276 resultados para 1-min average


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Pós-graduação em Engenharia Civil e Ambiental - FEB

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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O núcleo parabraquial lateral (NPBL) e o núcleo Kölliker-Fuse (KF) são os mais importantes núcleos da ponte envolvidos com o controle da ventilação pulmonar (VE) e são conhecidos como grupo respiratório pontino ou centro pneumotáxico. Vários experimentos demonstraram que a estimulação ou a lesão do NPBL-KF produziram alterações nos padrões respiratórios. No entanto, ainda não estava claro qual seria a área exata (no complexo NPBL-KF) e o neurotransmissor envolvido nas alterações respiratórias. Estudos com imunohistoquímica demonstraram a presença de receptores purinérgicos (especialmente os P2X) em várias áreas envolvidas com o controle da ventilação, incluindo o NPBL. Estudos também demonstraram a presença de um denso plexo de varicosidades imunorreativas para o GABA ao longo do complexo NPB-KF, sendo que o processamento neural nessa região estaria sob forte inibição gabaérgica. No entanto, o papel dos receptores purinérgicos e gabaérgicos do NPBL na regulação da VE em ratos não anestesiados ainda não tinha sido investigado. Desta forma, no presente estudo investigamos as respostas ventilatórias após a injeção do α,β-metil-ATP (agonista purinérgico), do PPADS (antagonista purinérgico) e do muscimol (agonista GABA-A) no NPBL de ratos não anestesiados. Foram utilizados ratos com cânulas de aço inoxidável bilateralmente no NPBL, os animais foram submetidos a pletismografia de corpo inteiro para que fossem obtidas as medidas de VE. As injeções bilaterais do agonista purinérgico, α,β-metil-ATP (2 nmol/0,2 μl, n=8), no NPBL promoveu queda na freqüência respiratória (fR) (108  5 ciclos/min vs basal 137  6 ciclos/min, p = 0,005), não alterou o volume corrente (VT) (2  0,3 ml/kg vs basal 2  0,3 ml/kg, p = 0,967) e queda na VE (263  42 ml.kg-1.min-1 vs basal 325  43 ml.kg-1.min-1, p = 0,001)... (Resumo completo, clicar acesso eletrônico abaixo)

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Pós-graduação em Odontologia Restauradora - ICT

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National Council for Scientific and Technological Development (CNPq)

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The aim of this study was to evaluate the presence of residues of sodium hypo-chlorite gel, chlorhexidine gel, and EDTA gel on dentina l walls after canal preparat ion throughchemical SEM- elemental chemical microanal ys is (EDS) analysis. Forty-eight single-rootedteeth were selected. They had their crowns sectioned and were instrumented with a reciprocat-ing system. The canals were irrigated with 5 mL of saline solution during root canal preparation.After instrumentation, the root canals were irrigated with 3 mL 17% EDTA followed by 1 min ofultrasonic passive activation (33 20 sec) to remove the smear layer, and then irrigated with3 mL of saline solution. The specimens were randomized into three groups (n 5 12) accord ing tothe chemical substance that filled the root canal for 30 min: GI: 5.5% sodium hypochlorite gel;GII: 2% chlorhexidine gel; GIII: 24% EDTA gel; Negative c ontrol group: no substance was used.Then, the root canals were irrigated with 6 mL of saline solution followed by 1 min of ultrasonicpassive activation (33 20 sec). After ultrasonic activation , the canals were irrigated with 2 mLsaline. The roots were sect ioned, and the perce ntage of each chemical element present in thesamples was analyzed through chemi cal SEM-EDS microanalysis. All expe rimental groupsshowed a significantly higher percentage of chemical elements (Na and/or Cl) than the controlgroup (P < 0.03). This in vitro study has shown that, regardless of chemical solutions used evenafter the final irrigation protocol, chemical residues of d ifferent substances remained attached tothe r oot c anal wa lls. Microsc. Res. Tech. 78:495–49 9, 2015.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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This study evaluated the influence of finishing and polishing procedures and differ-ent fluoride solutions on superficial morphology and chemistry of the nanofilled composite resinSupreme XT (3M) through the EDX analysis and SEM evaluation. Circular specimens (n 5 30) of 10mm diameter and 2 mm thickness were prepared, with half of the sample assays finished and polishedwith Super-Snap1sandpaper. The experimental groups were divided according to the presence or ab-sence of finishing and polishing and solutions (arti ficial saliva, 0.0 5% of manipulated sodium fluoridesolution, Fluordent Re ach, Oral B, Fluorgard). Specimens were immersed in each respective solutionfor 1 min per day, during 60 days and stored in artificial saliva at 37 6 18C between immersion peri-ods. Topography and chemical analysis was qualitative. It was observed that specimens submitted tofinishing and polishing procedures had lower superficial degradation. Fluoride solutio ns promoted su-perficial alterations on specimens, being the highest degradation obtained with Fluordent Reach. Itca n be concluded that finishing and polishing procedures and the immersion media influence the su-perficial morphology of composite resin tested; the Fluordent Reach was the flu oride solution thatmo st affected the material’s surface.

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Composite resin is a dental material susceptible to color change over time which limits the longevity of restorations made with this material. The influence of light curing units and different fluoride mouthrinses on superficial morphology and color stability of a nanofilled composite resin was evaluated. Specimens (N = 150) were prepared and polished. The experimental groups were divided according to the type of light source (halogen and LED) and immersion media (artificial saliva, 0.05% sodium fluoride solution-manipulated, Fluordent Reach, Oral B, Fluorgard). Specimens remained in artificial saliva for 24-h baseline. For 60 days, they were immersed in solutions for 1 min. Color readout was taken at baseline and after 60 days of immersion. Surface morphology was analyzed by Scanning Electron Microscopy (SEM) after 60 days of immersion. Color change data were submitted to two-way Analysis of Variance and Tukey tests (α = 0.05). Surface morphology was qualitatively analyzed. The factor light source presented no significant variability (P = 0.281), the immersion media, significant variability (P < 0.001) and interaction between factors, no significant variability (P = 0.050). According to SEM observations, no difference was noted in the surface of the specimens polymerized by different light sources, irrespective of the immersion medium. It was concluded that the light source did not influence the color stability of composite, irrespective of the immersion media, and among the fluoride solutions analyzed, Fluorgard was the one that promoted the greatest color change, however, this was not clinically perceptible. The immersion media did not influence the morphology of the studied resin. Microsc. Res. Tech. 77:941–946, 2014. © 2014 Wiley Periodicals, Inc.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)