An intraspecific killing in adult Pacific reef egrets (Egretta sacra)

Intraspecific killing without cannibalism is rare in birds. I report an observation of an adult Pacific Reef Egret (Egretta sacra) killing an adult conspecific at One Tree Island, Great Barrier Reef, Australia. The motivation and context for the killing were not apparent. To the best of my knowledge, this is the first report of intraspecific killing in Pacific Reef Egrets.

Ethical transnational corporate activity at home and abroad: A proposal for reforming continuous disclosure obligations in Australia and the United States

Multinational Corporations establish operations in states with lower legal and ethical standards in areas including the environment, wages, labor standards, human rights, corruption, and company taxation. Corporate law scholars cannot be indifferent to the horrific consequences of these lax standards. From contributing to rapes and violent incidents stemming from trade in conflict minerals in the Congo to the killing of workers due to poor conditions in garment manufacturing units in Bangladesh, multinational corporations exploit conditions in developing countries abroad without disclosing their actions at home. We advance a normative argument to clarify and strengthen the existing model of disclosure-based regulation to hold MNCs accountable. We argue that, since the core expectations held by shareholders of companies are the same whether they are operating within our borders or externally, a harmonization of disclosure obligations imposed by law would be a more flexible and less costly solution. We posit that a broader reading of the disclosure obligations of companies under existing legislation like the Reg. S-K in the United States, the continuous disclosure rules under * Dean and Professor of Law, University of Newcastle Law School. Sandeep Gopalan would like to thank Terrie Troxel, Jack Tatom, Professor Bill Wilhelm, and the Networks Financial Institute at Indiana State University College of Business for their valuable support in conducting research for this article. We are also grateful to Audrey Son, Bassam Khawaja, and the editorial staff of the Columbia Human Rights Law Review for their excellent editorial work. ** Solicitor and doctoral candidate, University of Newcastle Law School. 2 COLUMBIA HUMAN RIGHTS LAW REVIEW [46.2:1 the Australian Corporations Act 2001, and listing rules such as those adopted by the Australian Securities Exchange and the New York Stock Exchange would require the disclosure of material corporate practices outside our national borders.

The resilience of West Sumatran women: historical, social and cultural impacts

In 1965–66, an effort by the central government to eradicate the Indonesian Communist Party and its sympathizers resulted in the killing of thousands of people across Indonesia who were suspected of being members of the party as well as others who were associates of known members. The violence witnessed or experienced by those whose family members were targeted was a major force in shaping their later experience. This paper discusses the experience of women in West Sumatra, Indonesia who experienced the events of 1965–66 from a life course perspective and focuses on their efforts to adapt in the following years. Many of these women displayed considerable resilience in overcoming the social constraints that resulted from being labelled a Communist or Communist sympathizer. The paper, based on ethnographic research in West Sumatra, discusses the formation of resilience among these women and describes the ways in which they were able to adjust to the social and historical context in which they found themselves.

Pakistan-China bilateral relations 2001-2011 : a deepening but cautious partnership

Last year (2011) marked the sixtieth anniversary of the establishment of diplomatic relations between Pakistan and China. The bilateral relationship has deepened significantly since 1951, with both countries benefiting from this relationship. However, Pakistan would like to deepen it even further, while China is more pragmatic and cautious. There are irritants, notably the killing of Chinese citizens, the presence of Uighur militants in Pakistan and their different interests in Afghanistan, which could put some stress on the relationship. While the relationship will continue to grow, China is not about to displace the US as Pakistan’s major economic and military aid provider.

Can we civilize the Aborigines without killing them? : Florence Nightingale's influence on Bishop Salvado

In 1859 English public health nurse Florence Nightingale decided to conduct a study of the mortality rates in ‘native schools’ in Britain’s colonies. Since the 1837 publication of the House of Commons Report on the impact of British settlement on native people’s, there had been a speculative discourse about the decline of the Aboriginal populations in the colonies; concerns about Aboriginal health and welfare were debated frequently. New Norcia was included in Nightingale’s study and played a big part in Nightingale’s conclusions.
This paper will discuss the study and New Norcia’s participation in it, with particular attention to the correspondence, questionnaires and reports that travelled between Salvado and Nightingale. This unique archive reveals not only Nightingale’s concern about the relationship between civilizing and Aboriginal ill-health in the colonies, but also shed’s light on Salvado’s remarkable insight into this delicate and fraught relationship. By analysing Salvado’s statistical collections and reports for Nightingale’s study on New Norcia’s Aboriginal residents, it is possible to understand that Salvado evaluated and repudiated the influential theory that the Aborigines were inevitably a dying race.

Defacing the acquisitions: a museal-analysis of serial killing horror in cinema

Explores the relationship between serial killing and affect as a form of cinematic horror that repositions the viewer away from the logic of reason through a dismantling of subjectivity via 'modifications' to the body. The chapter has a particular attention to the representation of serial killing in the museum space - theoretically a locus of modern rationality and order- to argue that the museum can be philsophically understood as functioning to detatch desire from subjective formation and fixed encoding of identies. The chapter draws on philosopher Gilles Deleuze and theorists Anna Powell and Steven Shaviro.

Killing the father, Parmenides: on Lacan’s anti-philosophy

This paper examines the historical claims about philosophy, dating back to Parmenides, that we argue underlie Jacques Lacan’s polemical provocations in the mid-1970s that his position was an “anti-philosophie”. Following an introduction surveying the existing literature on the subject, in part ii, we systematically present the account of classical philosophy Lacan has in mind when he declares psychoanalysis to be an antiphilosophy after 1975, assembling his claims about the history of ideas in Seminars XVII and XX in ways earlier contributions of this subject have not systematically done. In part iii, focusing upon Lacan’s remarkable reading of Descartes’ break with premodern philosophy—but touching on Lacan’s readings of Hegel and (in a remarkable confirmation of Lacan’s “Parmenidean” conception of philosophy) the early Wittgenstein—we examine Lacan’s positioning of psychoanalysis as a legatee of the Cartesian moment in the history of western ideas, nearly-contemporary with Galileo’s mathematization of physics and carried forwards by Kant’s critical philosophy and account of the substanceless subject of apperception. In different terms than Slavoj Žižek, we propose that it is Lacan’s famous avowal that the subject of the psychoanalysis is the subject first essayed by Descartes in The Meditations on First Philosophy as confronting an other capable of deceit (as against mere illusion or falsity) that decisively measures the distance between Lacan’s unique “antiphilosophy” and the forms of later modern linguistic and cultural relativism whose hegemony Alain Badiou has decried, at the same time as it sets Lacan’s antiphilosophy apart from the Parmenidean legacy for which thinking and being could be the same.

Euthanasia and assisted suicide : a liberal approach versus the traditional moral view

Within the context of the debate over the recent suspended sentence given to John Stuart Godfrey by Underwood J in the Supreme Court of Tasmania for assisting his elderly mother with her suicide, this article examines some of the more popular arguments for and against the moral acceptability of euthanasia and assisted suicide. This article considers the arguments put forward on the “difference principle” by Rachels and Nesbitt before critically examining the liberal approach to the euthanasia issue as proposed by Kuhse. It is argued that whilst Kuhse is correct to reject the difference principle, she does so for the wrong reasons. The penultimate section of the article provides an overview of the traditional moral view against killing. The final part assesses whether the arguments put forward by proponents of the liberal approach are capable of overcoming this view.

The execution of Van Nguyen: an Australian perspective

The execution of 25-year-old Melbourne man, Van Nguyen, by Singaporean authorities on 2 December 2005 for attempting to smuggle 400 grams of heroin out of Singapore was cruel. It was also futile. Yet, there are three important lessons that can be learned from his killing. The first lesson is that if Australia is to exert genuine moral pressure on nations to abolish the death penalty it must do so in a principled manner, rather than making expedient pleas when Australians happen to be on the wrong end of the cruel practice. Secondly, sentencing practice in Australia, while not condoning capital punishment, is unjustifiably punitive and we should ameliorate the harshness of some of our sentencing laws. Finally, the death of Nguyen, while tragic, was no more tragic than the millions of other preventable deaths that occur daily throughout the world. The compassion displayed toward Nguyen should be used as a catalyst for enlarging our sympathy gland in relation to all preventable deaths. I now discuss these in further detail.

The pyjama girl mystery : a true story of murder, obsession and lies

The pyjama girl was an unknown woman, found dumped by a road nesrl Albury in 1934. She had been brutally murdered. Who was she, and who killed her, become Australia's great unsolved crime for decades. The body was preserved in formalin, her image circulated around the world. The mystery fascinated the nation and, for some, became an obsession. Ten years later, the body was identified and a man was convicted of her manslaughter. The case, it seemed, was neatlty solved. But this 'solution', advanced by police, accepted by the courts and the media, and since repeated endlessly, was a lie. Behind the lie is a troubling story of murder and obsession, of a wild conspiracy theory, of police corruption and a miscarriage of justice, and of a real killing which floated free from reality and became a myth.

A mystery to the medical world : Florence Nightingale, Rosendo Salvado and the risk of civilisation

In 1860 Florence Nightingale conducted a study on the mortality rates of indigenous children attending native colonial schools across the British Empire. Her study was driven by the question: ‘Can we civilise the natives without killing them?’ One colonial school that participated in the survey was New Norcia Benedictine mission in Western Australia. When Rosendo Salvado, the mission’s superintendent, responded, he drew on his daily encounters with the Yuat people, his statistics on the mission residents and his Benedictine philosophy of civilisation and conversion of colonised peoples. The correspondence between Salvado and Nightingale took place in the climate of intense debates about Aboriginal health, colonisation and extinction in Britain and the colonies. While many settlers and colonial observers understood Aboriginal depopulation to be the result of either the vices and diseases of unprincipled Europeans or an unstoppable destiny, whether Divine Providence or natural selection, Nightingale and Salvado shared a belief in practical solutions to what they understood to be a practical problem. Their collaboration is an example of the humanitarian opposition to the racial pessimism of Social Darwinism. They both sought to use the recently influential intellectual discipline of social statistics to support their conviction that Aborigines, if patiently and carefully handled, would survive the admittedly risky process of civilisation.

Investigation of the plasmodium falciparum food vacuole through inducible expression of the chloroquine resistance transporter (PfCRT)

Haemoglobin degradation during the erythrocytic life stages is the major function of the food vacuole (FV) of Plasmodium falciparum and the target of several anti-malarial drugs that interfere with this metabolic pathway, killing the parasite. Two multi-spanning food vacuole membrane proteins are known, the multidrug resistance protein 1 (PfMDR1) and Chloroquine Resistance Transporter (PfCRT). Both modulate resistance to drugs that act in the food vacuole. To investigate the formation and behaviour of the food vacuole membrane we have generated inducible GFP fusions of chloroquine sensitive and resistant forms of the PfCRT protein. The inducible expression system allowed us to follow newly-induced fusion proteins, and corroborated a previous report of a direct trafficking route from the ER/Golgi to the food vacuole membrane. These parasites also allowed the definition of a food vacuole compartment in ring stage parasites well before haemozoin crystals were apparent, as well as the elucidation of secondary PfCRT-labelled compartments adjacent to the food vacuole in late stage parasites. We demonstrated that in addition to previously demonstrated Brefeldin A sensitivity, the trafficking of PfCRT is disrupted by Dynasore, a non competitive inhibitor of dynamin-mediated vesicle formation. Chloroquine sensitivity was not altered in parasites over-expressing chloroquine resistant or sensitive forms of the PfCRT fused to GFP, suggesting that the PfCRT does not mediate chloroquine transport as a GFP fusion protein.

Host defense at the ocular surface

Microbial infections of the cornea frequently cause painful, blinding and debilitating disease that is often difficult to treat and may require corneal transplantation. In addition, sterile corneal infiltrates that are associated with contact lens wear cause pain, visual impairment and photophobia. In this article, we review the role of Toll-Like Receptors (TLR) in bacterial keratitis and sterile corneal infiltrates, and describe the role of MD-2 regulation in LPS responsiveness by corneal epithelial cells. We conclude that both live bacteria and bacterial products activate Toll-Like Receptors in the cornea, which leads to chemokine production and neutrophil recruitment to the corneal stroma. While neutrophils are essential for bacterial killing, they also cause tissue damage that results in loss of corneal clarity. These disparate outcomes, therefore, represent a spectrum of disease severity based on this pathway, and further indicate that targeting the TLR pathway is a feasible approach to treating inflammation caused by live bacteria and microbial products. Further, as the P. aeruginosa type III secretion system (T3SS) also plays a critical role in disease pathogenesis by inducing neutrophil apoptosis and facilitating bacterial growth in the cornea, T3SS exotoxins are additional targets for therapy for P. aeruginosa keratitis.

The mechanisms of Chansu in inducing efficient apoptosis in colon cancer cells

Chansu is one of the most widely used traditional Chinese medicines in China, Japan, and other Southeast Asian countries primarily for antipain, anti-inflammation, and recently anticancer. Over 10 recipes and remedies contained Chansu, which are easily available in pharmacies and hospitals, but the mechanisms of action were not clearly articulated. In the present study, Cinobufagin (CBF), the major compound of Chansu, was employed as a surrogate marker to determine its ability in inducing cancer cell death. As expected, CBF has significant cancer-killing capacity for a range of cancers, but such ability differs markedly. Colon and prostate cancers are more sensitive than skin and lung cancers. Interestingly, cancer cells die through apoptotic pathway either being biphasic caspase- 3-dependent (HCT116) or independent (HT29). Multipathway analysis reveals that CBF-induced apoptosis is likely modulated by the hypoxia-inducing factor-1 alpha subunit (HIF-1