The Kallikrein Inhibitor from Bauhinia bauhinioides (BbKI) shows antithrombotic properties in venous and arterial thrombosis models

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Calciphylaxis: a rare but potentially fatal event of chronic kidney disease. Case report

Calciphylaxis or calcific uremic arteriolopathy is a rare cutaneous-systemic disease occurring in patients with advanced chronic kidney disease. The classical clinical picture is that of a necrotic and progressive skin ulcer of reticular pattern, mostly in the lower legs and susceptible to local infection. It is a product of mural calcification and occlusion of cutaneous and sub-cutaneous arteries and arterioles. The authors report the case of a 73-year-old male patient in his late stage of renal disease presenting severe necrotic cutaneous ulcers on lower legs followed by local and systemic infection and death due to sepse after parathyroidectomy.

Cardiovascular effects of a continuous rate infusion of lidocaine in calves anesthetized with xylazine, midazolam, ketamine and isoflurane

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Using Conservative Condylectomy for Management of a Large Osteochondroma of the Mandibular Condyle With 6-Year Follow- up

Osteochondroma is a hamartomatous proliferation of cartilaginous tissue, which is the most common benign tumor of the long bones, but is relatively rare in the maxillofacial region. Most cases of mandibular condylar osteochondroma manifest with facial asymmetry or malocclusion with limited temporomandibular joint movements. Several approaches for management of this lesion have been proposed, as conservative condylectomy technique. This procedure has been suggested a valid approach to minimize facial asymmetry, contributing to the recovery of occlusion associated with no local tumor recurrence, and without condylar reconstruction procedure. Therefore, this article aims to describe a clinical report of a true osteochondroma of the mandibular condyle in a 35-year-old patient who was successfully treated using conservative condylectomy procedure.

A Reproducible Venous Thrombosis Model in Horses Induced by the Combination of an Endothelial Lesion and Blood Flow Stasis

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Frequencies of-308G/A (TNFA) and-509C/T (TGFB1) polymorphisms in sickle cell anemia patients from Brazil

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Planejamento protético para pacientes adultos portadores de fissura labiopalatal congênita, que não obtiveram oportunidade de um tratamento reabilitador ideal: execução de casos clínicos para pacientes selecionados

Although one cannot prevent the birth of human beings with cleft palate lesions one can adopt attitudes and various procedures entirely viable to rehabilitate and recuperate these persons through a team work composed of the facilities of a hospital, physician, dentist, psychotherapist, epeech pathologist, pedagogue and a social worker. In order to reduce the suffering of these patients we took up this work to prove that even if not in an ideal manner nevertheleses in an acceptable one we can reintegrate these persons to their families, friends and social milieu, offering them more security in their social, psychic and human relationships. We have made a review of the literature during the last three decades where we found many possibilities of prosthetic recuperations which concerns esthetics, mastication and maxillomandibular relationships beyond allowing these pacients conditions to perform satisfactory the functions of deglution and speech. We have selected and executed 5 clinical cases out of 15 pacients formely choosen looking to different prosthetic plannings. We have also shown the major contribution that the osseous integrated implants can offer to the rehabilitation and recuperation of pacients whith congenitall labio palatal lesions. To simplify the understanding we tried to discuss the most varied types of prosthesis in well defined subjects having a separate approach for each of them and we still showed that the specificity of each case leads to a specific type of rehabilitation founded om esthetics, occlusion, osseous suport, edentulous space, and above all based in the common sense and Professional integrity

Contribuição ao estudo da frequência de sintomas subjetivos, relatados como queixa principal, por pacientes com disfunção craniomandibular

We surveyed subjective symptoms of 600 patients referred to the Occlusion and Craniomandibular Dysfunction Center of the School of Dentistry, Campus of São José dos Campos São Paulo, Brazil. We have only considered those symptoms reported by the patients as major complaints. Our purpose on this project was to draw a profile of the disease considering sex, age and incidence of the symptoms that presented themselves or associated with others. Findings were that we found a significant larger number of women, 82.83%, comparing with 17.17% of men. Most of the patients belonged to the third decade, followed by the fourth and second. The most frequent symptom was pain on TMJ region, 42%, followed by TMJ noises, 26.6%, facial pain, 15.5%, earache, 14.5% and headache, 12.1%. The symptom TMJ noises showed to be statistically more significant in men, while headaches, pain in the neck region and temporary locking were more frequent in women. The most frequent association between two symptoms was: TMJ noises with TMJ pain, earache with headache and TMJ pain with earache. There was no statistical difference between sexes. The most frequent association of three symptoms was: TMJ noises together with TMJ pain and pain or difficulty in chewing

Distúrbios funcionais da oclusão e sua correlação com radiografias transcranianas da articulação temporomandibular, em pacientes portadores de fissuras labiopalatais

Anamnesis, clinical examinations and temporomandibular joint transcraneal radiographs for 22 adults with cleft lip and palate were carried out in order to evaluate the occlusion and correlate it with radographic findings. The conclusions were: 72.8% of the patients have at least one sign or symptom of craniomandibular disorders (CMD); although the occlusal conditions were severely altered, most of the signs and symptoms were classified as mild; the greater frequency of the signs and symptoms occurred among women; in the radiographic evaluation, all of the assymptomatic patients had both condyles with normal contour and all of the patients with altered contour had at least one sign or symptom; the bilateral centered position of the condyles in the fossa e did not warrant the absence of signs and symptoms; some patients with bilateral condyles positioned posteriorly or caudally or even assimetrically, did not present signs and symptoms of dysfunction; the radiographic findings should be correlated with clinical findings; and a great number of patients were not observed with clinical board of C:MD caused by the occlusion. Key words: Radiography; temporomandibular joint; temporomandibular joint syndrome; cleft palate; dental occlusion

Estudo da prevalência de disfunção craniomandibular segundo o índice de Helkimo tendo como variáveis: sexo, faixa etária e indivíduos tratados ou não ortodonticamente

One hundred non-patient dentistry students aged 17 to 25, were interviewed through questionnaire and were clinically examined in order to asses the prevalence and degree of severtty of Craniomandibular Dysfunction, through indeces which are subdivided into three classes: anaminestic index, clinical dysfunction index, and occlusal index. The following variables were introduced to the original indeces: sex, age, and whether the subjects had or had not received orthodontic treatment. The results showed that 42% of the subjects presented mild subjective symptoms whereas, no one showed severe subjective symptoms. Women, as well as the older subjects, showed a higher trend to presenting more subjective complaints. Subjects, whether treated orthodontically or not, showed a similar trend to having dysfunction symptoms. Fifty-six per cent of the subjects presented some score of clinical dysfunction, 25% of them showed moderate or severe clinical dysfunction. Women showed a statistically significant higher index. The older subjects trented to have indeces with more severe degrees. Orthodontic treatment suggested to have no influence on the clinical dysfunction index. Sixty-six per cent of the subjects showed a mild occlusal index and 11% a severe occlusal index. Sex, age, and orthodontic treatment did not show any significant difference as to the presence or absence of malocclusion

Oclusão, estresse e características psicológicas como fatores etiológicos de disfunção craniomandibular

Pós-graduação em Odontologia Restauradora - ICT

Two levels of the inspired oxygen fraction in propofol-anesthetized dogs with high intracranial pressure: cardiopulmonary function

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Polishing for glass ceramics: Which protocol?

Purpose: The execution of adjustments on ceramic restorations is sometimes necessary for either correction of occlusion and/or inadequate contours or esthetical improvements. Clinically, the surfaces undergo weariness through fine grinding diamond burs which remove the superficial glazing layer. Several materials for ceramic polishing have been used in an attempt to reach a satisfactory surface smoothness. The aim of this study was to perform a literature review on different polishing protocols of several dental ceramics. Study selection: This is a literature review performed through scientific articles published between 2004 and 2012, indexed in MEDLINE, PubMed and Scielo databases. The study selected and analyzed a total of 20 relevant articles that evaluated different types of ceramics, polishing treatment and surface roughness.Results: After an extensive literature review, this study observed: 1 - after the rupture of the glazing layer due to the adjustments of the restorations, the best choice for the polishing of the surface will depend on the type of ceramics used; 2 - glazing procedure provide excellent results regarding to the superficial smoothness; however, if reglazing is impossible, either abrasive rubber cups/points or sandpaper discs followed by the use of diamond polishing pastes results in a satisfactory superficial smoothness; 3 - clinical studies that take into account the behavior of the protocols polishing are scarce and should be encouraged; 4 - the large number of variables influence the final outcome of polishing should be considered. Conclusions: The necessity in standardization of methodologies to enable a comparison among researches. (c) 2014 Japan Prosthodontic Society. Published by Elsevier Ireland. All rights reserved.

CrataBL, a lectin and Factor Xa inhibitor, plays a role in blood coagulation and impairs thrombus formation

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Thickness and marking quality of different occlusal contact registration strips

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)