Um olhar sobre o cotidiano e as re-definições espaciais no Bairro Potengi, Natal/RN

This work aims to conduct an analysis on the production of space and the dynamics between social agents that act and interact, albeit in different ways, in the production and re-production space in the Neighborhood Potengi in Natal, Rio Grande do Norte. The neighborhood is undergoing a process of dynamism undeniable and has a daily marked by heterogeneity, especially as a neighborhood in transition. So your analysis, from the perspective of the dialectical method, contributes to the understanding of the production space can be analyzed through the study of the forms and content, and may contribute to its real apprehension. After all, the city reflects forms, assumes functions, features and content that dynamic influences and is influenced by human relationships. Thus, this research seeks to analyze the production of space, based on the observation and study of the rich daily life of different social agents that operate within concrete quoted

As faces do corredor cultural de Mossoró-RN: cenários e práticas sociais

This work aims to understand the ways in which the social practices and the scenery within a public space located at the city centre of Mossoró - RN, named `The Cultural Corridor` , are constructed. The public space in question will be looked at and analyzed considering it`s components and specificities that, in relation to each other, work as a `public scenario`. The concept of `scenario` is the key for explaining the human actions in the physical space, that is, in the Cultural Corridor. This work also discusses about the action of the public in general and the political groups, and their relationship, within the context of the social practices related to the use of the Cultural Corridor`s space

Experience-dependent upregulation of multiple plasticity factors in the hippocampus during early REM sleep

Sleep is beneficial to learning, but the underlying mechanisms remain controversial. The synaptic homeostasis hypothesis (SHY) proposes that the cognitive function of sleep is related to a generalized rescaling of synaptic weights to intermediate levels, due to a passive downregulation of plasticity mechanisms. A competing hypothesis proposes that the active upscaling and downscaling of synaptic weights during sleep embosses memories in circuits respectively activated or deactivated during prior waking experience, leading to memory changes beyond rescaling. Both theories have empirical support but the experimental designs underlying the conflicting studies are not congruent, therefore a consensus is yet to be reached. To advance this issue, we used real-time PCR and electrophysiological recordings to assess gene expression related to synaptic plasticity in the hippocampus and primary somatosensory cortex of rats exposed to novel objects, then kept awake (WK) for 60 min and finally killed after a 30 min period rich in WK, slow-wave sleep (SWS) or rapid-eye-movement sleep (REM). Animals similarly treated but not exposed to novel objects were used as controls. We found that the mRNA levels of Arc, Egr1, Fos, Ppp2ca and Ppp2r2d were significantly increased in the hippocampus of exposed animals allowed to enter REM, in comparison with control animals. Experience-dependent changes during sleep were not significant in the hippocampus for Bdnf, Camk4, Creb1, and Nr4a1, and no differences were detected between exposed and control SWS groups for any of the genes tested. No significant changes in gene expression were detected in the primary somatosensory cortex during sleep, in contrast with previous studies using longer post-stimulation intervals (>180 min). The experience-dependent induction of multiple plasticity-related genes in the hippocampus during early REM adds experimental support to the synaptic embossing theory.