Expressão gênica e proteica e cinética celular no processo inflamatório induzido pela Helicobacter pylori antese após terapia de erradicação

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Efeito da infecção pelo vírus da febre amarela no mecanismo de splicing celular

Pós-graduação em Microbiologia - IBILCE

Variação e gramaticalização no uso de preposições em contextos de verbos de movimento no português brasileiro

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Proposta de um protocolo de terapia celular para o tratamento da doença pulmonar obstrutiva crônica

The main feature of pulmonary emphysema is airflow obstruction resulting from the destruction of the alveolar walls distal to the terminal bronchioles. Existing clinical approaches have improved and extended the quality of life of emphysema patients. However, no treatment currently exists that can change the disease course and cure the patient. The different therapeutic approaches that are available aim to increase survival and/or enhance the quality of life of emphysema patients. In this context, cell therapy is a promising therapeutic approach with great potential for degenerative pulmonary diseases. In this protocol proposition, all patients will be submitted to laboratory tests, such as evaluation of heart and lung function and routine examinations. Stem cells will be harvested by means of 10 punctures on each anterior iliac crest, collecting a total volume of 200 mL bone marrow. After preparation, separation, counting and labeling (optional) of the mononuclear cells, the patients will receive an intravenous infusion from the pool of Bone Marrow Mononuclear Cells (BMMC). This article proposes a rational and safe clinical cellular therapy protocol which has the potential for developing new projects and can serve as a methodological reference for formulating clinical application protocols related to the use of cellular therapy in COPD. This study protocol was submitted and approved by the Brazilian National Committee of Ethics in Research (CONEP - Brazil) registration number 14764. It is also registered in ClinicalTrials.gov (NCT01110252). (c) 2013 Sociedade Portuguesa de Pneumologia. Published by Elsevier Espana, S.L. All rights reserved.

Fragmentos da pedagogia de Cristiane Paoli Quito: tiros de movimento-imagem

Pós-graduação em Artes - IA

Avaliação óptica, ultraestrutural e expressão de proliferação celular da mucosa entérica de frangos de corte suplementados com glutamina e ácido glutâmico

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Expressão da proteína nuclear de proliferação celular (PCNA), da B-Catenina e do Agnor, na etapa inicial do processo de carcinogênese quimicamente induzido pelo DMBA, em borda lateral de língua de hamsters sírio dourado(Mesocricetus auratus)

The oral cancer model in hamsters shows many simílarities with developmental oral cancer in humans. The proliferating capacity is one the most characteristics of neoplásica ce/Is and detection of these ce/Is allow us, throughout of its counting, to achieve an estimated tumour growing index, with a consequent repercussion about prognostic and in the treatment of those lesions. 40 golden Syrian hamsters, both genders, aged between two to six mouth and weight 150g in average were used. The left síde of tangue of each animal was painted for eight consecutive weeks, with a solution of DMBA. Tongues were removed, fixed in 10% buffered fonnal solution. The histological slides were stained by AgNOR technique and by PCNA and β-catenin immunohistochemical antibodies. Statistical analyzes were performed by ANOVA one-way test and Tukey test. We may conclude that an association between AgNOR and PCNA might indicate the higher proliferating activity of the analyzed celIs. The experimental carcinogenesis model in hamster tongue is an available methodology for immunohistochemistry study. And finally, PCNA and β-catenin immunohistochemical antibodies may be used to analyze possible premalignant areas in oral leukoplakia

Imunidade celular em caninos neonatos - do nascimento ao 45° dia de idade

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

O movimento interdisciplinar em Ciência da Informação: uma reflexão epistemológica

The complexity of interdisciplinarity as a category of analysis in contemporary discourses gain evidence. In information science, the practice of integration of scientific discourse aims, among others, the establishment and consolidation of their identity as a scientific field. Thus, the study aims to reflect on the epistemological status of information science as an interdisciplinary scientific field. To this end, we discuss the interdisciplinarity in the sciences and, under this understanding, address the interdisciplinary movement in Information Science and the real fruits of this process nowadays. The reflections undertaken in this study indicate the need to forward the discussions on interdisciplinarity as a focal point with the configuration of the related fields and their real benefits for Information Science.

Relação entre incapacidade funcional, amplitude de movimento e dor em indivíduos com e sem lombalgia

Introduction: Low back pain is characterized as pain between the inferior margins of the ribs to the gluteal fold, reaching about 80% of the population throughout life. Its repercussions can affect the functionality of the subjects in their daily activities. The aim was to investigate whether a relation between symptoms of pain in the lumbar region with range of motion and functional disability. Methods: We interviewed 101 subjects with a mean age of 22.61 ± 4.06 years, these 50 participants were 51 low back pain and other complaints of back pain. OS subjects were assessed for pain by Visual Analogue Scale (VAS), mobility Lumbar Schöbber test (TS), flexibility for the Test Sit and Reach (TSA) and feature the Oswestry Disability Index (IOI). For data analysis we used GraphPad Prism 5, the significance level was set at p ≤ 0.05. Results: No significant differences were found for the comparison between the TSA of the subjects with and without pain (p = 0.25), nor to compare the performance of the TS for the subjects with and without pain (p = 0.18). Conclusion: It is concluded that in cases evaluated the range of motion has no significant link with the pain but the pain in turn directly influence the functionality of them.

Avaliação goniométrica da amplitude de movimento do ombro de crianças praticantes de beisebol

Introduction: Baseball is a Sport disputed by two teams composed at least by nine players which compete between themselves in a game of six innings in the amateur game, for children up to 10 years old. Objective: The objective is to compare the movement degrees of the shoulder joint between the dominant and the non dominant shoulder. Methods: Eleven male subjects were assessed (8,63 ± 0,67 years old) whom practiced baseball at the Nikkey Club of the city of Marília – SP. All of the subjects were assessed by the same examiner, whom measured the range of motion (ROM) of both glenohumeral joint. The Student t test was used for the comparison of the shoulders, with level of significance of 5% (p≤0,05). Results: The subjects presented significant differences on the external rotation movement (p= 0,014) between the dominant shoulder (63,63 ± 12,92°) and the non dominant shoulder (55,45 ± 16,27°), and in the internal rotation movement (p= 0,001) between the dominant shoulder (32,90 ± 5,68°) and the non dominant shoulder (40,72 ± 5,74°). Conclusion: The results obtained in this study, on the experimental conditions utilized, allow us to conclude that the practice of baseball influence the range of motion of external rotation and internal rotation of the dominant shoulder, with increased external rotation, and a decreased internal rotation, provoking instability of the shoulder joint.

Ampliação do Ensino Fundamental para nove anos: entre as normatizações da política educacional, o movimento teórico e as representações sociais dos profissionais da escola pública

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

O movimento negro mineiro e a esfera pública: desafios e perspectivas para um Fórum Intergovernamental de promoção da igualdade racial

Pós-graduação em Ciências Sociais - FCLAR