Construction of ethics in clinical research - Clinical trials registration

Scientific development that has been achieved through decades finds in clinical research a great possibility of translating findings to human health application. Evidence given by clinical trials allows everyone to have access to the best health services. However, the millionaire world of pharmaceutical industries has stained clinical research with doubt and improbability. Study results (fruits of controlled clinical trials) and scientific publications (selective, manipulated and with wrong conclusions) led to an inappropriate clinical practice, favoring the involved economic aspect. In 2005, the International Committee of Medical Journal Editors (ICMJE), supported by the World Association of Medical Editors, started demanding as a requisite for publication that all clinical trials be registered at the database ClinicalTrials.gov. In 2006, the World Health Organization (WHO) created the International Clinical Trial Registry Platform (ICTRP), which gathers several registry centers from all over the world, and required that all researchers and pharmaceutical industries register clinical trials. Such obligatory registration has progressed and will extend to all scientific journals indexed in all worldwide databases. Registration of clinical trials means another step of clinical research towards transparency, ethics and impartiality, resulting in real evidence to the forthcoming changes in clinical practice as well as in the health situation.

Committees for ethics in research involving human subjects

In Brazil since October 1996 there have been guidelines for research involving human subjects. Now human subjects know when their treatment is part of research. Deceit is no longer tolerated. But is not enough to say we offer an explanation to the potential subject and we offer a choice before he or she is confronted with an informed consent form. As in all professional activity, scientific investigation needs social controls. In Brazil, the ultimate responsibility of an investigation lies on the investigator, but in every institution where research is carried out there is a Committee for Ethics in Research. All Committees are subordinated to the National Commission of Ethics in Research, which is submitted to the Brazilian Institute of Health. During 2005 around 17,000 protocols involving 700,000 human subjects were revised by 475 Committees distributed all over the country. Approximately 7,000 people are now working in these Committees.

A Pilot Study Addressing the Impact of Religious Practice on Quality of Life of Breast Cancer Patients During Chemotherapy

The aim of this preliminary study was to investigate whether religious practice can modify quality of life (QoL) in BC patients during chemotherapy. QoL and religion practice questionnaire (RPQ) scores were evaluated in a sample of BC patients in different moments. Before chemotherapy initiation, women with lower physical and social functional scores displayed higher RPQ scores. On the other hand, low RPQ patients worsened some QoL scores over time. Body image acceptance was positively correlated with religious practice and specifically praying activity. This preliminary study suggests the importance of religion in coping with cancer chemotherapy. © 2011 Springer Science+Business Media, LLC.

Uma pesquisa sobre a opinião pública sobre incentivos financeiros para doação de óvulos no Brasil

Objective: The objective of this study was to assess the opinions of the Brazilian population about incentives for oocyte donation. Methods: A cross-sectional descriptive approach was used to consult the Brazilian public. The data collection involved the use of a structured questionnaire about legal and ethical issues surrounding oocyte donation. Individuals were randomly selected from the general population using different e-mail lists. Potential participants were contacted by e-mail and invited to participate in the study by completing an online web survey. Results: A total of 1,565 people completed the survey, including 1,284 women(82%) and 281 men(18%). Among the respondents, 1,309(83.6%) were university graduates, 1,033(66%) had a personal income ≥1,250 US dollars/month, 1,346(86%) considered themselves to be religious and 518 (33.1%) were health professionals. While many participants believed that women may donate their oocytes for altruistic reasons, the majority believed that a lack of oocyte donations is due to the prohibition of payments(64.3%) and that incentives would facilitate the decision to donate oocytes(84.7%). The majority of the participants(65.3%) agreed that a financial incentive(i.e., paying the donor) would be the most practical solution for increasing the number of oocyte donations. These results tended to be independent of gender, age, income, religion, education level and profession. Conclusion: While the Brazilian Federal Council of Medicine prohibits payments for oocyte donation, the majority of study participants had no objection to compensating oocyte donors. Moreover, most of the participants agreed that a financial incentive is the most practical solution to increasing the number of oocyte donations.

Arte e ética em The Bell de Iris Murdoch

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Reconhecimento ético em Hegel à luz do conceito de família

Pós-graduação em Filosofia - FFC

Digressões, transgressões, agressões: a Bíblia nos contos de Machado de Assis

Pós-graduação em Letras - IBILCE

O difícil enfrentamento do processo de morrer vivenciado pelo enfermeiro em unidade pediatríca

Pós-graduação em Enfermagem (mestrado profissional) - FMB

Poder e memória: o autoritarismo na igreja presbiteriana do Brasil no período da ditadura militar

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Library Classifications Criticism: Universality, Poststructuralism and Ethics

We study library classifications criticisms from a poststructuralist and pragmatist point of view that rejects the idea of universality in knowledge organization systems. From this perspective, we analize the seminal texts on library classifications criticisms and conclude that the seek of neutrality in some of these texts is not only an impossible goal but also a contradiction in the representation of different cultures. Therefore, we suggest the commitment with the goals and the recognition of bias in library classifications as an important device for achieving a transcultural ethics in knowledge organization and representation.

O lazer e a difusão da moral protestante

This study of qualitative nature, aimed to investigate the relations arising from experiences in the context of leisure in recreational activities offered in religious camps, with the spread of Protestant moral values .. The study was conducted with the union of literature and exploratory research. First, we sought to understand, through the specific literature, the Protestant society manifestation with its ethics and values, showing how leisure has been sought and appropriated by Protestants institutions. Subsequently, we developed an exploratory research, using as instrument for data collection a mixed questionnaire, applied to a purposeful sample comprised of participants of a religious camp of Protestant institution. Data were analyzed descriptively by Technical Analysis of Thematic Content and indicate that the activities offered at religious camp can diffuse Protestant values directly intentioned, in order to carry religious values so intrinsic to the task, and, indirectly meaning as a tool of evangelism, which are supporting the process of transmission of these values

A Poética do amor em O Romance da Rosa

We aim with this article to analyze the poetics of love in The Romance of the Rose. We think that Guillaume de Lorris’s conception of love is associated with the flourishing of the French courtly society of the XIII Century, and that Jean de Meun’s conception of love is a result of the decline of this same society. Behind the virtues offered by Guillaume to the medieval lover we find the notion of courtesy, of the art of living in society, the understanding of the poetry as a form of ethics, and the medieval poetic of desire – intimately associated with the religious mysticism appeared from the XI Century and with the troubadours’ poetry. Jean is more influenced by the Ovidian tradition of thinking about the causes and effects of love. In the first part of the poem, Guillaume idealizes the conquest of the Rose; in the second, Jean describes the cueillette of the Rose, which could be read as a rape, in an allegorical way. It is this tension between different conceptions of love in a same poem that makes possible a better comprehension of the ways people used to think and feel in the Middle Ages.