Influência da adição de bioactive glass na liberação de íons do cimento de ionômero de vidro modificado por resina

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Estudo de comportamento térmico e de biodegradação de PHBV4% modificado com hidroxiácido

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Avaliação da biocompatibilidade e do processo de reparo dos cimentos endodônticos: MTA Fillapex, Endo-CPM-Sealer e Sealapex

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Avaliação de propriedades físicas, químicas e biológicas de cimentos Portland associados a radiopacificadores micro e nanoparticulados

Pós-graduação em Odontologia - FOAR

Compósitos ppticamente transparentes baseados em celulose bacteriana e boehmita, siloxano e/ou sistema boehmita-siloxano

The present invention comprises composites with multifunctional characteristics, being capable of substituting glass, with significant advantages, with particular emphasis on flexibility, for a variety of applications such as, for example, display screens and others. Among other aspects, the product that constitutes the object of the invention is particularly characterized by rendering bacterial cellulose transparent, in addition to being flexible, biocompatible and able to replace glass in 100% of possible applications. Among other aspects, the development of the composites according to the present invention allows an effective increase in optical transmission, enabling an optical transmission of more than 90%, such transparency being necessary, equally, for the development of medical devices, for example.

Avaliação macroscópica e microscópica de implante de Biomembrana em estômago de coelhos (Oryctolagus cuniculus)

In this study, biomembrane of natural latex was utilized to replace a section of the stomach wall of New Zealand rabbits, adult and non-castrated males (n=12), in order to evaluate the tissue repair process in regards to its biocompatility, scar formation ability and possible complications. The animals were euthanized at fifteen, 30 and 60 days post operation, by use of sodium thiopental (200mg kg-1), followed by macroscopic and histopathological analysis of the implant interface with the native tissue. Macroscopically, at fifteen, 30, and 60 days post operation adherence was observed in the serosal wall. At 60 days post operation, the biomembrane is not in the stomach. Under light microscopy, at fifteen and 30 days, discontinuity of muscle layer and mucosa layer, and presence of polimorfonuclear population of inflammatory cells was observed. New vessels and muscle fibers were observed. At 60 days, the mucosa and muscle layers were complete reconstituted. The implants were biocompatible and had provided the mainframe for orientation and development of the tissue layers through repairing processes, thus reestablishing the organ structure.

Aspecto radiológico e macroscópico de matriz óssea mineralizada heteróloga fragmentada e polimetilmetacrilato autoclavados em falha óssea de tíbia de coelho

A segmental defect of 6mm diameter was performed in the medial metaphyseal region of the tibia of 12 rabbits. For the bone defect reconstruction there was implanted a combination of micro and macro fragments of heterologous fragmented cortical bone matrix preserved in glycerin (98%) and polymethylmethacrylate, both autoclaved. Radiological and macroscopic evaluation was performed at 30, 60, 90 and 120 days. Adhesion in relation to time of the micro and macro composites to the recipient bed was observed in 100% of the cases. This showed that this implant is biologically biocompatible, since it promoted bone defects repair, with no signs of infection, migration and/or rejection. In this way, this implant can be classified as one more option of substitute to fill large bone defects.

Corrosão e tribocorrosão de novas ligas Ti35Nb5Zr e Ti35Nb10Zr em saliva artificial

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Caracterização e avaliação da citocompatibilidade de nanocompositos baseados em celulose bacteriana e fibroína para aplicação em regenração tecidual

Pós-graduação em Ciências Odontológicas - FOAR

Biomaterials from blends of fluoropolymers and corn starch-implant and structural aspects

The development of polymeric blends to be used as matrices for bone regeneration is a hot topic nowadays. In this article we report on the blends composed by corn starch and poly(vinylidene fluoride), PVDF, or poly(vinylidene fluoride-trifluoroethylene), P(VDF-TrFE), to obtain biocompatible materials. Blends were produced by compressing/annealing and chemically/structurally characterized by micro-Raman scattering and Fourier transform infrared (FTIR) absorption spectroscopies, dynamic mechanical analysis (DMA) and scanning electron microscopy (SEM), besides in vivo study to evaluate the tissue response. Vibrational spectroscopy reveals no chemical interaction between the polymers and starch, absence of material degradation due to compressing/annealing process or organism implantation, and maintenance of a and ferroelectric crystalline phases of PVDF and P(VDF-TrFE), respectively. As a consequence of absence of interaction between polymers and starch, it was possible to identify by SEM each material, with starch acting as filler. Elastic modulus (E') obtained from DMA measurement, independent of the material proportion used in blends, reaches values close to those of cancellous bone. Finally, the in vivo study in animals shows that the blends, regardless of the composition, were tolerated by cancellous bone. (C) 2013 Elsevier B.V. All rights reserved.

Stimuli-Responsive Biointerface Based on Polymer Brushes for Glucose Detection

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Bending of Layer-by-Layer Films Driven by an External Magnetic Field

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Light-emitting diode effects on combined decellularization of tracheae. A novel approach to obtain biological scaffolds

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

A castor oil-containing dental luting agent: effects of cyclic loading and storage time on flexural strength

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Resposta tecidual induzida por Biodentine™e MTA Branco em subcutâneo de ratos

Pós-graduação em Odontologia - FOAR