Interação entre as vias de sinalização de receptores serotoninérgicos e Β-adrenérgicos em artéria femoral de ratos

Fundamento: A doença coronária tem sido amplamente estudada em pesquisas cardiovasculares. No entanto, pacientes com doença arterial periférica (DAP) têm piores resultados em comparação àqueles com doença arterial coronariana. Portanto, os estudos farmacológicos com artéria femoral são altamente relevantes para a melhor compreensão das respostas clínicas e fisiopatológicas da DAP. Objetivo: Avaliar as propriedades farmacológicas dos agentes contráteis e relaxantes na artéria femoral de ratos. Métodos: As curvas de resposta de concentração à fenilefrina contrátil (FC) e à serotonina (5-HT) e os agentes relaxantes isoproterenol (ISO) e forskolina foram obtidos na artéria femoral de ratos isolada. Para as respostas ao relaxamento, os tecidos foram contraídos com FC ou 5-HT. Resultados: A potência de classificação na artéria femoral foi de 5-HT > FC para as respostas contráteis. Em tecidos contraídos com 5-HT, as respostas de relaxamento ao isoproterenol foram praticamente abolidas em comparação aos tecidos contraídos com FC. A forskolina, um estimulante da adenilil ciclase, restaurou parcialmente a resposta de relaxamento ao ISO em tecidos contraídos com 5-HT. Conclusão: Ocorre uma interação entre as vias de sinalização dos receptores β-adrenérgicos e serotoninérgicos na artéria femoral. Além disso, esta pesquisa fornece um novo modelo para estudar as vias de sinalização serotoninérgicas em condições normais e patológicas que podem ajudar a compreender os resultados clínicos na DAP.

Evaluation of dietary intake of calcium in adult subjects with idiopathic arterial hypertension

The calcium-intake relationship with other alimentary and anthropometric variables was investigates in a group of 60 adult (19-75 year-old) subjects, 50 females and 10 males, with essential arterial hypertension (DAP > 90 mmHg). The calcium intake was assessed by three different protocols: 24-hour food intake recall, food-frequency questionnaire and 3 day self-food intake register, repeated along with anthropometric measurements on three different occasions (2-15 month-intervals). The calcium intake assessed by the three methods, as well as the anthropometric data, were statistically similar on all three occasions. The mean data were then compared with those form the control, composed of 75 healthy subjects matched with the hypertensive group by age and sex. The patients ingested less calcium (mean +/- SD) than the controls on the daily (517 +/- 271 x 740 +/- 353 mg/d) and body-weight (8.1 +/- 5.0 x 11.4 +/- 5.9 mg/kg/d) basis. Among the males the calcium intake was the only difference found between groups and could be attributed to the lower intake of calcium-rich foods. The hypertensive females showed also higher lean-body mass (Body-mass index and arm muscle circumference). Thus the calcium intake discriminated both groups being associated with changes in other nutritional parameters only in females.

Manejo da fertilização NK em plantio de eucalyptus urophylla em solo de cerrado

Pós-graduação em Agronomia - FEIS

Variabilidade espacial de atributos dendrométricas do eucalipto e de um neossolo quartzarênico a partir da aplicação de calcário ou lama de cal + oxyfertil

Pós-graduação em Agronomia - FEIS

Adubação fosfatada em variedades de cana-de-açúcar cultivadas em ambiente restritivo de cerrado

Pós-graduação em Agronomia - FEIS

Avaliação do desempenho de dois monitores oscilométricos portáteis na estimativa da pressão arterial direta em gatos anestesiados com isofluorano

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Interferência do caruru-roxo no crescimento e na produtividade da pimenta dedo-de-moça

Pós-graduação em Agronomia (Produção Vegetal) - FCAV

Avaliação da qualidade da madeira de cinco espécies de Pinus destinadas à produção de celulose

Pós-graduação em Ciência Florestal - FCA

Influences of the harvest season on analytical characteristics of syrah grapes and wines produced in the northeast region of Brazil

The present study evaluated the main physical and chemical characteristics of Syrah grapes, coming from the tropical region of São Francisco river valley, harvested at different times and their relationship with analytical characteristics of resulting wines. Grapes came from the first half of 2009 harvest, collected at Casa Nova - Bahia, a semi-arid and hot region, comprising an interval from 84 days after pruning (84 dap) to the beginning of grape over-ripening, 133 days after pruning (133 dap). Harvests at 84, 91, 98, 105, 112, 119, 126 and 133 dap, were analyzed for pH, soluble solids and acidity in grapes, which were then processed for wine production. Maximum sugar/acidity ratio (s/a = 56) were observed in grapes harvested between 126 and 133 dap, coincided with the highest concentration of anthocyanins (851 mg L-1 ) and total tannins (2.6 g L-1 ) in the resulting wines, indicating that grapes collected between 126 and 133 dap showed the best potential for winemaking in the tropical climate of São Francisco river valley. This result was confirmed by the analytical characterization of wines, that, between 126 and 133 dap, showed 12.8% alcohol, 31 g L-1 dry extract, 5.6 g L-1 ashes and a TPI of 58, using only one pumping per day, for 5 days maceration. Syrah grapes considered in the present work presented a good evolution of maturation, and grapes harvested between 126 and 133 days after pruning, showed the best oenological potential for the development of red wine. The use of pH and soluble solids appeared useful parameters in the estimation of maturation degree and quality potential of grapes for winemaking.

Carbohydrates, growth and production of -roxo de valinhos- fig tree in initial development under irrigation management

The carbohydrates translocation and consequently growth and production of fig tree (Ficuscarica L.) vary according to the different management on cultivation conditions. The aim of this study was to evaluate the changes in the levels and total carbohydrates accumulation together with growth and “Roxo de Valinhos” fig trees production onimplementation of orchards in initial phase, cultivated with and without irrigation. We adopted a factorial arrangement (2 x 7) with four repetitions distributed in installments (with and without irrigation) subdivided in time (collect time). Destructive analyzes were performed at 40, 80, 120, 160, 200, 240 and 280 days after pruning (DAP) and are measured: stem diameter and branch, stem length and branch, number of leaves, internodes and fruit. Subsequently, the plant parts were sectioned to obtain the leaf area, length and roots volume, fresh and dry matter weight. The number, weight and total productivity of fruits were evaluated. The media of all growth attributes and production characteristics were higher in treatments with water irrigation. The total carbohydrate content was higher at 120 and 160 DAP and the carbohydrates accumulation was increasing for most institutions over the plants development, except for the leaves that showed a decrease in the levels at 160 DAP. The fruits showed greater carbohydrates accumulation in relation to the other evaluated organs.

Demarcação da madeira juvenil e adulta de Corymbia citriodora

This paper had the objective of determining the transition regions between the juvenile and mature wood of Corymbia citriodora (Eucalyptus citriodora) of 29 years of age from the Experimental Station of Forest Science (EECFA-LCF/ESALQ-USP), located in Anhembi, in the State of São Paulo. The regions of juvenile and mature wood were characterized through anatomical studies - axial fiber length - following the recommendations of the International Association of Wood Anatomists (1989) using disks at the DBH of the trees. The measurements of fiber length were made in equipment for acquisition, diagnosis and image analysis. Five slices were made for every centimeter, in the radial direction and six fiber lengths per slice were measured, producing 30 measurements per sample region. In the total, 1740 lengths of fiber were measured in three disks that were studied. Results indicate a trend of accentuated and linear increase for the length of fibers, from the pith to 11 cm of radial of about 79%. Between 12 cm and 19 cm of the radius, fibers length remained almost constant, and from that point on, the fiber length tended to slightly increase to the bark. It can be concluded that for these trees, at this height of sampling, when the tree has 29 years of age, the extension of the juvenile wood goes up to 52% of its radius.

Mobilização do solo, velocidade de infiltração de água e taxa de cobertura do solo na grama esmeralda, sob manejos mecanizados

The excessive compaction of the soil observed in sod production systems, affects the physical attributes of the soil, which can influence the water infiltration into the soil and hence the rate of soil cover by turfgrasses and time of the sod production. To minimize the effects of soil compacting, some producers use soil preparation equipment that raises the soil on the surface but does not cause excessive roughness which may harm the quality of the sod. Thus, the aim of the present study was to evaluate the infiltration rate and soil cover rate due to different management mechanized in the zoysiagrass sod production. The experimental design had random plots and four replications. The treatments consisted of five mechanized managements of soil: witness (without the use of equipment); coulter blade disc harrow used once (1CB), coulter blade disc harrow used twice (2CB), surface chisel used once (1C), surface chisel and coulter blade disc harrow used once (1C + 1CB). The treatments with 2CB and 1C + 1CB provided greater basic water infiltration speed in the soil and higher rate of soil cover by the turfgrass. The rate of soil cover by turfgrass is positively correlated with water infiltration rate at 133 and 226 DAP, demonstrating the influence of managements used in zoysiagrass sod production and the increment in the infiltration rate of water. Soil preparation utilizing coulter blade disc harrow used twice or surface chisel and coulter blade disc harrow used once is recommended under the conditions this study was done.

Disponibilidade hídrica e utilização do nitrogênio em cana-de-açúcar irrigada por gotejamento subsuperficial

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Tamanho de parcelas experimentais e seleção simultânea de caracteres em progênies de Eucalyptus camaldulensis Dehnh

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)