199 resultados para Ciclagem térmica
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Hypothermia is a common phenomenon in the perioperative period, and it affects 60 to 90% of patients submitted to anesthetic-surgical procedures. In order to minimize its incidence, warming methods are used. Such methods can be passive, such as orthopedic cotton, sheets and blankets, or active, such as warm-air blankets and thermal mattresses. In this scenario, the present study aimed at comparing two warming methods used in the intraoperative period. Patients submitted to abdominal surgery in the specialties of gynecology and gastric surgery from August to September 2010 were included in the study. After randomization, they were divided into two groups: one using a thermal blanket (group I) and one using orthopedic cotton (group II). At last, 9 patients were included. The variables for each question were considered according to occurrence frequency. Comparison between groups was performed by Student’s t test. With the purpose to analyze whether there was an association, the chi-square test or Fisher’s Exact test was used. Whenever it was applicable for multiple comparisons, Tukey’s test was utilized; p values < 0.05 were considered to be statistically significant for analysis. The sample comprised 6 males and 3 females submitted to gynecological and gastric surgeries. Their mean age was 48 years for group I and 46.2 years for group II. A predominance of general anesthesia was observed. The time of permanence in the operating room ranged from 80 to 360 minutes. With regard to warming parenteral solutions, the procedure was performed on 5 patients, and infusion of warm solution into the abdominal cavity was performed on 50% of the sample. Concerning the warming method used, 5 patients used a thermal blanket. In view of the results presented, it was not possible to conclude which warming method should be used due to sample size
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Pós-graduação em Engenharia Mecânica - FEG
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Pós-graduação em Zootecnia - FCAV
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Pós-graduação em Ciência e Tecnologia de Materiais - FC
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Pós-graduação em Engenharia Mecânica - FEB
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O Ácido Kójico (AK) é uma substancia produzida por cepas de Aspergillus sp. Foi isolado pela primeira vez em 1907, através do estudo feito a partir do crescimento desse fungo em arroz cozido a vapor. É usado na cosmetologia como antioxidante e despigmentante para uso tópico. Atua como um potente antioxidante quelando íons de ferro e os íons de cobre presentes no seu sítio ativo da tirosinase impedindo a formação de melanina. O isononanoato de cetoestearila, utilizado na formulação, tem ampla utilização em cosméticos como cremes protetores de epiderme, cremes de maquiagens, cremes de proteção solar, loções e desodorantes por ser emoliente, não possuir cheiro e toque seco. Os sistemas nanoestruturados, como por exemplo, os sistemas líquidocristalinos aumentam a solubilidade dos princípios ativos incorporados ao sistema e aumentam a solubilidade dos princípios ativos incorporados ao sistema e aumentam a estabilidade e diminuem a toxidade, pois agem como reservatórios e dependendo da interação fármaco-sistema, altera a biodisponibilidade. O presente trabalho tem como objetivo desenvolver e caracterizar um sistema líquido cristalino constituído por água e isononanoato de cetoestearila (óleo), e estabilizado com o tensoativo álcool cetílico etoxilado e propoxilado contendo ácido kójico avaliando sua estabilidade através de estudos de termoanálises
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The albendazole and mebendazole drugs are benzimidazole derivatives and belong to the anthelmintic class. These drugs are particularly recommended for the treatment against worms present in the gastrointestinal tract of animals and humans, by acting directly on the worm metabolism. The need for thermally study drugs is related to all the parameters that these analyzes include: presence or absence of polymorphs, possible changes in the crystallinity of the drugs, as well as the quality control during the manufacturing process thereof. In this study the thermal behavior of anthelmintic albendazole and commercial mebendazole and its recrystallisation in organic solvents, such as acetic acid and formic acid in dimethylformamide to mebendazole, and albendazole were studied using TG-DSC techniques, TG-FTIR, FTIR and XRD. TG-DSC techniques were used so it could collect information about the thermal stability of the compounds steps for thermal decomposition process and also prove its melting temperature. For recrystallization of drugs in organic solvents, the TG-DSC curves were analyzed to compare and determine that the occurrence of polymorphs. The coupled TG-FTIR technique allowed the analysis of volatile products which were released during the thermal decomposition of the commercial mebendazole. The absorption spectroscopy in the infrared region was performed to mebendazole, and albendazole in order to show the difference in functional groups of both, comparing the spectra with commercial drugs and see if there was recrystallized changes in the absorption band where the drug was recrystallized or when heated. The diffraction technique by powder X-ray method was used for comparison of the crystal structures of commercial drugs and recrystallization in organic solvents to identify changes in crystallinity both, which might suggest the formation of polymorphs
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Pós-graduação em Engenharia Mecânica - FEG
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Pós-graduação em Engenharia Mecânica - FEIS
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Pós-graduação em Química - IQ
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This study evaluated the fatigue limit (FL) by the staircase method and the effect of mechanical cycling on the flexural strength (FS) of Duceragold feldspathic porcelain. Specimens (25 x 5 x 2 mm) were made according to manufacturer’s directions and submitted to three-point flexural strength test (n = 10). To determine FL (n = 30; 10,000 cycles; 2 Hz), an initial loading of 60% of the FS and an incremental loading (step) of 3% of the FS were used. Data were analyzed by Anova and Tukey´s test (p < 0.05). Although the proposed cycles have not reduced FS significantly, fractography analysis showed striation, characteristic signs of mechanical fatigue.
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
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Pós-graduação em Medicina Veterinária - FCAV
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)