Color image magnification with interval-valued fuzzy sets

In this work we present a simple magnification algorithm for color images. It uses Interval-Valued Fuzzy Sets in such a way that every pixel has an interval membership constructed from its original intensity and its neighbourhood's one. Based on that interval membership, a block is created for each pixel, so this is a block expansion method.

Improving stamping tryout using variational analysis, FE simulations and robustness

The tryout process at an automotive sheet metal production plant is outlined and analysed with the aim of augmenting the process to improve robustness through an understanding of variation using Finite Element (FE) analysis and other tools. The result is tryout can produce a more robust stamping process.

Estimation of basis frequencies for time-varying SIMO channels : a second-order method

The complex exponential basis expansion model (CE-BEM) provides an accurate description for the time-varying (TV) channels encountered in mobile communications. Many blind channel identification and equalization approaches based on the CE-BEM require precise knowledge of the basis frequencies of TV channels. Existing methods for basis frequency estimation usually resort to the higher-order statistics of channel outputs and impose strict constraints on the source signal. In this paper, we propose a novel method to estimate the basis frequencies for blind identification and equalization of time-varying single-input multiple-output (SIMO) finite-impulse-response (FIR) channels. The proposed method exploits only the second-order statistics of channel outputs and does not require strong conditions on the source signal. As a result, it exhibits superior performance to the existing basis frequency estimation methods. The validity of our method is demonstrated by numerical simulations.

Laguerre Runge-Kutta-Fehlberg method for simulating laser pulse propagation in biological tissue

An efficient algorithm for solving the transient radiative transfer equation for laser pulse propagation in biological tissue is presented. A Laguerre expansion is used to represent the time dependency of the incident short pulse. The Runge–Kutta– Fehlberg method is used to solve the intensity. The discrete ordinates method is used to discretize with respect to azimuthal and zenith angles. This method offers the advantages of representing the intensity with a high accuracy using only a few Laguerre polynomials, and straightforward extension to inhomogeneous media. Also, this formulation can be easily extended for solving the 2-D and 3-D transient radiative transfer equations.

A construction method of interval-valued fuzzy sets for image processing

In this work we present a new construction method of IVFSs from Fuzzy Sets. We use these IVFSs for image processing. Concretely, in this contribution we introduce a new image magnification algorithm using IVFSs. This algorithm is based on block expansion and it is characterized by its simplicity.

Expansion of congested railway capacity using triple-track line operation based on hourly passenger demand

This paper proposes a method of improving level of service in congested urban railways by means of a triple-track line operation for a highly dense urban area with special travel demand characteristics. Where the future travel demand forecasts show sluggish growth or no growth at all, there is little to no incentives for heavy railway investments like quadruple-track extension and construction of new railway routes to alleviate current railway congestion problems. In such a situation, triple-track line operation can be the best alternative due to its moderate investment cost and ease in land acquisition for just an additional single track along the existing tracks. Our simulation investigation in one of the congested railway lines in Tokyo showed that triple track line operation increases railway capacity by 26% and shortens travel time by 38% in peak direction during morning peak hours. These results are encouraging and are useful for removing current railways problems in Tokyo and in similar urban situations elsewhere.

Expansion of human hematopoietic stem/progenitor cells on decellularized matrix scaffolds

Umbilical cord blood (UCB) is one of the richest sources for hematopoietic stem/progenitor cells (HSPCs), with more than 3000 transplantations performed each year for the treatment of leukemia and other bone marrow, immunological, and hereditary diseases. However, transplantation of single cord blood units is mostly restricted to children, due to the limited number of HSPC per unit. This unit develops a method to increase the number of HSPCs in laboratory conditions by using cell-free matrices from bone marrow cells that mimic 'human-body niche-like' conditions as biological scaffolds to support the ex vivo expansion of HSPCs. In this unit, we describe protocols for the isolation and characterization of HSPCs from UCB and their serum-free expansion on decellularized matrices. This method may also help to provide understanding of the biochemical organization of hematopoietic niches and lead to suggestions regarding the design of tissue engineering-based biomimetic scaffolds for HSPC expansion for clinical applications.

A facile method to enhance ferroelectric properties in PVDF nanocomposites

Poly(vinylidene fluoride) (PVDF)/nanoclay composites were prepared using melt compounding. The effect of acrylic rubber (ACM) as a compatibilizer on different polymorph formation and on the ferroelectric properties of nanocomposites were investigated. The intercalation and morphological structure of the samples were studied using X-ray diffraction (XRD) and transmission electron microscopy (TEM). The infrared spectroscopy and X-ray analysis revealed the coexistence of β and γ crystalline forms in PVDF-clay nanocomposite, while in partially miscible PVDF/ACM/clay hybrids, three polymorphs of α, β and γ coexisted. The coefficients of electric field-polarization (E-P) Taylor expansion were calculated based on the Lorentz theory. Using a genetic algorithm, complex dielectric susceptibilities as well as the dielectric constants for each sample were calculated and optimized. The predicted dielectric constants were found to be in good agreement with the experimental results. A dielectric constant of 16 (10 Hz) was obtained for PVDF/ACM/clay (90/10/5), which was 40% higher than that of the PVDF-clay (100/5) nanocomposite without ACM. The improved dielectric performance of the nanocomposites can be attributed to the compatibilizing effect of ACM, which facilitated the growth of β polymorph in the sample.

Enhanced Ex Vivo expansion of human hematopoietic progenitors on native and spin coated acellular matrices prepared from bone marrow stromal cells

The extracellular microenvironment in bone marrow (BM) is known to regulate the growth and differentiation of hematopoietic stem and progenitor cells (HSPC). We have developed cell-free matrices from a BM stromal cell line (HS-5), which can be used as substrates either in native form or as tissue engineered coatings, for the enhanced ex vivo expansion of umbilical cord blood (UCB) derived HSPC. The physicochemical properties (surface roughness, thickness, and uniformity) of native and spin coated acellular matrices (ACM) were studied using scanning and atomic force microscopy (SEM and AFM). Lineage-specific expansion of HSPC, grown on these substrates, was evaluated by immunophenotypic (flow cytometry) and functional (colony forming) assays. Our results show that the most efficient expansion of lineage-specific HSPC occurred on spin coated ACM. Our method provides an improved protocol for ex vivo HSPC expansion and it offers a system to study the in vivo roles of specific molecules in the hematopoietic niche that influence HSPC expansion.