Influência do extrato de chá verde na remodelação cardíaca induzida por administração de doxorrubicina

Pós-graduação em Fisiopatologia em Clínica Médica - FMB

Participação das células Th1, Th2, Th17 e T regulatórias na doença de Jorge Lobo: análise do perfil de expressão gênica nas lesões

Pós-graduação em Doenças Tropicais - FMB

Impact of inulin and okara on Lactobacillus acidophilus La-5 and Bifidobacterium animalis Bb-12 viability in a fermented soy product and probiotic survival under in vitro simulated gastrointestinal conditions

The effect of inulin and/or okara flour on Lactobacillus acidophilus La-5 and Bifidobacterium animalis Bb-12 viability in a fermented soy product (FSP) and on probiotic survival under in vitro simulated gastrointestinal conditions were investigated throughout 28 days of storage at 4 °C. Employing a 22 design, four FSP trials were produced from soymilk fermented with ABT-4 culture (La-5, Bb-12, and Streptococcus thermophilus): FSP (control); FSP-I (with inulin, 3 g/100 mL of soymilk); FSP-O (with okara, 5 g/100 mL); FSP-IO (with inulin + okara, ratio 3:5 g/100 mL). Probiotic viabilities ranged from 8 to 9 log cfu/g during the 28 days of storage, and inulin and/or okara flour did not affect the viability of La-5 and Bb-12. Bb-12 resistance to the artificial gastrointestinal juices was higher than for La-5, since the Bb-12 and La-5 populations decreased approximately 0.6 log cfu/g and 3.8 log cfu/g, respectively, throughout storage period. Even though the protective effect of inulin and/or okara flour on probiotic microorganisms was not significant, when compared to a fresh culture, the FSP matrix improved Bb-12 survival on day 1 of storage and may be considered a good vehicle for Bb-12 and could play an important role in probiotic protection against gastrointestinal juices. © 2013 Elsevier Ltd.

Análise da suscetibilidade a corridas de massa aplicada a dutovias: estudo de caso na bacia do Ribeirão do Roque

This scientific research aimed at to analyse the susceptibility to debris flow of the watershed of Ribeirão do Roque (SP), focusing on the upstream areas of OSBRA pipeline. This is because, mass flow can cause damage to pipes, mainly due to conditioning hydro erosion of the land in the drainage crossings, including the undermining the banks of streams. Firstly, It was conducted a literature review, aiming to identify and understand the principal characteristics and conditions of debris flow. Secondly, the physical and anthropic factors and their respective weights of influence were selected and used to determine the mass flow susceptibility. It was selected the following physical factors: type and thickness of rocks, soil and unconsolidated materials; textural density; amplitude relief; relief slope; shaped valley; and shape of slopes. Such factors are present in the physiographic subdivision map of the study area. In addition, the anthropic attributes correspond to the classes contained in the land use map. Therefore, the physical and anthropic factors were integrated through the multi-criteria analysis in a GIS environment, generating a total susceptibility map of debris flow on the scale 1:50,000. The results showed that a significative part of the study area was classified as average susceptibility. However, it was identified areas with high susceptibility in the region in which the pipe cross the Ribeirão do Roque. Moreover, at which point the river presents a closed valley and a meander shape, without a fluvial plain that would be useful to attenuate the development of the process. Consequently, if a mass flow begins in any of these most susceptible regions located upstream of the pipe, the chances that the process develops by the river and causes the excavations of his bed are quite large. However, the pipelines cross these critical areas directly on the rock (diabase), which provides additional protection against possible ...

Micropartículas de goma gelana revestidas com filmes de amido resistente/pectina como estratégia para administração oral de insulina

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Ribavirin has an in vitro antiviral effect in rabies virus infected neuronal cells but fails to provide benefit in experimental rabies in mice

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Investigação da funcionalidade de haplótipos no gene Interleucina 4

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Caracterização por espectrometria de massas e investigação das atividades anti-inflamatória e gastroprotetora do extrato etanólico e diterpenos clerodânicos de folhas de Casearia sylvestris Swartz

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Análise de sistemas de proteção por redundância e bloqueio de energias contra acidentes em prensas e equipamentos rotativos

This monograph presents the main objective of analyzing the redundancy protection systems of protection for redundancy and block of energies against accident in presses and rotating equipment. After understanding two specific goals, on this case, show the systems of protection against accidents in rotating equipments, presses and similar; and discuss the vulnerabilities of current systems of protection against accidents in presses and similar, we will propose a system of autonomous redundancy of Programmable Logic Controller (PLC) operating simultaneously taking online in the event of failure of one of the two. The methodology was worked through a revision of a variety of bibliography, and interpretation of national and international standards as well as access to research on systems, practices used in industrial and companies supplying products and of companies and energy blockages solutions