231 resultados para Débito cardíaco


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O medo é uma emoção natural do ser humano, podendo representar um diferencial importante em relação à performance motora, especialmente quando se focaliza o ambiente das atividades físicas no Circo, mais particularmente do Cirque Du Soleil, por ser este bastante rico em desafios corporais. O Cirque Du Soleil é um império de entretenimento que tem sede nas cidades de Montréal e Quebec no Canadá e a transgressão do natural e a realização do impossível por meio do corpo humano representam as características básicas e marcantes desse espetáculo circense, carregado de emoções. Sendo assim, o objetivo do estudo centra-se em investigar a presença ou ausência do medo nas performances de um artista do Cirque Du Soleil, identificando seu significado e as maneiras com que este lida com esta emoção, antes e após o espetáculo e durante os treinos e ensaios. O estudo, de natureza qualitativa, foi desenvolvido em duas etapas, sendo a primeira referente a uma revisão de literatura acerca das temáticas propostas e a segunda relativa a uma pesquisa exploratória, utilizando-se como instrumento para coleta de dados um questionário contendo perguntas abertas, aplicado a uma amostra intencional composta por 1 integrante do Cirque Du Soleil, com o domínio do idioma português. Os dados foram analisados descritivamente, por meio da Técnica de Análise de Conteúdo Temático e indicam que artistas circenses sentem medo, ansiedade e nervosismo, além de alterações corporais, como aceleração do batimento cardíaco, antes de apresentações e diante do aprendizado de novos movimentos, que podem causar acidentes, tendo em vista que interferem na performance. O sujeito tenta controlar essas reações com pensamentos positivos, uma vez que entende que o medo é fruto de algo fictício proveniente da sua mente e utiliza a respiração para se acalmar. Esses resultados ...(Resumo completo, clicar acesso eletrônico abaixo)

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The use of multimodal neuroimaging techniques has been helpful in the investigation of epileptogenic zone in patients with refractory epilepsies. This work aims to describe an ictal event during EEG-fMRI performed simultaneously in a 39-year-old man with refractory epilepsy. The EEG data were recorded at a sampling rate of 5 kHz, using a BrainAmp (BrainProducts, München, Germany) amplifier, with 64 MR (magnetic resonance) compatible Ag/AgCl electrodes. MR images were acquired using a 3T scanner in 3 sequences of 6 minutes of echo-planar images (EPIs), with TR = 2s, being the last sequence stopped after the ictal event. The EEG was corrected for gradient and pulse artifacts using the Brain Vision Analyzer2 software (BrainProducts), and the functional images were realigned, slice-timing corrected, normalized and smoothed. The start of the ictal changes was used for the evaluation of the BOLD response in MR images, using a t-test with a minimum cluster of 5 voxels, p <0.005 (T>2.5). The patient had a partial complex seizure, as noted by neurologist. The fMRI data showed positive BOLD responses (activation) in dysplastic areas, but showed the most significant activation outside the lesion, in areas compatible with secondary spread of the epileptic focus, probably caused by motor reaction also observed during the seizure. As a conclusion, we note that the technique of EEG-fMRI can detect the epileptogenic zone in patients with refractory epilepsy, but areas of dissemination of primary epileptogenic focus may show significant activation, introducing additional difficulties to the interpretation of the results

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Introdução: A variabilidade da frequência cardíaca (VFC) descreve o comportamento dos intervalos RR que está relacionado às ações do sistema nervoso autônomo (SNA) sobre o nódulo sinusal. Essa pode ser influenciada por diversos fatores dentre eles a obesidade, doença de etiologia multifatorial definida como um acúmulo excessivo de gordura corporal. Objetivo: Avaliar em jovens obesos com idade entre 18 e 23 anos o comportamento autonômico cardíaco, durante o repouso, por meio da análise linear e não linear dos índices da VFC bem como associá-lo a eventos de desconforto músculoesquelético influenciados ou não pela prática regular de exercício físico nessa população. Metodologia: Para a realização deste estudo foram analisados dados de 68 voluntários jovens, de ambos os sexos, distribuídos de forma não randomizada em dois grupos: o G1 constituído por 32 obesos, 20,21 ± 1,66 anos e o G2 por 36 não obesos, 20,8 ± 1,47 anos sendo considerado como critério de classificação dos voluntários o índice de massa corpórea (IMC). O protocolo experimental consistiu da captação da frequência cardíaca batimento a batimento, por meio de uma cinta de captação fixada no tórax do voluntário juntamente com um receptor de frequência cardíaca fixado no punho. Para esta captação o voluntário foi orientado a permanecer em repouso na posição de decúbito dorsal sobre um colchonete, durante 30 minutos, com a respiração espontânea. Além disso, foram aplicados dois questionários, ou seja: versão curta do International Physical Activity Questionaire (IPAQ) - Questionário Internacional de Atividade Física, a fim de classificar o nível de atividade física e o Questionário Nórdico, para detectar eventuais sintomas osteomusculares decorrentes das atividades de vida diária e/ou atividades física. Os índices da VFC analisados foram: análise linear... (Resumo completo, clicar acesso eletrônico abaixo)

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Cataract is the leading cause of blindness in dogs. It is defined as an opacity in the lens and is independent of resulting visual deficit. Although there are a growing number of studies related to drug therapy of cataract, the treatment is still considered exclusively surgical. Among the techniques used to remove cataract, phacoemulsification is the best performer. Anesthesia in intraocular surgery has several peculiarities, which are essential to successfully conduct phacoemulsification in dogs. In these patients, a safe and effective anesthesia requires the maintenance of intraocular pressure close to normal, preventing the activation of the oculo-cardiac reflex and complete immobilization of the eye. The appropriate conditions for such surgical procedures can be established through the use of drugs from different pharmacological groups for premedication, induction and maintenance of anesthesia, making a balanced anesthesia. This work was compiled from a careful review of the literature on anesthesia in cataract surgery. Considerations on the pre-medication, induction and maintenance of anesthesia are discussed, aiming to contribute to the phacoemulsification becomes more safe and suitable for the anesthesiologist and the surgeon as well as comfortable for dogs undergoing surgery

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It is imortant to be able to evaluate the cardiact size . In 1995, was proposed by Buchanan and Bücheler a new way to measure the dimensions of the cardiac silhouette. This study aims to gather several studies of the cardiac dimensions by VHS method in the right lateral recumbency of of different breeds of dogs in a single work, facilitating the assess to information. Deep chest breeds have a smaller mean VHS value than the barrel chest breeds, showing that there is a variation of the VHS values acoording to the thoracic conformation of each breed, which indicates that there is a need to recognize the specific VHS values according to the breed standard to not to interpret the cardiac measurement in a wrong way through not compatible reference values for the animal. There is the individual variation that should be taken into accont at the time of measurement. The VHS is a helper method to a radiographic evaluation of the heart, and the ultrasonography remains the gold standard for the evaluation of the cardiac chambers and other changes of the heart

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A tripanossomíase americana – Doença de Chagas – é uma parasitose típica de países tropicais e subdesenvolvidos. Devido a grande abrangência da doença, somada a dificuldade encontrada pelos pacientes para adquirir os medicamentos, Chung et al. (1996) sintetizaram o pró-fármaco hidroximetilnitrofural (NFOH). Esse derivado do nitrofural (NF), em estudos preliminares, apresentou resultados significativamente superiores aos observados com benznidazol e nitrofural, disponíveis para a terapia convencional. O presente estudo teve como objetivo a avaliação preliminar do potencial de hepatotoxicidade e cardiotoxicidade do NFOH quando administrado a coelhos albinos. O protocolo experimental se deu através da avaliação da atividade sérica dos biomarcadores hepáticos AST, ALT, GGT e bilirrubina, e do cardíaco CK-MB. Os animais foram divididos em três grupos (n=5), que receberam NFOH, NF e o veículo DMSO duas vezes ao dia, durante 24 dias. Para realização das análises foram coletadas amostras de sangue a cada seis dias. Os testes foram realizados através de kits bioquímicos para diagnóstico (Labtest®). Os níveis de AST e ALT dos grupos expostos aos fármacos apresentaram significativa diminuição com relação ao grupo controle, a bilirrubina não apresentou alterações significativas, e a atividade sérica da GGT apresentou-se elevada tanto nos grupos NFOH e NF quanto no grupo controle. Foi observada alta mortalidade entre os animais expostos ao NF e os valores de CK-MB foram significativamente superiores aos valores de referência descritos em literatura, sugerindo dano cardíaco. Tendo como base tais resultados, concluímos que o pró-fármaco não originou prejuízos relacionados ao tecido hepático, porém com relação à cardiotoxicidade há necessidade de estudos posteriores.

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Introduction: The triangular index and the Poincaré plot (or Lorenz plot) are the best known indexes obtained from geometric methods. The triangular index (TINN, RRtri) represent the global variability of the subject and SD1, which reflects the parasympathetic component, SD2, index of global variability and its relationship (SD1/SD2) are obtained from the Poincaré plot. Despite the literature showing changes in the cardiovascular system during and after the resistance exercise (RE), aspects related to autonomic modulation of heart against these conditions have not been explored yet, so it is important to evaluate this behavior. Objectives: Analyze the acute effects of RE on the cardiac autonomic modulation during recovery (REC) through analysis of geometric indices of heart rate variability (HRV), applied with different intensities and muscle groups in healthy and active young. Methods: Were evaluated 24 young, 22.25 ± 2.4 years and 24.47 ± 3.08 kg/m2, underwent an experimental protocol of five stages, in the first stage was conducted a test of one maximum repetition (1RM) in upper limbs (UL) and lower limb (LL), and the following steps were initiated interventions to 40 (E) and 80% (F) of 1RM. Considered for HRV analysis the periods: baseline and immediately after exercise, both in supine... (Complete abstract click electronic access below)

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Infective endocarditis is a process in which an infection attacks the heart endothelial surface, and is commonly caused by bacterial colonization, which is called bacterial endocarditis. It is a condition rarely found in dogs and cats, and is more prevalent in male dogs of large size. It mainly affects the left side of the heart, affecting the mitral and aortic valves with greater frequency. The circulation of the bacterium in the bloodstream is what gives rise endocarditis, and is caused by any non-aseptic process that serves as a gateway for bacterium in the body, as from a skin lesion, even as an invasive procedure, such as, catheterization and surgery. The ante-mortem diagnosis is difficult because the clinical signs of endocarditis are varied and common to other diseases, summing up the signs of infection (fever, lethargy, weight loss), and presence of heart murmur and may show signs of congestive heart failure. Thus, the diagnosis is most often through autopsy. To arrive at a diagnosis should be used, besides the history and physical examination, some laboratory tests, especially blood cultures and echocardiography. Treatment is accomplished through the use of antibiotics for long period of time, it is very important to follow the results of susceptibility after its outcome is revealed. The prognosis for bacterial endocarditis ranges from guarded to poor, and can be assessed mainly by the echocardiography. There are few studies in veterinary about the bacterial endocarditis, and the majority is case reports

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The aim of this study was to analyze the influence of prior exercise on different intensity distribution strategies (pacing). The study included five male individuals, apparently healthy, aged between 18 and 25 years, and without regular practice of physical activities. The subjects were tested on different days following the protocols on a cycle ergometer: 1) a progressive ramp test, 2) three constant load tests in the intensities of 85%, 90% and 95% IVO2max to exhaustion, and 3) six tests with and without holding a prior exercise intensity of 70%  with different strategies for Even-intensity pace, ES (401 ± 70 W), which consists of an exercise at a pace and / or constant intensity from beginning to end; where intensity is initially increased to 10% less than the ES progressively increase to reach 10% above the intensity of ES, and; Fast-start; FS, where there is a reversal in the way of distributing intensity, ie the initial intensity is 10% higher than the value of ES decreased progressively to 10% below that ES. All these tests were performed in random order. The tlim with previous exercise was significantly shorter than without previous exercise at FS condition (p < 0.05). The VO2final obtained at ES condition was similar with (3243 ± 599 ml.min-1) and without (3252 ± 384 ml.min-1) previous aerobic exercise (p > 0.05). However, the VO2final obtained at FS condition was higher with (3291 ± 218 ml.min-1) than without (3097 ± 207 ml.min-1) previous aerobic exercise (p < 0.05). The heart rate was higher at ES condition with than without previous aerobic exercise (p < 0.05). There was no significant difference in this variable for FS condition with and without previous aerobic exercise (p > 0.05). It can be concluded that the results the previous exercise (70%) achieved lasting 6 minutes followed by 6 minutes of recovery appears to influence / commit ting the conditions during the pacing for this population

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Pós-graduação em Medicina Veterinária - FCAV

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This paper considers a study of the anatomical features of the cardiac system and a three-dimensional model of the different tunics that comprise the heart wall, for processing and quality control of radiological images. The structures are built by the layer overlapping method, where a layer can be understood as a slice of the three-dimensional object. The pericardium, myocardium and endocardium were represented with three-dimensional cylinders and hexagons. The spatial arrangement of the cardiac system is determined by an background image of a real model, which values are defined according to the shape of the region and on the anatomical patients characteristics. The results are significant, considering the anatomical structures details, as well as the representation of the thicknesses of the regions of the heart wall. The validation of the anatomical model was accomplished through comparisons with dimensions obtained from a real model and allows verifying that the model is appropriate. The degree of representation will allow the verification of the influence of radiological parameters, morphometric peculiarities and stage of the diseases on the quality of the images, as well as on the performance of the Computer-Aided Diagnosis (CAD).

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Pós-graduação em Fisioterapia - FCT

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Introduction: Aortic insufficiency (AoI), a volume overload, is characterized by the diastolic reflux of blood from the regurgitating aorta to the left ventricle. This effect results from malfunctioning aortic cusps. The main cause of AoI in developing countries is rheumatic fever, including Brazil, and valvar degeneration in developed countries. There is a strong association between cardiovascular diseases and depression. Selective serotonin reuptake inhibitors (SSRI) are one of the most prescribed antidepressants in the world. Previous studies of our laboratory showed that the utilization of a SSRI, paroxetine, improved cardiac function in rats with sub-chronic AoI and reduced the daily ingestion of hypertonic sodium (NaCl 0,3M). Cardiovascular diseases can determine behavior changes like increase of anxiety, and it is yet unknown if AoI would determine anxiety or anhedonia, incapacity of obtaining pleasure through physical or sensorial experiences. A possible target for SSRI action could be a change in the expression of enzyme isoforms that collaborate in the contractile function of the heart muscle, like the heavy chains of myosine, the sarcoplasmatic reticulum Ca2+/ATPase (SERCA) and its regulator protein, phospholamban (PLB). Objectives: Evaluation of behavior parameters for anxiety and anhedonia state and genic expression of a-myosine, b-myosine, SERCA2a and PLB in the heart tissue of rats with subchronic AoI that received treatment with an SSRI (paroxetine) for 4 weeks. Methods: Surgery to induce AoI was performed on male Wistar rats, anxiety was evaluated by the elevated plus-maze (EPM) and state of anhedonia was tested by ingestion of 2% sucrose solution. After euthanasia the heart tissue was collected and total RNA was extracted to be analyzed by the RT-qPCR method. Results: Heart fractional shortening was preserved in rats with AoI that were treated compared to rats with AoI that were not treated. There was no statistically ...