Thus, the objective of this study was to analyze economically the effect of soil management and nitrogen fertilization in maize crops. Treatments consisted of a combination of 3 soil management techniques (plow harrows + floating harrows, chisel + floating harrows, and no-tillage), 5 periods of nitrogen fertilization (control - 0 kg ha -1 N; 120 kg ha -1 after sowing (S); 120 kg ha -1 in the V 6 stage; 30 kg ha -1 (S) + 90 kg ha -1 in V 6; 30 kg ha -1 (S) + 45 kg ha -1 in V 4 + 45 kg ha -1 in V 8 The total operating cost (TOC), gross revenue (GR), operating profit (OP), profitability index (PI), break-even yield, and break-even price were estimated. It was concluded that the no-tillage system, after 11 years of management, associated with nitrogen fertilization promotes positive PI and OP, being useful to farmers.

Proteína e qualidade de sementes de feijão (Phaseolus vulgaris L.) em função da adubação nitrogenada em plantio direto

Nitrogen limitation in the common bean (Phaseolus vulgaris L.) produces reduced productivity and seeds with low protein content and physiological quality. We assessed the effects of nitrogen fertilizer side dressing on the protein content and physiological quality of the seeds of P. vulgaris L. cultivars (cv.) IPR Juriti and Pérola grown in plots (soil type = Dystrophic Red Latosol) using a no-tillage system under a thick mulch of millet residues at the Experimental Station of UNESP-Ilha Solteira campus, located in Selvíria, MS (Köppen climate type = Aw) during autumn (March/June) and winter (June/September) 2005. For each cultivar, a randomized block experimental design was used with four replicates and factorially arranged treatments equivalent to 0, 30, 60, 90 and 120 kg.ha-1 added nitrogen (as urea, containing 45% of N) applied as a side dressing during the V4-3 and V4-6 phenological stage corresponding to the 3rd and 6th completely opened trifoliolate leaf on the main stem. Supplementation with up to 120 kg.ha-1 nitrogen promoted a greater increase in crude protein at V4-3 (unsupplemented = 17.6% and 16.3%; 120 kg.ha-1 N = 24.1% and 22.3% for cv. IPR Juriti and Pérola, respectively) than at V4-6 (unsupplemented = 19.2% and 18.3%; 120 kg.ha-1 N = 21.3% and 20.3% for cv. IPR Juriti and Pérola, respectively). About 90% of the crude protein from cv. IPR Juriti was composed of soluble protein compared to 72% for the cv. Pérola. Albumins and globulins represented about 80% of the soluble protein and prolamins were lower at 0.6%. In conclusion, nitrogen fertilization up to 120 kg.ha-1 applied as a side dressing at the V4-3 phenological stage in no-tillage under a thick mulch of millet promoted a greater increase of crude protein in common bean seeds than at the V4-6 stage. The highest accumulation of soluble protein occurred at 90 kg.ha-1 applied nitrogen without having a significant influence on the physiological quality of the seeds.

Desempenho de semeadora-adubadora em função do prepa ro de solo e espa çamento da cultura do milho

The performance of machines and agricultural implements are of fundamental importance, especially when subjected to different types of soil tillage, and have to adapt to these conditions, in order to promote good operational performance. The objective of this study was to analyze the operational performance of a Marchesan Supreme Cop grain drill, equipped with four rows, spaced 0.90 m, according to three types of tillage: conventional tillage (plowing and two harrowing series), reduced tillage (scarification with a roller), and no-tillage, in areas previously seeded with maize (Zea mays L.), at two spacing measures (0.90 m and 0.45 m). The results indicate that the demand for power, tensile stress, and motor rotation, in the sowing operation, were not influenced by tillage and maize crop. The tractor wheel slip showed different results, being lower in no-tillage and higher in conventional and reduced tillage.

Conhecimento Odontológico e Comportamento de Retorno de Escolares em Função do Tipo de Instituição (Pública ou Privada)

Objective: To evaluate the dental knowledge and attendance of elementary schoolchildren according to the type of institution (public or private). Method: The sample was composed of 800 children from the 5th to 8th grades of the elementary education. The research instrument was a questionnaire composed of open questions referring to the last recall visit, type and importance of the recall visit, and knowledge of dental caries and periodontal disease. Descriptive statistical analysis was done and the chisquared test was used with a significance level of 5%. Results: There was statistically significant difference between the students from the different institutions regarding the time (p=0.001) and main reason (p=0.001) of the last visit to the dentist, knowledge of the need of periodic visits to the dentist (p=0.001), importance (p=0.001) and frequency (p=0.001) of periodic recalls, and knowledge of dental caries (p=0.001) and periodontal disease (p=0.001). Conclusion: The adolescents presented different dental knowledge and attendance, according to the type of teaching institution.

Propriedade físico-química da própolis em função da sazonalidade e método de produção

The aim of this work was to investigate monthly, for one year the seasonality effect on the physicochemical properties (dry weight, flavonoids contents, pH and antioxidant activity) of ethanolic extract (EAP) of propolis produced by three different techniques (intelligent propolis collector, plastic screen or scraping) fifteen colonies of africanized bees. No differences (p>0.05) in the physicochemical properties due to the technique of propolis production and seasonality were observed.

Avaliação da função glomerular de cães sadios e nefropatas sob estimulação dopaminérgica

Dopamine is an endogenous compound widely used in intensive care. It has a broad spectrum of action, on the cardiovascular system and urinary tract. Increased glomerular filtration rate, renal blood flow and fractional excretion of sodium and phosphorus are expected renal effects in normal individuals, but are poorly explored in veterinary medicine. This study was conducted to evaluate the glomerular function of dogs with renal disease submitted to continuous infusion of dopamine. Different doses of dopamine were administered in healthy and nephropathic dogs. Laboratory evaluations of creatinine clearance and urinary protein/creatinine ratio were performed during and after treatments. Creatinine clearance showed dose-dependent increase in healthy dogs. In dogs with renal disease, the dose of 1μg/kg/min GFR increased slightly, without changing the urine P/C and blood pressure, while the dose of 3μg/kg/min increased urinary protein excretion.

Emergência de plantas daninhas em função da posição da semente e quantidade de palha de cana-de- açúcar

This work was carried out to evaluate the effects of sugarcane straw density and positions of seeds of Euphorbia heterophylla, Mucuna cinereum, Digitaria nuda and Eleusine indica on emergence and initial development of plants. The experiment were arranged in a completely randomized design, with 15 treatments and four replications, in a factorial arrangement 3 x 5 with a additional control; the first factor was constituted by position of seeds related to the straw (under, between and on) and the second by five quantities of straw (1, 2, 4, 8 e 16 t ha -1) with a control without straw. At 15 days after sowing (DAS) it was realized evaluations of height, dry mass and emergence percentage for E. heterophylla and M. cinereum, and at 28 DAS it was analyzed dry mass and emergence percentage for D nuda e E. indica. Data obtained were submitted to F in variance analysis test and means were compared with Tukey at 5% probability. Emergence and initial development of E. heterophylla e M. cinereum were reduced with increasing of straw and were affected by seed position, but it was not inhibited in none of conditions, indicating aggressiveness of these weeds in sugarcane mechanized harvest conditions. D. nuda and E. indica emergence was not affected by seed position and coverage soil with 8 e 16 t ha -1 of sugarcane straw inhibited its emergence.

Produção de rúcula e acúmulo de nitrato em função da adubação nitrogenada

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Avaliação da uniformidade de aplicação de água em gotejadores em função do teor de ferro

Este trabalho teve por objetivo estudar a variação de vazão em tubogotejadores NaanPC laranja e NaanPC azul em função de precipitados químicos, ao longo do tempo de funcionamento, quando submetidos a uma água rica em ferro, avaliando-se especificamente o coeficiente de uniformidade de Christiansen (CUC) e o coeficiente de uniformidade de distribuição (CUD). O experimento foi desenvolvido em uma bancada de ensaios para tubogotejadores no Laboratório de Ensaio de Equipamentos para Irrigação do Departamento de Engenharia Rural da Faculdade de Ciências Agronômicas - UNESP, localizado no município de Botucatu – SP. O experimento foi montado em esquema fatorial 2x2x7, sendo duas doses de Fe, dois modelos de gotejadores e sete tempos de funcionamento, com três repetições, totalizando 84 parcelas experimentais. Efetuou-se a análise de variância pelo teste F. As médias das vazões dos gotejadores foram comparadas pelo teste de T de Student a 5% de probabilidade. Os resultados obtidos não apontaram diferença significativa nas diferentes doses de ferro. Entretanto, os resultados apontaram diferença significativa na interação gotejador x tempo e coeficiente de uniformidade de Christiansen (CUC).

Crescimento inicial do eucalipto em função da aclimatação em viveiro

This study aimed to evaluate the acclimatization effects in the Eucalyptus grandis vs. Eucalyptus urophylla seedlings nursery in their initial growth in two soils types, clay and sandy. The seedlings were planted in Plantmax substrate and in rice hulls plus vermiculite, and managed, after 60 days of the mass propagation (DAE), during the rustication. There were five different frequencies of subsurface drip irrigation, restoring the soil field capacity condition: F1, F2, F3 and F4, which were irrigated once, twice, three and four times a day, respectively, and FD, kept in continue irrigation until planting at 90 DAE. In a randomized block design with four replications, plant height (HPA) were evaluated at 6 and 13 months after planting and the diameter at breast height (DAP) at 13 months after planting. Findings show that water management at hardening phase seedlings had no influence on growth in both soils.