Clinical, cytologic, and histologic features of a mammary micropapillary carcinoma in a dog

Mammary invasive micropapillary carcinoma is a rare variant of mammary carcinoma that was recently recognized in dogs. The cytologic features and biologic behavior of such neoplasms in dogs have not yet been widely discussed in the veterinary literature. We report the clinical, cytologic, and histologic features of a canine micropapillary carcinoma in a 13-year-old female mongrel dog. The mammary region presented with extreme local pain, severe edema and erythema, and multifocal epidermal ulceration, which is typical for an inflammatory mammary carcinoma. Fine-needle aspirates were highly cellular and consisted of individual cells and papillary cell clusters with characteristics of malignant epithelial cells. Histologic examination revealed neoplastic cells arranged in small papillae without fibrovascular cores, sometimes inside clear lymphatic spaces, indicating lymphovascular invasion. Regional lymph node evaluation revealed metastatic cells. Due to deteriorating clinical condition the dog was euthanatized 5 months after mastectomy. At necropsy, metastatic neoplastic mammary cells were found in popliteal and mediastinal lymph nodes, the right femoral biceps muscle, liver, heart, lungs, and urinary bladder. © 2013 American Society for Veterinary Clinical Pathology.

Effect of final irrigation protocols on microhardness and erosion of root canal dentin

The aim of this study was to evaluate the effect of final irrigation protocols (17% EDTA, BioPure MTAD, SmearClear, and QMiX) on microhardness and erosion of root canal dentin. Fifty roots were sectioned transversely at the cement-enamel junction and each root was sectioned horizontally into 4-mm-thick slices. The samples were divided into five groups (n=10) according to the final irrigation protocol: G1: distilled water (control group); G2: 17% EDTA; G3: BioPure MTAD; G4: SmearClear; and G5: QMiX. The dentin microhardness was then measured with a load of 25 g for 10 s. Initially, the reference microhardness values were obtained for the samples without any etching. The same samples were then submitted to the final irrigation protocols. A new measure was realized and the difference between before and after the procedures was the dentin microhardness reduction. In sequence, the specimens were submitted to SEM analysis to verify the dentinal erosion. The Kruskal Wallis and Dunn tests (α=5%) were used to compare the results. The dentin microhardness decreased for all final irrigation protocols. There was no significant difference between groups 2, 3, 4, and 5 (P>0.05), but this groups presented significant dentin microhardness reduction than G1 (P<0.05). In G2, occurred the highest incidence of dentinal erosion (P<0.05). 17% EDTA, BioPure MTAD, SmearClear, and QMiX promoted significant dentin microhardness reduction. © 2013 Wiley Periodicals, Inc.

Clinical features of pure obsessive-compulsive disorder

Objective Psychiatric comorbidity is the rule in obsessive-compulsive disorder (OCD); however, very few studies have evaluated the clinical characteristics of patients with no co-occurring disorders (non-comorbid or pure OCD). The aim of this study was to estimate the prevalence of pure cases in a large multicenter sample of OCD patients and compare the sociodemographic and clinical characteristics of individuals with and without any lifetime axis I comorbidity. Method A cross-sectional study with 955 adult patients of the Brazilian Research Consortium on Obsessive-Compulsive Spectrum Disorders (C-TOC). Assessment instruments included the Yale-Brown Obsessive-Compulsive Scale, the Dimensional Yale-Brown Obsessive-Compulsive Scale, The USP-Sensory Phenomena Scale and the Brown Assessment of Beliefs Scale. Comorbidities were evaluated using the Structured Clinical Interview for DSM-IV Axis I Disorders. Bivariate analyses were followed by logistic regression. Results Only 74 patients (7.7%) presented pure OCD. Compared with those presenting at least one lifetime comorbidity (881, 92.3%), non-comorbid patients were more likely to be female and to be working, reported less traumatic experiences and presented lower scores in the Y-BOCS obsession subscale and in total DY-BOCS scores. All symptom dimensions except contamination-cleaning and hoarding were less severe in non-comorbid patients. They also presented less severe depression and anxiety, lower suicidality and less previous treatments. In the logistic regression, the following variables predicted pure OCD: sex, severity of depressive and anxious symptoms, previous suicidal thoughts and psychotherapy. Conclusions Pure OCD patients were the minority in this large sample and were characterized by female sex, less severe depressive and anxious symptoms, less suicidal thoughts and less use of psychotherapy as a treatment modality. The implications of these findings for clinical practice are discussed. © 2013 Elsevier Inc. All rights reserved.

Estudo do meio físico para o uso da terra na bacia do rio Sete de Setembro, médio Araguaia-MT

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Modelagem numérica da superfície como instrumento de avaliação de curvas de nível na preservação de manacial de água

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Geoecologia da paisagem na avaliação do uso dos recursos Hídricos da parte inicial da bacia do Ribeirão das Posses - SP

Pós-graduação em Agronomia (Irrigação e Drenagem) - FCA

Planejamento urbano sustentável: diretrizes de urbanização embasadas nas características geomorfológicas/pedológicas de vertentes

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Compartimentação do meio físico, evolução morfológica e aspectos morfotectônicos em São Thomé das Letras (MG)

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Propostas de recuperação de áreas peri-urbanas erodidas com base em parâmetros hidrológicos e geomorfológicos: Córrego Tucunzinho (São Pedro/SP)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

A evolução dos processos erosivos na Bacia do Ribeirão Alam Grei - SP: uma contribuição ao planejamento ambiental

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Zoneamento geoambiental da bacia hidrográfica da Represa Laranja Doce - Martinópolis (SP)

Pós-graduação em Geografia - IGCE

Planejamento Ambiental da Bacia Hidrográfica do Ribeirão Santo Antonio – Mirante do Paranapanema (SP)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

O Programa Estadual de Microbacias Hidrográficas em São Paulo: o caso do município de Assis/SP

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Vulnerabilidade Ambiental aos processos erosivos lineares nas áreas rurais do município de Presidente Prudente-SP

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Uso de geotecnologias na análise temporal dos impactos da urbanização na sub-bacia do Córrego Sem Nome em Ilha Solteira/SP

Pós-graduação em Engenharia Civil - FEIS