Proteinograma sérico, com ênfase em proteínas de fase aguda, de bovinos sadios e bovinos portadores de enfermidade aguda de ocorrência natural

Nas últimas décadas, as proteínas de fase aguda (PFAs) tornaram-se biomarcadores de escolha em medicina humana para identificação e monitoração de doenças. Não há razão para imaginar que tais pesquisas clínicas não sejam igualmente úteis na medicina veterinária. Com o objetivo de verificar a importância das PFAs como biomarcadores de doenças inflamatórias em bovinos, determinou-se o proteinograma sérico, por meio da técnica de eletroforese SDS-PAGE, com interesse especial nas PFAs. Foram utilizados 30 animais, distribuídos em dois grupos: 15 bovinos sadios e 15 bovinos doentes (cinco com mastite estafilocócica, cinco com fotossensibilização e cinco com onfaloflebite). Os animais foram submetidos a colheitas diárias de sangue durante sete dias, enquanto internados no Hospital Veterinário da Unesp, Campus de Jaboticabal. Ceruloplasmina e haptoglobina apresentaram elevação significativa em animais acometidos por mastite, fotossensibilização e onfaloflebite (275,17% e 343,71%; 175,17% e 230,19%; 114,47% e 144,47%, respectivamente). A α1-glicoproteína ácida foi um bom biomarcador apenas em animais com mastite e fotossensibilização, elevando, respectivamente, suas concentrações séricas em 198,14% e 145,89%. Fibrinogênio mostrou-se um indicador confiável apenas em bovinos com mastite, com elevação de 146,5% em relação ao grupo sadio. Ficou clara a diferença na responsividade de distintas PFAs frente a diferentes estímulos inflamatórios. Ceruloplasmina e haptoglobina foram biomarcadores mais sensíveis e, portanto, mais confiáveis entre as PFAs estudadas nessa espécie.

Proteinograma sérico e do líquido peritoneal de equinos hígidos e daqueles submetidos à obstrução intestinal experimental

Avaliou-se a resposta de fase aguda através da concentração das proteínas de fase aguda (PFA) no soro sanguíneo e no líquido peritoneal de vinte e um equinos, hígidos e submetidos à obstrução intestinal experimental, distribuídos em quatro grupos: obstrução de duodeno - GD (n=6), íleo - GI (n=6), cólon dorsal esquerdo - GM (n=6) e controle instrumentado - GC (n=3). Foram colhidas amostras de sangue e líquido peritoneal e, após centrifugação e fracionamento, as proteínas de fase aguda foram separadas por eletroforese em SDS-PAGE. Identificaram-se as proteínas IgA, ceruloplasmina, transferrina, albumina, IgG, haptoglobina, α1-glicoproteína ácida e P24, no soro e no líquido peritoneal. Houve aumento nas concentrações sérica e peritoneal de todas as PFA, sendo mais evidente no líquido peritoneal e nos animais obstruídos. O fracionamento eletroforético das PFA no líquido peritoneal é mais eficaz no diagnóstico de processos inflamatórios abdominais, quando comparado ao sérico.

Spatial memory in sedentary and trained diabetic rats: Molecular mechanisms

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Study of Thermodegradation and Thermostabilization of Poly( lactide acid) Using Subsequent Extrusion Cycles

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Mechanical and Thermal Properties of Thermoplastic Random Copolyesters Made from Lipid- Derived Medium and Long Chain Poly (x-hydroxyfatty acid) s

The physical properties of novel thermoplastic random copolyesters [-(CH2)(n)-COO-/-(CH2)(n)-COO-](x) made of long (n=12) and medium (n=8) chain length -hydroxyfatty esters [HO-(CH2)(n)-COOCH3] derived from bio-based vegetable oil feedstock are described. Poly(-hydroxy tridecanoate/-hydroxy nonanoate) P(-Me13-/-Me9-) random copolyesters (M-n=11,000-18,500 g/mol) with varying molar ratios were examined by TGA, DSC, DMA and tensile analysis, and WAXD. For the whole range of P(-Me13-/-Me9-) compositions, the WAXD data indicated an orthorhombic polyethylene-like crystal packing. Their melting characteristics, determined by DSC, varied with composition suggesting an isomorphic cocrystallization behavior. TGA of the P(-Me13-/-Me9-)s indicated improved thermal stability determined by their molar compositions. The glass transition temperature, investigated by DMA, was also found to vary with composition. The crystallinities of P(-Me13-/-Me9-)s however, were unaffected by the composition. The stiffness (Young's modulus) of these materials was found to be related to their degrees of crystallinity. (c) 2014 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014, 131, 40492.

Establishment of peritoneal liquid electrophoretogram from healthy horses and horses submitted to experimentally induced intestinal obstruction

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Contribuição das redes de T.I. para formulação da estratégia e gestão das empresas

Pós-graduação em Engenharia de Produção - FEB

An innovative material based on natural rubber and leather tannery waste to be applied as antistatic flooring

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Electrochemical Properties of the Oxo-Manganese-Phenanthroline Complex Immobilized on Ion-Exchange Polymeric Film and Its Application as Biomimetic Sensor for Sulfite Ions

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Interface com o AEDROMO (Ambiente experimental e didático com robôs móveis) utilizando sistema Android

The AEDROMO (Experimental and Didactic Environment with Mobile Robots) is a versatile, user friendly and scalable environment that supports a wide range of experiments. In it there is an area that is similar to a desk where objects can interact with each other, including robots and other objects, and thus can perform numerous activities. In it's current state, AEDROMO has client computers that interact with the system through an interface, and thus realize the communication between the user and AEDROMO. This project offer support to create a new form of interface for AEDROMO and can therefore be used for devices running Android, the app developed in this project will serve as a basis for future work on this new interface

Caracterização gfeológico-geotécnica aplicada a gestão de risco no gasoduto GASBOL, trecho Ipeúna/SP - Itirapina/SP

The pipelines are characterized by the great length and linearity, these enterprises are usually associated with the horizon of soil and decomposed rock and accidents in this system usually have high complexity. So this work proposes a study of geological and geotechnical characterization of approximately 40 km ² and a study of risk analysis along 18.3 km of gas pipeline GASBOL, in the municipalities of Ipeúna-SP and Itirapina-SP, in scale 1:25.000, besides correlation between studies. The method for geological and geotechnical characterization is based on physiographic integrated analysis technique, which is supported by literature research, observation and interpretation of satellite imagery (photointerpretation), correlation of products numerical model of ground, fieldwork. The method adopted for risk classification is based on preliminary analysis of hazards (APP) technique, which is identified the geological process, this feature is classified as the susceptibility of occurrence, and then classified as the possible consequence of the process, if this evolves. As a product of the research, we designed a map in 1:25,000 scale, containing a table of geological and geotechnical characteristics of the mapped drives, as well as sectorization risk in each section of the pipeline. Were mapped geological and geotechnical seven units in the study area, delimited in excerpts of which five are classified as high risk, totaling 1.1 km in length of 18.3 km total

Análise da expansão urbana da cidade de Piracicaba no período de 2006-2011

The fundamental objective of this research was analyzed the urban expansion’s process of municipality Piracicaba, it is located in the countryside of São Paulo state. The use and occupation of land by observing the social and environmental impacts related, including the Protection Permanent Area (PPA) of urban fringes according to the successive expansions of Piracicaba city in 2006, the publication year of the current city hall director planning, until 2011, when the approval of the eighth and most recent update of Piracicaba’s expanding the perimeter. The development of the study was conducted with the support of bibliographic, cartographic, considering maps and satellite images, further more field work. Thematic maps of the current urban expansion were created, urban voids and land use were developed, typifying the occupation according to the activities established thus through the analysis of land use through cartographic interpretation, as research in locus. To assist the research geotechnologies were used, both for production and for the interpretation of cartographic materials, specially in Geographic Information Systems

Geoprocessamento na análise da vulnerabilidade ambiental desencadeada pela monocultura de cana-de-açúcar na bacia do distrito Santa Olímpia (Piracicaba/SP)

Sugar cane production is of the utmost importance to the economy of the entire Brazil, due to its multiple utility, being used as the raw material for the manufacture of various items, particularly, sugar and alcohol. In areas of sugarcane monoculture, the appropriate management of soils and water is essential, not only for the maintenance of the quality of the environment, but also for the quality of life of the population. Among the main impacts generated by the cultivation of sugar cane, stands out the withdrawal of the riparian forest, which is essential to the balance and maintenance of the ecosystem. Before that, the present work aimed at mapping the environmentally vulnerable areas in the basin of a tributary of the Corumbataí river, located in the district Santa Olímpia, in the city of Piracicaba-SP. For the purpose, techniques were used in Geoprocessing, aiming to produce thematic maps of Slope, for the Use and Occupation of Land, of Permanent Preservation Areas (APP), Soil and Geological of the basin of interest. From these mappings, the analysis was performed multi-criteria, which resulted in the Map of Environmental Vulnerability. This mapping environmental assessment of the study area, indicating proposals of practices for the management and conservation of soil and water resources, for the purpose of improving the environmental quality of the analyzed area. In this way, the research of this nature, may help in the decision-making on the part of the governmental bodies as well as civil society

Mapeamento do uso da terra como subsídio a um plano de recuperação das áreas de preservação permanente no entorno da represa de Salto Grande - Americana - SP

Currently, the dam of Salto Grande is very degraded. Water quality is seriously amended, and lack of riparian vegetation, as well as the advance of feed crops and land occupation in areas that should be permanently preserved, only complicate this situation. The permanent preservation area is essential for the water sources protection, soil erosion control and consequent watercourse sedimentation. Through aerial photography, using GIS techniques, it was able to identify the outwards bounds of the dam, to demarcate the permanent preservation areas and generate maps for land use. With this data, in addition to studies and ideas of reforestation in different environments, the development of a plan for restoration of degraded areas surrounding the dam is easier to be done. This study confirmed that about 72% of land use in permanent preservation areas is not in accordance with specific laws, making necessary its recovering.

Simulação de produção de sedimentos em microbacias em função de cenários de restauração florestal

In São Paulo state, deforestation and agriculture activities are increasing soil losses processes, especially in areas of susceptible soils where properties not adopt soil conservation practices. Environmental adequacy at property level regarding Permanent Protection Areas and Legal Reserves is considered a factor on reducing soil losses and considering that we assessed soil losses of different scenario of environmental adequacy. Simulations of erosive process were carried out in 15 catchments of Corumbataí river basin, according to different forest restoration scenarios, as well as the current situation of land use/land cover. The scenarios include the implementation of Permanent Preservation Areas (PPA), the reforestation of variable source areas, and two scenarios, the Legal Reserve installation in 20% of each catchment, being one of them for most critical areas in terms of erosion and the other at random. It was observed that the establishment of PPA and the reforestation of hydrologically sensitive areas, offered only a small contribution to the control of the erosive process, resulting in a reduction of 10% and 7,8%, respectively, while the legal reserve in critical areas has a significant reduction of 69,8%. The random scenario, in turn, resulted in a reduction of only 21,4%. Results show that reforestation could reduce soil losses, but previous studies of land prioritization and planning could increase significantly its efficiency at this process.