Correlação das características ultrassonográficas com perfil imunoistoquímico dos tumores mamários malignos

Pós-graduação em Ginecologia, Obstetrícia e Mastologia - FMB

Avaliação da utilização de subprodutos de Coffea arabica L. para fins cosméticos

Dentre as várias espécies de café, Coffea arabica L. destaca-se pela sua ampla importância comercial relacionada ao consumo da bebida e à produção de óleo. O grão de café possui grande quantidade de compostos fenólicos bioativos - destacando-se os com atividade antioxidante e fotoprotetora - e após a extração do óleo há sobra de grande quantidade de subprodutos, denominado torta. O objetivo desse trabalho é produzir um extrato a partir da torta de café selecionando o melhor solvente extrator, avaliando o teor de compostos fenólicos e o potencial antioxidante, para o emprego como ativo cosmético em formulações desenvolvidas, com análise in vitro para quantificação do Fator de Proteção Solar (FPS) dessas. Os extratos foram previamente produzidos por sonicação utilizando solventes de diferentes polaridades, e o extrato escolhido foi produzido em maior escala por maceração e realizado também extração exaustiva com o solvente escolhido (extrato etanólico 70%, v/v). Na determinação do teor de fenólicos totais foi utilizado o método com o reagente Folin-Ciocalteu. Foi avaliado também o rendimento (m/m) dos extratos e atividade antioxidante pelo método do radical DPPH. O extrato apresentou boa atividade antioxidante e alto teor de compostos fenólicos em comparação com outras plantas consideradas referências nessas propriedades. Para o preparo das formulações foram utilizados matérias primas aprovadas pela ANVISA, e as quantidades dos filtros solares químicos empregados para obtenção de Fator de Proteção Solar (FPS) teórico próximo de 30, utilizou-se como ferramenta o BASF - Sunscreen Simulator. As formulas desenvolvidas e preparadas foram analisadas com o equipamento Optometrics SPF 290S, capaz de fazer a determinação do FPS por análise in vitro. A preparação selecionada foi a que apresentou FPS adequado pela análise in vitro e sensorial mais leve, visto ...

Considerações e avaliações das solicitações em estruturas de edificações de paredes de concreto pré-moldado utilizando o modelo de pórtico tridimensional: estudo de caso

The present study is in reference to precast concrete (panels) walls as the main structural system. The diversification of the structural systems is a reality due to specific characteristics', as a result there is a lack of study and analysis. Some systems are already established in their applications, for instance: conventional reinforced concrete, structural masonry, metal structures, and wood structure. Apart from this precast concrete elements has had a growth in building sites in Brazil, therefore professionals should be more aware. Affordable house funding initiatives to address the housing shortage has been recurrent throughout the country, additionally precast concrete walls has been an alternative that meets the three basic concepts of engineering, which are: the technique, economy, and security. The objective of this study is to gather concepts from the literature and TOMO (2012) about precast concrete walls and make a didactic synthesis of how they are viewed. The modeling structure method of the system was performed following the concept of assigning bars, using the computer program of calculations SAP2000. Initially will be presented a theoretical part, furthermore a case study to illustrate the sizing of the walls using EXCEL tables programmed with calculation routine. The results will be presented in calculated efforts by the program for further analysis. Finally, will be highlighted important items of modeling and interpretation of the results

Estudos sobre a aplicação do pentacloreto de nióbio na síntese de derivados de 4-aril-3,4-di- hidrocumarinas

Coumarin is a natural active compound that can be found in many plants. The coumarins have many properties such as bronchodilator, anti-inflammatory, antioxidant, anticoagulant, antibiotics, immunomodulatory, antimicrobial and antiviral, thus, they are widely used in medical applications. More recently the coumarin derivatives have attracted the interest of many research groups in the field of new materials, for example the possibility of their use as sensitizers in dye-sensitized solar cells (DSSC) and lasers. The MCRs are defined as a process in which three or more reactants are combined in the same reaction pot, resulting in products with good structural complexity a single step, in addition to economy of atoms and selectivity and is a very important feature in modern synthetic methodology. In this work we investigated the use of niobium pentachloride as catalyst of the multicomponent reactions between phenolic derivatives, various aromatic aldehydes and β-diester derivatives in the synthesis of 4-aryl-3,4-dihydrocoumarin derivatives. The reactions were carried out at room temperature, under inert atmosphere (N2), using dichloromethane anhydrous (CH2 Cl2) as solvent, with a reaction time of most 120 hours. The products were isolated by column chromatography on silica gel and submitted to spectrometric and spectroscopic analysis. The results show that NbCl5 is an excellent agent for promoting the synthesis of 4-aryl-3,4-dihydrocoumarin derivatives through multicomponent reactions, obtaining yields varying from 45 to 95%

Viabilidade técnica e econômica do uso da energia solar térmica em condomínios horizontais com habitações populares

Pós-graduação em Engenharia Mecânica - FEG

Estudo da viabilidade de implantação de plantas para conversão de energia térmica do oceano (OTEC) no Brasil

Pós-graduação em Engenharia Mecânica - FEIS

Estudo dos processos de geração e transferência de cargas em corantes cianinas

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Utilização de procedimentos multivariados no consumo de água e energia elétrica em habitações sociais com sistema de aquecimento solar

Pós-graduação em Agronomia (Energia na Agricultura) - FCA

Revisão sistemática: Eficácia da quimioterapia e associações no tratamento do carcinoma espinocelular em gatos

O carcinoma espinocelular é uma das quatro neoplasias malignas que mais acomete gatos, principalmente os de pele clara e que residem em países tropicais onde a incidência de raios solares é intensa. O tratamento cirúrgico é o mais indicado, mas nem sempre é possível de ser realizado seja pelo estágio avançado do tumor, pela sua localização ou por opção do proprietário que não quer ver seu animal mutilado. O objetivo desta revisão sistemática foi verificar a eficácia da quimioterapia com ou sem associações terapêuticas para o tratamento do carcinoma espinocelular superficial, multicêntrico e de cabeça e pescoço em gatos. Os melhores resultados para o tratamento do carcinoma espinocelular superficial foram observados com a aplicação intralesional do quimioterápico associado à radioterapia ou à eletroterapia, para o tipo multicêntrico faltam trabalhos sobre o assunto e o único encontrado não apresentou resultados satisfatórios. No caso do carcinoma espinocelular de cabeça e pescoço que alberga o pior prognóstico, a terapia multimodal com associação de quimioterapia, radioterapia e excisão cirúrgica demonstrou ser eficiente. Mais estudos sobre o assunto devem ser realizados utilizando um número maior de animais e com um tempo de seguimento mais longo

Monitoramento das irregularidades ionosféricas e cintilação dos sinais GNSS: em tempo real e pós-processado

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Produção de chapas de partículas com resíduos de madeira Cordia goeldiana

The aim of this research consisted in the use of wastes from tropical wood (Cordia goeldiana) with low density and the polyurethane resin (mono and bicomponent) castor oil based in the manufacture of particleboards, generating subsidies as application in rural and civil construction, as well in the furniture industry. The particleboards were manufactured with 15% of polyurethane resin content (one part of pre-polymer and one part of polyol), compaction pressure of 4MPa, pressing temperature of 90 degrees C and press time of 7 minutes. The physical and mechanical properties investigated were density, moisture content, strength modulus in bending and internal bond, both obtained according to the recommendations of the Brazilian standard ABNT NBR 14810:2002. The mean values obtained for these properties were systematically superior to the Brazilian standard requirement. This point showed that it is possible the use of Cordia goeldiana wastes in the particleboard production. We confirmed the hypothesis of a significant linear relation between density and the internal bond of the panels, allowing the estimation of the internal bond of particleboards.

Utilização de alvos codificados do tipo ARUCO na automação do processo de calibração de câmaras

This paper presents a proposal for the automation of the camera calibration process, locating and measuring image points in coded targets with sub-pixel precision. This automatic technique helps minimize localization errors, regardless of camera orientation and image scale. To develop this technique, several types of coded targets were analyzed and the ARUCO type was chosen due to its simplicity, ability to represent up to 1024 different targets and availability of source code implemented with the OpenCV library. ARUCO targets were generated and two calibration sheets were assembled to be used for the acquisition of images for camera calibration. The developed software can locate targets in the acquired images and it automatically extracts the coordinates of the four corners with sub-pixel accuracy. Experiments were conducted with real data showing that the targets are correctly identified unless excessive noise or fragmentation occurs mainly in the outer target square. The results with the calibration of a low cost camera showed that the process works and that the measurement accuracy of the corners achieves sub-pixel precision.

Sonochemical effects on ZnO particles

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Análise de projetos arquitetônicos modernistas com interferências visuais no Brasil

Modernism was a movement that began in the 1920s through the critical activities of Oswald de Andrade, Menotti del Picchia, Mário de Andrade and others who warned of the valuation of national roots. Thus exposed their ideas renewing groups of artists who begin to unite around a new aesthetic proposal. Modern architecture in Brazil had its origins in European avant-garde in the early twentieth century as well, represented by architect Antonio Moya. In 1923 arrives in São Paulo Warchavchik the architect, who always insisted on the same character "modern" time and "Brazil" in its architecture. Years following: architects claim in full, influencing young architects. This research aims to analyze the projects executed by some architects that have reshaped or rewrote the architecture in Brazil with modernism and artistic / visual interference with paneled walls and details entered in these buildings.

Análise dos riscos físicos e ergonômicos em roçadora transversal motorizada

According to Statistical Yearbook of Social Security (2011), the number of accidents at work recorded in the agricultural sector is quite high, in the year 2010 there are records of thirty-four thousand nine hundred and ninetysix accidents, and in the year of 2011 there were thirty-one thousand and ninety-six accidents in the industry. Among so many diseases and accidents at work hearing loss is one of them. According to the Pan American Health Organization (2011) the Occupational hearing loss is then jury to the worker's health, often in the workplace. Mechanical vibrations are also present in many human activities exposing employees to an extremely aggressive agent. The combined action of these two factors can cause damage to the health of the worker, in this way, noise and vibration are the two major occupational agents present in the brush cutter operator activity. In the case there is another risk factor, the open work, which exposes the employee to the Sun’s rays and the high temperature indices. Studies have shown that: noise exceeds 115 dB (A) vibration 4.0 m/s2 and thermal stress of 29.9 o C. Ergonomic evaluations also demonstrated that the activity cause injury to workers.