252 resultados para compromise
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Pós-graduação em Agronomia (Energia na Agricultura) - FCA
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Pós-graduação em Anestesiologia - FMB
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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In a previous research, it was observed that are symbolic exchanges established between the persons and the environment they live in that allow them to interact with others, leading them to reorganize their internal cognitive structures, reaching more elaborated stages. In the case of a person with deafness, the possibility of exchange can be compromised and knowledge about the construction of the temporal notion seems to be essential to enable a path of explanation about the difficulties they have regarding their cognitive development. Thus, based on the theory of Jean Piaget, the study intended to understand how the temporal notion constitutes as possible subject to the process of building the real, and examine, through empirical evaluation, if the difficulty in establishing symbolic exchanges caused by deafness would compromise the development of this notion. For this purpose, bibliographical research and empirical research were made, by the comparative evaluating between the performance of deaf and hearing subjects in relation to the construction of temporal notion. Two groups of subjects aged between 10 and 12 years were composed: one with three deaf subjects and another with 3 listeners. The assessment and analysis of the data were based on an experiment created by Piaget and his staff. The results showed that the listeners present responses from operative level, compatible with the age range in which they found themselves. In contrast, the deaf subjects showed responses of transition level, which indicates a situation of cognitive delay. We conclude that the potential compromise linguistic presented by deaf people, can hinder the activity representative causing delay in construction of temporal notion and consequently the development of thought. We conclude that the possible linguistic committal presented by deaf people can hinder the representative activity, causing delay in construction of temporal notion and consequently in the development of thought. In this sense, it seems that the Sign Language constitutes an important tool for deaf people because it allows symbolic exchanges that favor the cognitive development.
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Pós-graduação em Agronomia (Entomologia Agrícola) - FCAV
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Pós-graduação em Química - IQ
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Type 2 diabetes and obesity are increasing worldwide and linked to periodontitis, a chronic disease which is characterized by the irreversible destruction of the tooth-supporting tissues, that is, periodontium. The mechanisms underlying the association of diabetes mellitus and obesity with periodontal destruction and compromised periodontal healing are not well understood, but decreased plasma levels of adiponectin, as found in diabetic and obese individuals, might be a critical mechanistic link. The aim of this in vitro study was to examine the effects of adiponectin on periodontal ligament (PDL) cells under normal and regenerative conditions, and to study the regulation of adiponectin and its receptors in these cells. Adiponectin stimulated significantly the expression of growth factors and extracellular matrix, proliferation, and in vitro wound healing, reduced significantly the constitutive tumor necrosis factor-alpha expression, and caused a significant upregulation of its own expression. The beneficial actions of enamel matrix derivative on a number of PDL cell functions critical for periodontal regeneration were partially enhanced by adiponectin. The periodontopathogen Porphyromonas gingivalis inhibited the adiponectin expression and stimulated the expression of its receptors. In conclusion, reduced levels of adiponectin, as found in type 2 diabetes and obesity, may compromise periodontal health and healing.
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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The experiment was conducted to evaluate the intake, the digestibility and the performance of lambs fed with diets containing 0; 12,5 and 25% of mulberry hay in substitution of the concentrate. It was used a total of 24 lambs Ile de France breed, non castrated, average age 60 days and and 15 kg of body weight, confined, distributed in a completely randomized design. Voluntary intake of nutrients was not altered (P>0.05) by different percentages of mulberry hay inclusion in the concentrate, except ether extract which decreased linear (P<0.01). The digestibility of nutrients, days on feeding, daily weight gain and the feed conversion, were also not affected (P>0.05). The partial substitution of the concentrate, based on soybean meal and corn grain, by mulberry hay up to 25% does not compromise the intake, the digestibility of nutrients and the performance of diet of feedlot lambs.
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)