Identificação de bactérias láticas e otimização da produção de ácido lático

O objetivo deste trabalho foi identificar o micro-organismo Y15C previamente isolado no laboratório de microbiologia industrial, da UNESP de Rio Claro, utilizando técnicas bioquímicas, além de otimizar a produção de ácido lático por meio de fermentação batelada simples e batelada alimentada. Considerando o potencial do micro-organismo para a produção de D(-) ácido lático, com 100% de pureza, isômero usado na síntese de polímeros empregados na produção de diversos materiais resistentes e biodegradáveis, foi feita a otimização do meio de cultura, tendo como fonte de carbono a manipueira. A manipueira por ser um resíduo do processamento da mandioca que contém grande quantidade de amido e quando hidrolisado pode ser uma fonte de carbono de baixo custo, quando utilizado pelo micro-organismo. O isolado Y15C foi identificado como Lactobacillus delbrueckii ssp delbrueckii, por meio de testes bioquímicos. Em relação à otimização dos parâmetros de fermentação, usando planejamento experimental, observou-se que a adição de componentes ao meio de cultivo, assim como a variação da temperatura não aumentou significamente a produção de ácido lático. Desta forma optou-se por trabalhar com as menores concentrações de AMM (1,6 mL/L) e citrato (0,96 g/L) e maior temperatura (43,4ºC). Para que haja aumento na produção de ácido lático podem ser realizados diversos tipos de fermentações, no caso deste trabalho foram comparados dois tipos de fermentação, batelada simples e batelada com alimentação constante. A maior concentração de ácido lático (41,6 g/L) foi observada que quando utilizada fermentação do tipo de fermentação em batelada... (Resumo completo, clicar acesso eletrônico abaixo)

Cálculo das funções de anisotropia e radial de dose para braquiterapia com semente de 192Ir em diferentes materiais de interesse em radiologia com o auxílio do programa baseado no método de Monte Carlo MCNPX

The brachytherapy braquiterapia is an x-ray modality radiotherapy in which stamped or halfstamped radioactive sources in format of seeds are used, wires or to one short distance, in contact or implanted to the fabric to be treated. All the treatment modalities require a previous planning. The formalism recommended for calculation of dose was considered by the AAPM for the first TG-43 Report. In it distributions of dose of isolated seeds measured and calculated by Monte Carlo method in water instead of with models half-empiricists. In this work we in accordance with present some preliminary results of the calculation of functions of radial anisotropy and of dose in the distance for seed of 192Ir, wide used in brachytherapy treatments of high tax of dose (HDR), with the aid of the program based on the Monte Carlo method MCNPX v2.50 (Mount Carlo N ParticleeXtended). The materials chosen in the simulation beyond water, had been MS20 and estriado muscle

Atividades exploratório-investigativas em sala de aula de cálculo I com uso de tecnologia

This study presents the results from a qualitative resource, based on research-action methodology, which examined the innovate teaching practices implementations in the Calculus I during 2011 year. The analysis of collected data from three used sources – an initial questionnaire, an exploratory-investigative classroom, and an interview with some students at the end of the second semester – reveals that the students had appropriated of the technological recourses, using it as a tool to look for the knowledge. The investigative activities with the use of information technologies made the use of multiple representations in solving mathematical tasks, making the transition of numerical, algebraic and geometrical results possible for the students when they have looking for validation of their hypotheses and conjectures during mathematical problems solving. This works helped in the insertion of new practices in the discipline, and their results validate the proposal presented by the teacher, which is the discipline of Calculus use, whose character is strongly linked to the training content of the student, as a discipline whose can contributed to the pedagogical formation of the graduation student, leading him to know the Mathematical Education possibilities, specially the Mathematical Investigation - Solving Problems, in the outlook of dialogued classes where the teacher assumes the facilitator role and where the students become actives in their pursuit of knowledge

Controle de qualidade em radioterapia: dosimetria de fótons em acelerador linear – Mevatron MXT

The treatment of a tumor with ionizing radiation is an ongoing process with well differentiated stages. These ones include the tumor diagnosis and location, the decision on the treatment strategy, the absorbed dose planning and calculation, the treatment administration, the absorbed dose verification and the evaluation of results in short and long terms. The quality of a radiotherapy procedure is closely linked to factors that may be classified as clinical, such as the diagnosis, the tumor location, the treatment strategy chosen and the continuous treatment reassessment; dosimetric or physical, such as the uncertainty in the dose calculation, its optimization and verification, the suitability of the equipment to provide a radiation beam consistent with the treatment planning; finally, others which are related to the practical application of radiotherapy treatment and the handling of the patient. In order to analyze the radiotherapy quality, one should realize that the three aspects (medical, physical or dosimetric and practical application) should be considered in a combined way. This means that numerous actions of the radiotherapists, medical physicists and technicians in radiotherapy should be held jointly and their knowledge level will significantly affect the treatment quality. In this study, the main physical parameters used in dosimetry are defined as well as determined experimentally for a linear accelerator Mevatron - MXT. With this, it is intended to provide recommendations for the physical aspects of Quality Assurance (QA) in the radiotherapy treatments, and these will usually be applied by professionals in Medical Physics. In addition to these instructions, it is recommended that additional texts are prepared to address in detail the clinical aspects of the treatments QA

Otimização da produção de queratinase por Bacillus amyloliquefaciens

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Otimização da estrutura metalica para um carro alegórico

Carnival is a unique opportunity for the associations demonstrate the community’s annual work and the float is a major component of this celebration, responsible for pitch the samba using allegories and carry important figures. The excess weight of the floats which are mostly manufactured from truck and bus structures requires larger amount of people to push the vehicle in addition to increased efforts on the steering systems, suspension and wheels, raising the probability of breakage and loss of one year work. The objective of this study is to use the concepts of strength of materials combined with computer simulation to obtain a structure that has the lowest possible weight without compromising the safety of transported components and that is also easy to manufacture, drive and store

Influência de software de otimização de corte no rendimento de serraria da região sudoeste paulista

This study aimed to analyze the increase of yield provided by a software optimization cutting in a pine sawmill, located at southwest region of São Paulo, city of Itapeva. First were measured 10 logs that were processed by conventional sawing system by measuring the volume of products in the process output. Then using a cutting optimization software, that generated cuts diagrams, 10 logs, from 25 to 26 cm diametrical class, were processed by sawing system optimized. For the conventional sawing, the value found to yield was 41.80%, whereas for the unfolding optimized showed the value of 61.79%, resulting in a difference of 19.99%. This study shows that there is room for significant improvement of performance in sawmills sawing with the use of optimization software as the employee at work

Otimização do braço inferior da suspensão dianteira do veículo Baja utilizando o método dos elementos finitos

Mass reduction coupled with the mechanical performance in service has been the goal of many projects related to the transport area, considering the advantages that mass reduction can bring. However, make a simple material substitution without design a new geometry to corroborate for the best component performance, often makes the replacement unviable. In this study, it was investigated the advantages of replacing the prototype BAJA SAE front suspension lower arm of Equipe Piratas do Vale de BAJA SAE - Universidade Paulista, Campus Guaratinguetá, actually produced with steel, for a new component made of carbon fiber composite. The new geometry has been developed to provide the best possible performance for this component and your easy manufacturing. The study was done using the 3D modeling tools and computer simulations via finite element method. The first stage of this work consisted on calculation of the estimated maximum contact force tire / soil in a prototype landing after jump at one meter high, drop test in the laboratory with the current vehicle, current front suspension lower arm 3D modeling, finite element simulation and analysis of critical regions. After all current component analysis, a new geometry for the part in study was designed and simulated in order to reduce the component mass and provide a technological innovation using composite materials. With this work it was possible to obtain a theoretical component mass reduction of 25,15% maintaining the mechanical strength necessary for the appropriated component performance when incited

Otimização de procedimentos de controle de qualidade em equipamentos radiográficos convencionais do Instituto de Eletrotécnica e Energia - USP

Radiography is currently an important method of diagnosis, both medical, dental and veterinary. The image in this type of survey is obtained using an X-ray beam, where the radiologist can possibly view structures of interest. It isn't always possible to get the desired images due to various factors, such as equipment limitations. The Administrative Law 453/98, the State Resolution SS 625/94, and other standards require testing and quality control acceptance limits that guarantee a good performance of the equipment for the security and quality of care, giving service users greater effectiveness in exams. This study were performed in the accompaniment of testing procedures for quality control established by Administrative Law 453/98 in several X-ray equipment to make a comparison and optimization in the descriptions of the procedures used by the Institute for Electrical Energy and the University of São Paulo (IEE / USP / SP).The optimization of the procedures were performed with the aid of a current literature, the Resolution 453/98, State Resolution SS 625/94 and other international standards. On this basis it was possible to observe the importance of regular monitoring of tests for an update, following the technological development of instruments used in the service

Estudo de doses e otimização de carta técnica na transição de radiologia convencional para computacional em diagnósticos veterinários

This project aims the verification of doses in canines and felines to chest and coxal exams due to the transition from screen-film to computed radiography system. It also seeks a possible optimization of the new techniques employed in this new system. The study was carried out in Diagnostic Imaging service in Hospital Veterinário da Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo using a conventional x-ray equipment. Initially, data about the physical characteristics of animals and the technique currently used in computed radiography was collected for each of 80 chest and 16 coxal X-ray examinations. The animals were divided into different groups according to the body weight. For each group, were calculated the averages of each item: thickness of the region to be imaged, voltage, current, exposure time, current-time product, size of film used, presence or absence of bucky and focus (small or large). The techniques have been reproduced in phantoms (representative of the thickness of the animal) in order to collect the air kerma entrance. Based on the average of intermediate size M group (weights less than 5 kg for cats and from 10.1 kg and 20 kg for dogs) analysis of image quality using three devices test patterns were made consisting of the evaluation of spatial resolution, low-contrast resolution and contrast-detail. In general, the results showed the dose animals decreased with the use of computed radiography and was possible to preliminary optimization of some techniques used currently in CR