Translocation of 99mTc labelled bacteria after intestinal ischemia and reperfusion

Ischemia and reperfusion of the small intestine disrupts gut barrier, causes bacterial translocation and activates inflammatory responses. An experimental study was planned to evaluate if 99mTc labelled Escherichia coli translocates to mesenteric lymph nodes, liver, spleen, lung and serum of rats submitted to mesenteric ischemia/reperfusion. Additionally, it was observed if the time of reperfusion influences the level of translocation. METHODS: Forty male Wistar rats underwent 45 minutes of gut ischemia by occlusion of the superior mesenteric artery. The translocation of labelled bacteria to different organs and portal serum was determined in rats reperfused for 30 minutes, 24 hours, sham(S) and controls(C), using radioactivity count and colony forming units/g (CFU). RESULTS: All the organs from rats observed for 24 hours after reperfusion had higher levels of radioactivity and positive cultures (CFU) than did the organs of rats reperfused for 30 minutes, C and S, except in the spleen (p<0,01). CONCLUSION: The results of this study indicated that intestinal ischemia/reperfusion led to bacterial translocation, mostly after 24 hours of reperfusion

Duas mãos e o sentimento do mundo: Hélio Vasconcelos

This thesis deals with the intellectual itinerary of the humanist, lawyer and educator RN Helio Vasconcelos in building a more cohesive society, just and egalitarian, less marked by inequality, by poverty, ignorance and lack of freedom of his people suffered and loved. It also shows, as after suffering the hardships caused by the political persecution and imprisonment, exile faced with dignity, developing an exemplary job of defending the rights of children and adolescents. For this, redo the way that intellectual humanist, simple man who never gave up their way of thinking, of viewing the world, to love and respect all that surrounds him, thinking globally and acting locally, always holding the defense Rights human. Helium shows how solidarity exercised intensely and as bothered with the real interests of the community to hold public office. It seeks to demonstrate the need for reformulation of Legal Education in order to stimulate the formation of a lawyer gifted humanist profile

Pedagogia da fraternidade ecológica e formação transdisciplinar para um ensino educativo

La séparation entre les deux cultures (Snow, 1995) a battu la compréhension du monde, a influencé l'éducation à tous les niveaux et a fragmenté les êtres humains dans leur façon de penser et de produire des connaissances. L'accumulation des connaissances héritées dès la naissance de la science moderne au XVIIe siècle, n'a pas été suffisantes pour relever les nouveaux défis du monde contemporain (Morin, 2000, 2001, 2002a). Maintenant c est le temps de chercher une nouvelle compréhension du monde et des nouveaux façon de comprendre et résoudre les événements et problèmes de l'âge moderne. La Pédagogie de la fraternité écologique "est défendue et construite à partir d'un point de référence cosmologique nouvelle, basée sur le grand récit de l'univers, et inspirés par la vie fraternelle, l'amour, la poésie et la sagesse de saint François d'Assise (Italie , sec. XII-XIII) et l'expérience des connaissances traditionnelles et la «logique du sensible» (Lévi-Strauss) de Francisco da Silva Lucas, un résident de la communauté de Areia Branca, sur les rives du lac Piató dans la ville de Assu, Rio Grande do Norte. Une épistémologie fondée sur le grand récit de l'Univers rachetera des relations fraternelles entre l'homme et la nature. À partir de ces références j ai elaboré une nouvelle formation pour les éducateurs, «formation interdisciplinaire pour enseigner de l'éducation», dans lequel je développe ce que j'appelle «Architecture transdisciplinaire de savoir pour la formation des enseignants, fondé sur les principes de la complexité et de la transdisciplinarité. Nous comprenons que notre rôle est plus large intégrant l'homme dans l'histoire de l'univers, car le bien de la terre et le bienêtre de la communauté humaine sur terre peut être le point que rejoindra l'enseignement de l'avenir

Um estudante cego no curso de licenciatura em musica da ufrn: questões de acessibilidade curricular e física

This work aims to discuss and analyze the process of school inclusion of a blind person in the Bachelor's Degree in Music, at the School of Music at the Federal University of Rio Grande do Norte, as well as reflect on the importance of establishing systems of support and to ensure university inclusive process of people with visual impairments. In pursuit to achieve these objectives, this research chose a qualitative methodological approach, the case study, using as procedures for data construction an interview, observation, analysis of documents and photographs. Joined the group of participants in this study, a blind student in the class of 2009.1of the EMUFRN Bachelor's Degree in Music, teachers from two disciplines complied by the student, two classmates, a monitor support in music theory, the course coordinator and school principal, and two other individuals who contributed to the inclusion process in actions not formalized institutionally. The results indicate UFRN proposed initiatives that contribute to inclusion of students with disabilities in this institution, the main one is the creation of the Standing Committee of Support for Students with Special Educational Needs (CAENE), a group that guides administrative sectors, teachers, principals, coordinators and students on the measures needed to enter and remain in quality education for all. Physical accessibility is still under construction at UFRN, and many access and sectors see it being adapted for students with physical or visual disabilities, and those with mobility impairments, have access to various parts of the university, however, as shown in this study, some points need to be reconsidered, as there are several places where the installation of tactile floor does not fully follow the guidelines proposed in the legislation. The proposals for access to the curriculum, mediated by EMUFRN, are actions that propose the inclusion of the blind student, as the existence of an educational monitor to help in the study of music theory, however, we need to rethink these proposals to not became actions of reactive intervention. Assuming a more proactive posture, the EMUFRN will be prepared to receive the diversity of students that expects. The study also points out that the blind student is part of a group of students that are practical musicians, who must work in events and evening shows, and who have little knowledge in music theory, leading, respectively, in low frequency classes and learning difficulties in certain curricular components, which may cause the closing of such components. In this case, the challenge of EMUFRN, considering the inclusive perspective, it is not specifically fit for the academic host a blind student, but to develop an accessibility project curriculum to consider effectively the diversity of all its students, taking into account mainly the economic and cultural conditions. This implies a process of resizing academic practices that be guided for collaborative and coordinated actions involving the various educational actors at EMUFRN and UFRN

Lagoa do Piató: a educação como uma obra de arte

A partir de una concepción de la educación como una obra de arte, la disertación revela los estudios realizados en una escuela de la comunidad de Areia Branca Piató, en la Laguna de Piató en Assú, Estado de Rio Grande do Norte. Como una forma de hacer dialogar conocimientos científicos y saberes tradicionales, la investigación establece el intercambio de saberes y afectos sobre todo por intermedio del intelectual de la tradición Francisco Lucas da Silva. Para construir un conocimiento pertinente (Edgar Morin), el que forma parte de un contexto, buscamos aquí la comprensión de una pedagogía viva e imaginativa. La disertación encontró en la Laguna un laboratorio vivo para pensar en una enseñanza educativa y para ejercer el pensamiento complejo. A partir de estudios e investigaciones anteriores, pude organizar lo que considero que se constituye como constelaciones de saberes que permiten dar continuidad a ese eje de investigación que empezó desde 1986 en el Grupo de Estudios de la Complejidad GRECOM. En la construcción de este trabajo, pude aprender valores que creo que son importantes para una educación compleja: la humildad delante de la vida; la abertura para diferentes lenguajes del mundo; el diálogo con la naturaleza; la apuesta en nuestras creencias; el sueño de resignificar a la realidad a partir del lazo entre la profundidad de nuestro ser y el mundo; el uso pleno de nuestras potencialidades imaginativas y creativas; y, finalmente, la vivencia intensa de los sentidos. Partiendo de ese aprendizaje, la investigación teórico‐práctica tuvo como elemento central el desarrollo de talleres sobre el tema del agua con alumnos de la enseñanza básicas de diversas series, y con la participación activa de dos profesoras de la comunidad de Areia Branca Piató. Fueron llevadas adelante experiencias que contemplaron una visión sistémica de la naturaleza, las fotografías, los atelieres, las clases de campo, el arte de educar, la narración de historias y sobre todo las enseñanzas del intelectual de la tradición Francisco Lucas da Silva

DERSU UZALA Hibridação Homem-Natureza

Esta disertación explora de qué forma las hibridaciones entre ser humano y ambientes naturales no urbanos contribuyen a configurar las estrategias de atención, de construcción de conocimiento y de interacción con el mundo del sujeto y cómo, recursivamente, las actitudes perceptivo-cognitivas y las maneras de acercarse a lo real, de imputar sentido a los fenómenos y de interactuar con el ambiente practicadas por el sujeto condicionan y contribuyen a definir las hibridaciones entre humanos y no humanos. Lo que guía esa exploración es el concepto de híbrido que, inspirándome en Bruno Latour (2008), concibo como una asociación entre elementos sin características inherentes, compenetrados, que se redefinen, recrean e reconfiguran recíprocamente. Utilizo como operadores cognitivos una narrativa literaria y una cinematográfica: el libro autobiográfico Dersu Uzala del escritor y explorador ruso Vladimir Klavdievich Arseniev (1872-1930), publicado por primera vez en 1923, y la película homónima del director japonés Akira Kurosawa (1910-1998), lanzada en 1975. Estas obras reconstruyen tres expediciones realizadas por Arseniev a principios del siglo XX en la región siberiana del Ussuri que tuvieron como guía al cazador nómada de etnia gold Dersu Uzala, con quien el escritor construyó una profunda amistad. La elección de hacer dialogar en el mismo plan a dos modos complementares de conocimiento, arte y ciencia, se fundamenta en la concepción de Edgar Morin (2003b) de la literatura y el cine como escuelas de vida y de complejidad humana y en la visión de Claude Lévi- Strauss (2007) del arte como modelo reducido que favorece una mirada más abarcadora sobre los fenómenos. Inicialmente, pongo en relación mi investigación con los trabajos de Silmara Lídia Marton (2008) y Samir Cristino de Souza (2009), que analizaron las estrategias de construcción de conocimiento y de interacción con el mundo de un habitante de la Laguna de Piató (Municipio de Assú, Estado de Rio Grande do Norte, Brasil), Francisco Lucas da Silva, y muestro algunas analogías entre estas y las de Dersu Uzala, ambas productos de determinadas hibridaciones con el ambiente. A continuación, exploro las implicaciones cognitivas de la amistad de Arseniev con el cazador gold, metáfora/encarnación del diálogo posible entre saberes de matrices diferentes. En un tercer momento, dialogando con pensadores que se interrogaron sobre el trinomio hombre-naturaleza-representaciones y con las narrativas de Arseniev (1997) y Kurosawa (1975), reflexiono sobre las ideas de híbrido, de humano y no humano, de vivo y no vivo, de proximidad y distancia del sujeto con respecto a otros sistemas de lectura del mundo, de relación directa y mediada con lo real, de ambientes naturales urbanos y no urbanos. A seguir, incursiono en el libro de Arseniev y en el largometraje de Kurosawa intentando identificar qué factores más contribuyeron para configurar las estrategias de conocimiento y de interacción con el ambiente manifestadas por el explorador y por el cazador gold y, recursivamente, de qué forma esas estrategias contribuyeron a definir sus hibridaciones con el ambiente siberiano. Por último, a partir de las reflexiones tejidas a lo largo del trabajo, me interrogo sobre lo que ellas pueden decirnos sobre nuestra forma de interactuar con la naturaleza no humana y sobre el diálogo entre distintas formas de percibir, conocer y relacionarse con el mundo

O complexo geográfico em os sertões de Euclides da Cunha

The relation between geography and literature if has shown sufficiently promising.When considering that as much geography how much literature, constructs representations of the space from its speeches we find initially the point of interaction between both.In this direction, the workmanship "Os Sertões‖ of Euclides of the Wedge in allows them to argue where measured the existing specifications in a literary composition they can directly interest geography in the construction of its representations about the space.However to construct this approach, we take as north the conceptions of the complexity in which we weave the idea of that the workmanship if constitutes a geographic complex.We detach thus, the language of "Os Sertões‖ as one of the aspects that specify the complex in the Euclidean narrative and that it can interest geography in the production of its knowledge.As well as the language, the imagination is understood while an element that in makes possible them to analyze, to understand and to find the direction of the images made use in the space hinterland

O teatro de Elias Canetti em diálogo com a pós-modernidade

The purpose of this dissertation is to analyse the dramaturgic work of the Bulgarian author Elias Canetti, composed by the plays The Wedding, Comedy of Vanity and Their Days are Numbered, seeking to comprehend how the contemporary critic theories act on his trilogy, making a dialogue with theoretical references which may justify its approaching to the postmodernism. In this perspective, the theories by Jean-François Lyotard, Fredric Jameson and Jürgen Habermas contribute for a better comprehension of the postmodernity phenomenon. Undertaking Canetti’s notes and theatre with the philosophical concepts of Adorno’s negative aesthetics, we realise there is a space to reflect upon the theories which befell, like Foucault’s power relations in Micro-physics of Power and the discourses of resistance and deterritorialisation developed by Deleuze and Guattari in A Thousand Plateau and Anti-Oedipus. Even though Canetti’s plays were written between 1932 and 1956, all of them show a strong critic against modernism, and their characteristics did not help their recognition by the critics, which resulted in a rediscovery of Canetti’s plays after the author won the Nobel Prize in 1981.

Pirometamorfismo provocado por intrusões básicas cenozoicas em rochas da Bacia Potiguar, RN: integração de dados geológicos e petrofísicos

The Potiguar Basin is located in the Brazilian Equatorial Margin and presents sedimentary rocks affected by Cenozoic basic igneous intrusions, known as Macau Magmatism. The most prominent effect related to these intrusions is the formation of buchites, pyrometamorphic rocks that occur at very high temperatures and very low pressures in the sanidinite metamorphic facies. Through literature review, field observations, petrographic and petrophysical data, accessing the database of previous studies and results from this research, it was possible to characterize and estimate the effects produced in the thermal aureole of some hypabyssal bodies in the basin. The most relevant features associated with the intrusions are: compactation, hydraulic fracturing, partial melting and recrystallization of country rocks. According to the observed mineral occurrences, temperature of 800 to 1200 °C and pressure below 0,5 kbar were estimated at the contacts of the igneous bodies. The thermal modeling of the São João plug indicates thermal effects extending up to 150 m away from the contact and cooling time of approximately 265,000 years. After the peak of temperature, followed a cooling phase registered by remobilization and precipitation of minerals at low-temperature in faults, fractures and geodes, interpreted as derived from reactions with sedimentary rocks and metasomatic / hydrothermal fluids with abundant carbonatization and silicification.

Pirometamorfismo provocado por intrusões básicas cenozoicas em rochas da Bacia Potiguar, RN: integração de dados geológicos e petrofísicos

The Potiguar Basin is located in the Brazilian Equatorial Margin and presents sedimentary rocks affected by Cenozoic basic igneous intrusions, known as Macau Magmatism. The most prominent effect related to these intrusions is the formation of buchites, pyrometamorphic rocks that occur at very high temperatures and very low pressures in the sanidinite metamorphic facies. Through literature review, field observations, petrographic and petrophysical data, accessing the database of previous studies and results from this research, it was possible to characterize and estimate the effects produced in the thermal aureole of some hypabyssal bodies in the basin. The most relevant features associated with the intrusions are: compactation, hydraulic fracturing, partial melting and recrystallization of country rocks. According to the observed mineral occurrences, temperature of 800 to 1200 °C and pressure below 0,5 kbar were estimated at the contacts of the igneous bodies. The thermal modeling of the São João plug indicates thermal effects extending up to 150 m away from the contact and cooling time of approximately 265,000 years. After the peak of temperature, followed a cooling phase registered by remobilization and precipitation of minerals at low-temperature in faults, fractures and geodes, interpreted as derived from reactions with sedimentary rocks and metasomatic / hydrothermal fluids with abundant carbonatization and silicification.

Translocation of 99mTc labelled bacteria after intestinal ischemia and reperfusion

Ischemia and reperfusion of the small intestine disrupts gut barrier, causes bacterial translocation and activates inflammatory responses. An experimental study was planned to evaluate if 99mTc labelled Escherichia coli translocates to mesenteric lymph nodes, liver, spleen, lung and serum of rats submitted to mesenteric ischemia/reperfusion. Additionally, it was observed if the time of reperfusion influences the level of translocation. METHODS: Forty male Wistar rats underwent 45 minutes of gut ischemia by occlusion of the superior mesenteric artery. The translocation of labelled bacteria to different organs and portal serum was determined in rats reperfused for 30 minutes, 24 hours, sham(S) and controls(C), using radioactivity count and colony forming units/g (CFU). RESULTS: All the organs from rats observed for 24 hours after reperfusion had higher levels of radioactivity and positive cultures (CFU) than did the organs of rats reperfused for 30 minutes, C and S, except in the spleen (p<0,01). CONCLUSION: The results of this study indicated that intestinal ischemia/reperfusion led to bacterial translocation, mostly after 24 hours of reperfusion