Avaliação de qualidade de vida dos pacientes submetidos à cirurgia de amputação abdominoperineal do reto com colostomia abdominal ou colostomia perineal

Pós-graduação em Pesquisa e Desenvolvimento (Biotecnologia Médica) - FMB

Fatores socioeconômicos e comportamentais associados à adiposidade abdominal de adultos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Avaliação funcional e histológica do enxerto tubular de matriz acelular arterial heteróloga como substituto da uretra em coelhos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Avaliação da função renal em pacientes submetidos à colecistectomia ou correção de hérnia de hiato por via laparoscópia

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Avaliação moroflógica e estereológica comparativa do implante da tela de polipropileno e peritônio de pacas (Cuniculus paca, L. 1766) na correção de defeitos da parede abdominal de ratos Wistar

Pós-graduação em Cirurgia Veterinária - FCAV

Obtenção e processamento de matrizes tridimensionais de colágeno e implantação em parede abdominal de eqüinos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Obstrução intestinal experimental em equinos: parâmetros clínicos e laboratoriais

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Implantação videoassistida de sonda intracecal: estudo experimental em equinos

Pós-graduação em Medicina Veterinária - FMVZ

Efeito da orquidectomia, seguida ou não de reposição com testosterona, sobre as respostas vasomotoras de veias de rato à estimulação de receptores adrenérgicos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Análise da segurança oncológica na cirurgia de Wetheim-Meigs via videolaparoscópica comparada à via laparotômica

Pós-graduação em Ginecologia, Obstetrícia e Mastologia - FMB

Avaliação da função ovariana pós histerectomia total abdominal em mulheres no menacme

Pós-graduação em Ginecologia, Obstetrícia e Mastologia - FMB

Turnover isotópico do carbono em tecidos corporais de suínos: músculos, fígado, gordura abdominal, plasma, casco e costela

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Avaliação dos distúrbios metabólicos de pacientes obesas, grau III, antes e depois da cirurgia bariátrica

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Serum cystatin C is a sensitive early marker for changes in the glomerular filtration rate in patients undergoing laparoscopic surgery

OBJECTIVE: Pneumoperitoneum during laparoscopy results in transient oliguria and decreased glomerular filtration and renal blood flow. The presence of oliguria and elevated serum creatinine is suggestive of acute renal injury. Serum cystatin C has been described as a new marker for the detection of this type of injury. In this study, our aim was to compare the glomerular filtration rate estimated using cystatin C levels with the rate estimated using serum creatinine in patients with normal renal function who were undergoing laparoscopic surgery. METHODS: In total, 41 patients undergoing laparoscopic cholecystectomy or hiatoplasty were recruited for the study. Blood samples were collected at three time intervals: first, before intubation (T1); second, 30 minutes after the establishment of pneumoperitoneum (T2); and third, 30 minutes after deflation of the pneumoperitoneum (T3). These blood samples were then analyzed for serum cystatin C, creatinine, and vasopressin. The Larsson formula was used to calculate the glomerular filtration rate based on the serum cystatin C levels, and the Cockcroft-Gault formula was used to calculate the glomerular filtration rate according to the serum creatinine levels. RESULTS: Serum cystatin C levels increased during the study (T1 = T2T3; p<0.05). The calculated eGlomerular filtration rate-Larsson decreased, whereas the eGlomerular filtration rate-Cockcroft-Gault increased. There was no correlation between cystatin C and serum creatinine. Additionally, Pearson's analysis showed a better correlation between serum cystatin C and the eGlomerular filtration rate than between serum creatinine and the eGlomerular filtration rate. CONCLUSION: This study demonstrates that serum cystatin C is a more sensitive indicator of changes in the glomerular filtration rate than serum creatinine is in patients with normal renal function who are undergoing laparoscopic procedures.

Alterations of the gastric stump and not resected stomach mucosa after truncal vagotomy in rats

PURPOSE:To evaluate morphological changes of the gastric stump and not resected stomach mucosa after the completion of truncal vagotomy.METHODS:Eighty male Wistar rats were divided into four groups: CT, TV, RY and RYTV. In CT group, abdominal viscera were manipulated and the abdominal cavity was closed, in TV vagal trunks were isolated and sectioned, in RY a partial Roux-en-Y gastrectomy was performed and in RYTV the vagal trunks were sectioned and a partial Roux-en-Y gastrectomy was performed. At the 54th week after surgery, the rats were euthanized. The findings were submitted to histological analyses.RESULTS:None macroscopic or histological alterations in groups TV and CT was observed. Specimens from RY and RYTV groups did not show alterations in the gastric stump mucosa. At the jejunal side of the gastroenterostomy we found shallow ulcerative lesions always single, well-defined and with variable diameter 3 to 6 mm, six times in the RY group and none in the RYTV group (RY>RYTV, p=0.008). Neoplastic or preneoplastic lesions were not diagnosed in all groups.CONCLUSION:Truncal vagotomy is a safe and non-carcinogenic method in not resected and partially resected stomach.