A facile method to fabricate carbon nanostructures via the self-assembly of polyacrylonitrile/poly (methyl methacrylate-b-polyacrylonitrile) AB/B' type block copolymer/homopolymer blends

The self-assembly and high temperature behavior of AB/B′ type block copolymer/homopolymer blends containing polyacrylonitrile (PAN) polymers were studied for the first time. Here, microphase separated nanostructures were formed in the poly(methyl methacrylate-b-polyacrylonitrile) (PMMAN) block copolymer and their blends with homopolymer PAN at various blend ratios. Additionally, these nanostructures were transformed into porous carbon nanostructures by sacrificing PMMA blocks via pyrolysis. Spherical and worm like morphologies were observed in both TEM and AFM images at different compositions. The thermal and phase behavior examinations showed good compatibility between the blend components in all studied compositions. The PAN homopolymer (B′) with a comparatively higher molecular weight than the corresponding block (B) of the block copolymer is expected to exhibit ‘dry brush’ behavior in this AB/B′ type system. This study provides a basic understanding of the miscibility and phase separation in the PMMAN/PAN system, which is important in the nanostructure formation of bulk PAN based materials with the help of block copolymers to develop advanced functional materials.

Semantic data modelling and visualization using Noetica

Noetica is a tool for structuring knowledge about concepts and the reIationships between them. It differs from typical information systems in that the knowledge it represents is abstract, highly connected, and includes meta-knowledge (knowledge about knowledge). Noetica represents knowledge using a strongly typed graph data model. By providing a rich type system it is possible to represent conceptual information using formalized structures. A class hierarchy provides a basic classification for all objects. This allows for a consistency of representation that is not often found in `free' semantic networks, and gives the ability to easily extend a knowledge model while retaining its semantics. Visualization and query tools are provided for this data model. Visualization can be used to explore complete sets of link-classes, show paths while navigating through the database, or visualize the results of queries. Noetica supports goal-directed queries (a series of user-supplied goals that the system attempts to satisfy in sequence) and pathfinding queries (where the system finds relationships between objects in the database by following links).

The type II secretion system and its ubiquitous lipoprotein substrate, SsIE are required for biofilm formation and virulence of enteropathogenic escherichia coli

Enteropathogenic Escherichia coli (EPEC) is a major cause of diarrhea in infants in developing countries. We have identified a functional type II secretion system (T2SS) in EPEC that is homologous to the pathway responsible for the secretion of heat-labile enterotoxin by enterotoxigenic E. coli. The wild-type EPEC T2SS was able to secrete a heat-labile enterotoxin reporter, but an isogenic T2SS mutant could not. We showed that the major substrate of the T2SS in EPEC is SslE, an outer membrane lipoprotein (formerly known as YghJ), and that a functional T2SS is essential for biofilm formation by EPEC. T2SS and SslE mutants were arrested at the microcolony stage of biofilm formation, suggesting that the T2SS is involved in the development of mature biofilms and that SslE is a dominant effector of biofilm development. Moreover, the T2SS was required for virulence, as infection of rabbits with a rabbit-specific EPEC strain carrying a mutation in either the T2SS or SslE resulted in significantly reduced intestinal colonization and milder disease.

Neural network and interval type-2 fuzzy system for stock price forecasting

Stock price forecast has long been received special attention of investors and financial institutions. As stock prices are changeable over time and increasingly uncertain in modern financial markets, their forecasting becomes more important than ever before. A hybrid approach consisting of two components, a neural network and a fuzzy logic system, is proposed in this paper for stock price prediction. The first component of the hybrid, i.e. a feedforward neural network (FFNN), is used to select inputs that are highly relevant to the dependent variables. An interval type-2 fuzzy logic system (IT2 FLS) is employed as the second component of the hybrid forecasting method. The IT2 FLS’s parameters are initialized through deployment of the k-means clustering method and they are adjusted by the genetic algorithm. Experimental results demonstrate the efficiency of the FFNN input selection approach as it reduces the complexity and increase the accuracy of the forecasting models. In addition, IT2 FLS outperforms the widely used type-1 FLS and FFNN models in stock price forecasting. The combination of the FFNN and the IT2 FLS produces dominant forecasting accuracy compared to employing only the IT2 FLSs without the FFNN input selection.

Structural classification of proteins through amino acid sequence using interval type-2 fuzzy logic system

This paper introduces a new multi-output interval type-2 fuzzy logic system (MOIT2FLS) that is automatically constructed from unsupervised data clustering method and trained using heuristic genetic algorithm for a protein secondary structure classification. Three structure classes are distinguished including helix, strand (sheet) and coil which correspond to three outputs of the MOIT2FLS. Quantitative properties of amino acids are used to characterize the twenty amino acids rather than the widely used computationally expensive binary encoding scheme. Amino acid sequences are parsed into learnable patterns using a local moving window strategy. Three clustering tasks are performed using the adaptive vector quantization method to derive an equal number of initial rules for each type of secondary structure. Genetic algorithm is applied to optimally adjust parameters of the MOIT2FLS with the purpose of maximizing the Q3 measure. Comprehensive experimental results demonstrate the strong superiority of the proposed approach over the traditional methods including Chou-Fasman method, Garnier-Osguthorpe-Robson method, and artificial neural network models.

An interval type-2 fuzzy logic system-based method for prediction interval construction

This paper introduces a new non-parametric method for uncertainty quantification through construction of prediction intervals (PIs). The method takes the left and right end points of the type-reduced set of an interval type-2 fuzzy logic system (IT2FLS) model as the lower and upper bounds of a PI. No assumption is made in regard to the data distribution, behaviour, and patterns when developing intervals. A training method is proposed to link the confidence level (CL) concept of PIs to the intervals generated by IT2FLS models. The new PI-based training algorithm not only ensures that PIs constructed using IT2FLS models satisfy the CL requirements, but also reduces widths of PIs and generates practically informative PIs. Proper adjustment of parameters of IT2FLSs is performed through the minimization of a PI-based objective function. A metaheuristic method is applied for minimization of the non-linear non-differentiable cost function. Performance of the proposed method is examined for seven synthetic and real world benchmark case studies with homogenous and heterogeneous noise. The demonstrated results indicate that the proposed method is capable of generating high quality PIs. Comparative studies also show that the performance of the proposed method is equal to or better than traditional neural network-based methods for construction of PIs in more than 90% of cases. The superiority is more evident for the case of data with a heterogeneous noise. © 2014 Elsevier B.V.

Medical data classification using interval type-2 fuzzy logic system and wavelets

This paper introduces an automated medical data classification method using wavelet transformation (WT) and interval type-2 fuzzy logic system (IT2FLS). Wavelet coefficients, which serve as inputs to the IT2FLS, are a compact form of original data but they exhibits highly discriminative features. The integration between WT and IT2FLS aims to cope with both high-dimensional data challenge and uncertainty. IT2FLS utilizes a hybrid learning process comprising unsupervised structure learning by the fuzzy c-means (FCM) clustering and supervised parameter tuning by genetic algorithm. This learning process is computationally expensive, especially when employed with high-dimensional data. The application of WT therefore reduces computational burden and enhances performance of IT2FLS. Experiments are implemented with two frequently used medical datasets from the UCI Repository for machine learning: the Wisconsin breast cancer and Cleveland heart disease. A number of important metrics are computed to measure the performance of the classification. They consist of accuracy, sensitivity, specificity and area under the receiver operating characteristic curve. Results demonstrate a significant dominance of the wavelet-IT2FLS approach compared to other machine learning methods including probabilistic neural network, support vector machine, fuzzy ARTMAP, and adaptive neuro-fuzzy inference system. The proposed approach is thus useful as a decision support system for clinicians and practitioners in the medical practice. copy; 2015 Elsevier B.V. All rights reserved.

Multi-output interval type-2 fuzzy logic system for protein secondary structure prediction

A new multi-output interval type-2 fuzzy logic system (MOIT2FLS) is introduced for protein secondary structure prediction in this paper. Three outputs of the MOIT2FLS correspond to three structure classes including helix, strand (sheet) and coil. Quantitative properties of amino acids are employed to characterize twenty amino acids rather than the widely used computationally expensive binary encoding scheme. Three clustering tasks are performed using the adaptive vector quantization method to construct an equal number of initial rules for each type of secondary structure. Genetic algorithm is applied to optimally adjust parameters of the MOIT2FLS. The genetic fitness function is designed based on the Q3 measure. Experimental results demonstrate the dominance of the proposed approach against the traditional methods that are Chou-Fasman method, Garnier-Osguthorpe-Robson method, and artificial neural network models.

Mass spectrometry-based proteomic data for cancer diagnosis using interval type-2 fuzzy system

An interval type-2 fuzzy logic system is introduced for cancer diagnosis using mass spectrometry-based proteomic data. The fuzzy system is incorporated with a feature extraction procedure that combines wavelet transform and Wilcoxon ranking test. The proposed feature extraction generates feature sets that serve as inputs to the type-2 fuzzy classifier. Uncertainty, noise and outliers that are common in the proteomic data motivate the use of type-2 fuzzy system. Tabu search is applied for structure learning of the fuzzy classifier. Experiments are performed using two benchmark proteomic datasets for the prediction of ovarian and pancreatic cancer. The dominance of the suggested feature extraction as well as type-2 fuzzy classifier against their competing methods is showcased through experimental results. The proposed approach therefore is helpful to clinicians and practitioners as it can be implemented as a medical decision support system in practice.

A systematic design of interval type-2 fuzzy logic system using extreme learning machine for electricity load demand forecasting

This paper presents a novel design of interval type-2 fuzzy logic systems (IT2FLS) by utilizing the theory of extreme learning machine (ELM) for electricity load demand forecasting. ELM has become a popular learning algorithm for single hidden layer feed-forward neural networks (SLFN). From the functional equivalence between the SLFN and fuzzy inference system, a hybrid of fuzzy-ELM has gained attention of the researchers. This paper extends the concept of fuzzy-ELM to an IT2FLS based on ELM (IT2FELM). In the proposed design the antecedent membership function parameters of the IT2FLS are generated randomly, whereas the consequent part parameters are determined analytically by the Moore-Penrose pseudo inverse. The ELM strategy ensures fast learning of the IT2FLS as well as optimality of the parameters. Effectiveness of the proposed design of IT2FLS is demonstrated with the application of forecasting nonlinear and chaotic data sets. Nonlinear data of electricity load from the Australian National Electricity Market for the Victoria region and from the Ontario Electricity Market are considered here. The proposed model is also applied to forecast Mackey-glass chaotic time series data. Comparative analysis of the proposed model is conducted with some traditional models such as neural networks (NN) and adaptive neuro fuzzy inference system (ANFIS). In order to verify the structure of the proposed design of IT2FLS an alternate design of IT2FLS based on Kalman filter (KF) is also utilized for the comparison purposes.

Training of interval type-2 fuzzy logic system using extreme learning machine for load forecasting

Extreme learning machine (ELM) is originally proposed for single- hidden layer feed-forward neural networks (SLFN). From the functional equivalence of fuzzy logic systems and SLFN, the fuzzy logic systems can be interpreted as a special case of SLFN under some mild conditions. Hence the fuzzy logic systems can be trained using SLFN's learning algorithms. Considering the same equivalence, ELM is utilized here to train interval type-2 fuzzy logic systems (IT2FLSs). Based on the working principle of the ELM, the parameters of the antecedent of IT2FLSs are randomly generated while the consequent part of IT2FLSs is optimized using Moore-Penrose generalized inverse of ELM. Application of the developed model to electricity load forecasting is another novelty of the research work. Experimental results shows better forecasting performance of the proposed model over the two frequently used forecasting models.

Modelling and analysis of type 4 wind turbine generator system for utilization in frequency regulation studies

Green energy targets for coming decades advocates high penetration of wind energy in main energy matrix which also pose incendiary threat to stability and reliability of modern electric grid if their dynamic performance aspects are not assessed beforehand. Considering increasing interest in dynamic performance along with ancillary service assessment related to frequency regulation, development of suitable generic modeling has gained high priority. This paper presents modeling of type 4 full converter wind turbine generator system suitable for frequency regulation focusing on active power control. Complete model is a modification of WECC generic model with additional aerodynamic and pitch control model. Descriptions of individual sub models are presented and performance results are compared manufacturer specific GE type 4 WTG generic model by means of simulations in the MATLAB ® Power System Block set.

Hybrid model for the training of interval type-2 fuzzy logic system

In this paper, a hybrid training model for interval type-2 fuzzy logic system is proposed. The hybrid training model uses extreme learning machine to tune the consequent part parameters and genetic algorithm to optimize the antecedent part parameters. The proposed hybrid learning model of interval type-2 fuzzy logic system is tested on the prediction of Mackey-Glass time series data sets with different levels of noise. The results are compared with the existing models in literature; extreme learning machine and Kalman filter based learning of consequent part parameters with randomly generated antecedent part parameters. It is observed that the interval type-2 fuzzy logic system provides improved performance with the proposed hybrid learning model.