A new species of Amerotyphlops from Northeastern Brazil, with comments on distribution of related species

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Study of lipid metabolism-related genes as candidate genes of sexual precocity in Nellore cattle

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Production, composition and processing of milk from ewes fed soybean seeds

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Cissus quadrangularis Linn exerts dose-dependent biphasic effects: osteogenic and anti-proliferative, through modulating ROS, cell cycle and Runx2 gene expression in primary rat osteoblasts

Objectives: This report highlights phytoconstituents present in Cissus quadrangularis (CQ) extract and examines biphasic (proliferative and anti-proliferative) effects of its extract on bone cell proliferation, differentiation, mineralization, ROS generation, cell cycle progression and Runx2 gene expression in primary rat osteoblasts. Materials and methods: Phytoconstituents were identified using gas chromatography-mass spectroscopy (GC-MS). Osteoblasts were exposed to different concentrations (10-100g/ml) of CQ extract and cell proliferation and cell differentiation were investigated at different periods of time. Subsequently, intracellular ROS intensity, apoptosis and matrix mineralization of osteoblasts were evaluated. We performed flow cytometry for DNA content and real-time PCR for Runx2 gene expression analysis.Results: CQ extract's approximately 40 bioactive compounds of fatty acids, hydrocarbons, vitamins and steroidal derivatives were identified. Osteoblasts exposed to varying concentrations of extract exhibited biphasic variation in cell proliferation and differentiation as a function of dose and time. Moreover, lower concentrations (10-50g/ml) of extract slightly reduced ROS intensity, although they enhanced matrix mineralization, DNA content in S phase of the cell cycle, and levels of Runx2 expression. However, higher concentrations (75-100g/ml) considerably induced the ROS intensity and nuclear condensation in osteoblasts, while it reduced mineralization level, proportion of cells in S phase and Runx2 level of the osteogenic gene.Conclusions: These findings suggest that CQ extract revealed concentration-dependent biphasic effects, which would contribute notably to future assessment of pre-clinical efficacy and safety studies.

Genetic characterization of Toxoplasma gondii isolates from eared doves (Zenaida auriculata) in Brazil

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Prevalência, distribuição espacial e fatores de risco para cisticercose bovina no estado de São Paulo

This study aimed to determine the prevalence and geographical distribution as well as the factors and areas of risk associated with bovine cysticercosis in the State of Sao Paulo. 34.443 cattle, males and females with ages from 18 to 60 months were inspected. The animals were from 97 cities in the state of Sao Paulo and identified and slaughtered in the period October 2010 to August 2011, in a refrigerator located in Ipua - SP, under the supervision of SIF 1387. The state of Sao Paulo was divided into regional centers, and the data of the municipalities belonging to its core, were grouped according to the Department of Agriculture and Food Supply of Sao Paulo, totaling 13 cores studied. Based on these results, we can conclude that of the 97 cities analyzed, cattle were found positive for the disease in 86. The average prevalence of bovine cysticercosis in the state of Sao Paulo was 4.80 %, while the core inflation Franca and Barretos were the ones with the highest number of cases illness during the analysis period. Moreover, the largest number of cases in these core coincided with the lowest human development index covering education, with the largest acreage of coffee (core Franca) and also as the largest area of cane sugar grown (core Barretos) in these locations, which in turn may indicate that the presence of labor, temporary labor in rural areas, combined with socioeconomic/cultural factors might contribute to the spread and establishment of bovine cysticercosis in these areas.

Cancelamento de cirurgias eletivas: dos motivos à compreensão do itinerário Agendamento-Centro Cirúrgico

Pós-graduação em Enfermagem - FMB

Adição de plasma bovino em salmouras para injeção de coxão duro bovino (m. Biceps femoris) e seus efeitos no pH e na carga microbiana de bifes cozidos embalados à vácuo e mantidos sob refrigeração

The physical (pH) and microbiological (psychotrofi c microorganisms and lactic bacteria) characteristics of beef outside round (m. Biceps femoris) injected (15%) with brines free of polyphosphates containing and sodium lactate or sodium lactate and sodium diacetate and liquid bovine plasma (PLL and PLO) or dehydrated bovine plasma (PDL, PDO) were evaluated along with beef cuts injected with brines free from plasma, but containing polyphosphates and bacteriostatic agents (CL and CO) and non injected beef cuts (IN), comprising seven treatments of cooked and vacuum packaged beef steaks stored under refrigeration (6ºC) during 43 days. No differences in pH were detected among raw or cooked injected treatments, although IN showed lower pH value in raw beef cuts. The addition of liquid or dehydrated bovine plasma did not affect the microbial load after whole muscles pasteurization, but increased the bacterial counts in cooked beef steaks during refrigerated storage, comparing to treatments with no plasma addition (CL and CO). The storage temperature (6ºC), usually found during commercialization of meat increased the microorganisms growth rate affecting the microbiological quality, especially when plasma was added to the brine.

Development of an anti aging cream with AHA/BHA and sunscreens

The skin aging is a matter of discomfort verified in the population. Thus, every day, new products are launched on the market to offer different manners to prevent the premature aging of the skin. In this context, active substances, as alpha and beta hidroxyacids (AHA/BHA), beyond the sunscreens, are considered a way of prevention and amelioration of the effects caused in the skin due to the time. The aim of this study was to develop and evaluate a cosmetic cream containing AHA/BHA and sunscreen. It was studied in relation to its physical-chemical and microbiological characteristics. According to the results, the formulation developed present a shelf life of 758 days and the preservative system was effective. Considering the parameters evaluated, the cream probably would be commercially accepted.

Development of an anti-aging cream with AHA/BHA and sunscreens

The skin aging is a matter of discomfort verified in the population. Thus, every day, new products are launched on the market to offer different manners to prevent the premature aging of the skin. In this context, active substances, as alpha and beta hidroxyacids (AHA/BHA), beyond the sunscreens, are considered a way of prevention and amelioration of the effects caused in the skin due to the time. The aim of this study was to develop and evaluate a cosmetic cream containing AHA/BHA and sunscreen. It was studied in relation to its physical-chemical and microbiological characteristics. According to the results, the formulation developed present a shelf life of 758 days and the preservative system was effective. Considering the parameters evaluated, the cream probably would be commercially accepted.

Dispositivo estratégico, resistência e relações de poder: um ensaio sobre a identidade do Centro de Educação Matemática (CEM) e seu papel na (E)educação (M)matemática brasileira

This paper presents some results of the investigation on the Mathematical Education Centre (CEM), a group of mathematics teachers’ educators in São Paulo, Brazil, acting mainly between 1984 and 1997. The essay, marked by an effort to constitute the identity of the CEM based on Foucault, assumes that the identity constitution process is not about what CEM is or was, but mainly about a set of possibilities of apprehending it from its historically contextualized strategies and initiatives. In this Foucauldian reading, which brings about concepts such as "strategic device", "resistance" and "power relations", the CEM constitution appears while it creates conditions for the constitution of Brazilian modern mathematical education.

Mona Lisa: sentidos múltiplos de um sorriso enigmático

This article reviews the history of the famous painting by Leonardo da Vinci, the Mona Lisa or Gioconda, sixteenth century, aiming to discuss about some of the multiple senses (or discourses) around its meaning, with the support of the French branch of the Discourse Analysis, especially based on concepts developed by D. Maingueneau. As it is characteristic of the work of art, the senses are open, which does not exclude the possibility of detachment, among which we accentuated the "Mona Lisa smile" as one of the main traits of the authorship by Leonardo Da Vinci and, simultaneously, a trait propitious to aphorisation. Thus, the work of art is releasing of the exclusive authorship of Da Vinci and it suscitates several rereadings, which help composing a discursive ethos around this consecrated painting and, at the same time, which make circulating distinct stereotypes.

Suppression of vibrations in a nonlinear half-car model using a magneto-rheological damper

The present work investigates the nonlinear response of a half-car model. The disturbances of the road are assumed to be sinusoidal. After constructing the bifurcation diagram, we use the 0-1 test to identify chaotic motions. The main objective of this study is to eliminate chaotic behavior of the chassis and reduce its vibrations. To accomplish this, a semi-active vehicle suspension control system, using magneto-rheological dampers, is proposed. The proposed semi-active control strategy consists of two nonlinear control laws: a feedforward control, and a feedback control. They are obtained by considering the SDRE (State Dependent Riccati Equation) control, where the control parameter is the voltage applied to the coils of the magneto-rheological dampers. Numerical results show that the proposed control method is effective in significantly reducing of the chassis vibration, increasing, therefore, passenger comfort.

Estudos experimentais e teórico-computacionais de novos complexos nanozeólitas-enzimas empregados na produção de biocombustíveis

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)