Avaliação da cinemática do complexo tóracoabdominal durante repouso e endurance muscular respiratória em obesos

Background: Obesity may affect the respiratory system, causing changes in respiratory function and in the pulmonary volumes and flows. Objectives: To evaluate the influence of obesity in the movement of thoracoabdominal complex at rest and during maximal voluntary ventilation (MVV), and the contribution between the different compartments of this complex and the volume changes of chest wall between obese and non-obese patients. Materials and Methods: We studied 16 patients divided into two groups: the obese group (n = 8) and group non-obese (n = 8). The two groups were homogeneous in terms of spirometric characteristics (FVC mean: 4.97 ± 0.6 L - 92.91 ± 10.17% predicted, and 4.52 ± 0.6 L - 93.59 ± 8.05%), age 25.6 ± 5.0 and 26.8 ± 4.9 years, in non-obese and obese respectively. BMI was 24.93 ± 3.0 and 39.18 ± 4.3 kg/m2 in the groups investigated. All subjects performed breathing calm and slow and maneuver MVV, during registration for optoelectronic plethysmography. Statistical analysis: we used the unpaired t test and Mann-Whitney. Results: Obese individuals had a lower percentage contribution of the rib cage abdominal (RCa) during breathing at rest and VVM. The variation of end expiratory (EELV) and end inspiratory (EILV) lung volumes were lower in obese subjects. It has been found asynchrony and higher distortion between compartments of thoracoabdominal complex in obese subjects when compared to non-obese. Conclusions: Central obesity impairs the ventilation lung, reducing to adaptation efforts and increasing the ventilatory work

Déficits de memória induzidos por baixas doses de reserpina em ratos: possível relação com prejuízos no processamento emocional na Doença de Parkinson

We have recently verified that the monoamine depleting drug reserpine at doses that do not modify motor function - impairs memory in a rodent model of aversive discrimination. In this study, the effects of reserpine (0.1-0.5 mg/kg) on the performance of rats in object recognition, spatial working memory (spontaneous alternation) and emotional memory (contextual freezing conditioning) tasks were investigated. While object recognition and spontaneous alternation behavior were not affected by reserpine treatment, contextual fear conditioning was impaired. Together with previous studies, these results suggest that mild monoamine depletion would preferentially induce deficits in tasks involved with emotional contexts. Possible relationships with cognitive and emotional processing deficits in Parkinson disease are discussed

Masculinidade a prova: um estudo de inspiração fenomenologico - hermeneutico sobre a infertilidade masculina

Culturally, childbearing is understood as a situation that subjects will experience at some point in their lives, especially people who are married or have a similar affectionate relationship. Thus, to realize the inability to meet such a fate seems to be a natural cultural trigger of suffering, frustration and feelings of inadequacy and helplessness. Specifically for men, infertility is closely related to loss of masculinity, virility. He fails in his role as a male. This study sought to understand the impact that infertility have on the existence of a man who receives such a diagnosis, both in self-image as in their marital, sexual and professional roles. This study sets up as a hermeneutic phenomenological research based on the ideas of the philosopher Martin Heidegger. Participants were seven heterosexual, married and infertile men. Two interviews were conducted. The analysis of the material included both the material of the narratives, as the affectation of the researcher when interacting with the participants and their narratives, through phenomenological-hermeneutic interpretation. The results corroborate the literature that states the difficulty of the men, immersed in a context that defines them as virile, powerful and invulnerable to worry about issues related to health and disease. The possibility of any condition that impairs the reproductive capacity exceeds the acceptable limits of daily life for these men, not being recognized as a model of masculinity present in the condition in which they recognize. This leads to questions about their masculinity, role in the marital relationship and their existence. Thus, to recognize themselves as infertile surpass a medical diagnosis and is associated with the construction of meaning for their existence from the approximation with the infertility condition, which helps in redirecting their choices, restoring the project to be self and allowing further recognition as men. In the marital relationship, doing what they can to ensure, theirs happiness. Through these actions, they remain playing the role of family provider, showing that they are able to protect their wives and taking in assisted reproduction or adoption of children viable alternatives to fulfill the desire to leave a legacy and give a child to their wives and to society. Another result observed, refers to the ontological condition of care that characterizes the human being. The ways in which men are treated socially demonstrates a type of care that focuses on the development of characteristics such as strength, virility and determination but does not allow them to cope with the suffering of emotionally difficult situations, such as the diagnosis of infertility. At the end, the study gives rise to reflections on the need to provide a 12 space for men and their expressions of suffering, as well as to recognize their ability to overcome the painful and difficult situations