Some morphometric and biochemical features of ready-to-migrate silver and pre-migratory yellow stages of the shortfin eel of south-eastern Australian waters

The mean total length (L_T), mass and age of ready to migrate female silver shortfin eels Anguilla australis from the Hopkins River estuary and the mouth of the Merri River in south-eastern Australia, were 83·2 ± 1·2 cm, 1051 ± 51 g, and 17·2 ± 1·79 years, respectively. The eye index (I_E) of the silver shortfin eels was < 5·2 (mean 7·64 ± 0·29) and differed significantly from that of the yellow shortfin eels collected from two other sites. The I_E increased with L_T (mm) and was related by log I_E= 2·656 log L_T6·925. The per cent moisture, protein and ash content of the liver of silver shortfin eels was significantly lower than in yellow shortfin eels, but lipid content was significantly higher in the former (35·5 ± 2·0%). The mean mass μg mg lipid ‾) of saturates (230·4 ± 2·6 v. 181·7 ±2·6), monoenes (367·4 ± 6·3 v. 290·8 ± 8·9) and PUFA (177·3 ± 5·3 v. 159·7 ± 4·6) in muscle was significantly higher, and the great majority of individual fatty acids was found also in higher quantities in silver shortfin eels. In the liver, the PUFA found in the highest quantity was 22:6n-3, except in shortfin eels from Hopkins River estuary, and the amount of 18:2n-6 in the liver of silver shortfin eels was significantly higher than that in yellow shortfin eels but the reverse was true of 20:4n-6. In both muscle and liver tissues the saturate 16:0 and the monoene 18:ln-9 collectively accounted for >50% of all the fatty acids in the lipid.

What is "inflammation"? Are we ready to move beyond Celsus?

Inflammation, a term coined by the ancients, is widely used in sports medicine. But what is meant when a clinician tells a patient that symptoms are probably due to inflammation? The question of whether inflammation is helpful or harmful to healing can only be answered after inflammation is defined. This brief analysis of inflammation reveals that the term’s definition has changed dramatically since it was first used by Celsus nearly 2000 years ago. The definition also depends on the type of lens the viewer is using—whether it be clinical, cellular, or molecular.

Contact pressure evolution and its relation to wear in sheet metal forming

For a given sheet metal forming process, an accurate determination of the contact pressure distribution is an essential step towards the estimation of tool life. This investigation utilizes finite element (FE) analysis to model and explain the evolution and distribution of contact pressure over the die radius, throughout the duration of a channel forming process. It was found that a typical two-peak steady-state contact pressure response exists for the majority of the process. However, this was preceded by an initial transient response, characterized by extremely large and localized contact pressures, which were more than double the magnitude of the steady-state peak pressure. The validity of the predicted contact pressure behavior was assessed via detailed numerical analysis and by examining the wear response of an experimental stamping operation. The experimental results revealed that the high contact pressure zones of the transient response corresponded to a severe galling wear mechanism. Therefore, the transient response may be of primary significance to the tool wear response; thus questioning the applicability of traditional bending-under-tension wear tests for sheet metal stamping processes. Finally, a parametric study was conducted, examining the influence of the major process parameters on the steady-state and peak transient contact pressures, using the developed FE model. It was found that the bend ratio and the blank material ultimate tensile strength had the most influence on the peak contact pressures. The main process-related parameters, friction coefficient and blank holder force, were found to have only a minor influence.

Deformation and frictional heating in relation to wear in sheet metal stamping

In the automotive industry, press production rates often need to be reduced in order to minimize tool wear issues and successfully stamp advanced high strength steels. This indicates that heating affects may be important. This paper examines friction and deformational heating at the die radius during sheet metal stamping, using finite element analysis. The results show that high temperatures, of up to 130°C, can occur at the die radius surface. Such behavior has not been previously reported in the literature, for what is expected to be ‘cold’ sheet metal stamping conditions. It will be shown that the temperature rise is due to the increased contact stresses and increased plastic work, associated with stamping AHSS. Consequently, new insights into the local contact conditions in sheet metal stamping were obtained. The outcomes of this work may impact the wear models and tests employed for future tool wear analyses in sheet metal stamping.

"Ready to acquire": the IT resources required for a growth-by-acquisition business strategy

This article describes the experiences of Danisco (a global food ingredients company) as it followed a growth-by-acquisition business strategy, focusing on how a new CIO built the IT resources to ensure the IT organization was "ready to acquire." We illustrate how these IT capabilities expedited the IT integration following two acquisitions, one of which involved Danisco expanding the scale of its business and the other extending the scope. Based on insights gained from Danisco, we provide lessons for CIOs to realize business benefits when managing post-acquisition IT integration.

Knowledge, attitudes and self-care practices related to sun protection among secondary students in Australia

The aim of this research was to ascertain changes in sun-related knowledge, attitudes and self-care practices among Australian secondary school students between 1993 and 1996. Two cross-sectional surveys of sun-related attitudes, beliefs and behavior of young people aged 12–17 years of age, were conducted in 1993 and 1996. Over 80% of adolescents at both time periods knew about the issues related to skin cancer prevention, frequency of burning and burning on cloudy days. Adolescent attitudes had shifted positively in the areas of staying inside in 1996 [relative risk (RR): 1.13; 95% confidence interval (CI): 1.09–1.17] and staying under shade in 1996 (RR: 1.16; 95% CI: 1.13–1.18). Desire for a moderate or dark tan was lower in 1996 (45%) than in 1993 (50%). Respondents reported that they were less likely to wear brief clothing to get a suntan in 1996 (RR: 0.81; 95% CI: 0.78–0.84) and were significantly more likely to stay in the shade in 1996 (RR: 1.19; 95% CI: 1.16–1.23). We conclude that there has been a shift in attitudes towards use of shade and avoidance of unnecessary exposure, and away from use of sunscreens and sunglasses. The results suggest that adolescents may be more ready to accept structural changes that move desired activities out of the sun.

Contact pressure and wear in sheet metal forming - an FEM analysis

Wear is the principal cause of tool failure in most sheet metal forming processes. It is well known that the contact pressure between the blank and the tool has a large influence on the wear of the tool, and hence the tool life. This investigation utilises the finite element method to analyse the contact pressure distribution over the die radius for a particular deep drawing process. Furthermore, the evolution of the predicted contact pressure distribution throughout the entire stroke of the punch is also examined. It was found that the majority of the process shows a steady state pressure distribution, with two characteristic peaks over the die radius, at the beginning and end of the sheet contact area. Interestingly, the initial transient contact pressure response showed extremely high localised peak pressures; more than twice that of the steady state peaks. Results are compared to wear reported in the literature, during similar experimental deep drawing processes. Finally, the significance and effect of the results on wear and wear-testing techniques are discussed.

Teaching journalism students and regional reporters how to work with cultural diversity

This paper examines the effectiveness of a set of curriculum materials developed for a Reporting Diversity and Integration Project tailored for Australian journalists and journalism students. The materials take a problem-based learning (PBL) approach to a hypothetical case study that involves Muslim netballers being banned from competition because they want to wear headscarves during play. Deferring to ideas developed by Russian psychologist, Leo Vygotsky, we proposed a few ‘scaffolding’ strategies to support student learning. The material was trialed with 30 first-year Deakin University journalism students and 30 regional journalists. The responses showed that both groups felt the materials we added to the curriculum resources, which provided information on Muslim women and the headscarf, affected how they would write the story. They also thought it was important to provide this kind of information for readers. This paper argues that providing cultural information in an accessible format for students and journalists in newsrooms should be integral to education and training materials designed to improve media coverage of cultural diversity issues.

Tool wear in sheet metal stamping

This paper discusses our recent research on wear at the die radius in sheet metal stamping. According to wear theory, contact pressure and sliding distance are the two dominant factors in determining sliding wear. We applied the finite element analysis to accurately quantify the contact pressure and sliding distance at the die radius in sheet metal stamping. The results were then applied to analyze sliding wear at the die radius. We found that a typical two-peak steady-state contact pressure response exists during a channel forming process. The steady-state contact pressure response was preceded by an initial transient response, which produced extremely large and localized contact pressures. We proposed a method to numerically quantify the sliding distance, which was applied to examine the contact sliding distance at the die radius. Correlating the contact pressure and sliding distance, a new insight into the wear/galling that occurs at the die radius in sheet metal stamping was gained. The results show that the region close to zero degrees on the die radius is likely to experience the most wear, with the identified transient stage contributing to a large proportion of the total wear.

Pathways to new drug discovery in neuropsychiatry

There is currently a crisis in drug discovery for neuropsychiatric disorders, with a profound, yet unexpected drought in new drug development across the spectrum. In this commentary, the sources of this dilemma and potential avenues to redress the issue are explored. These include a critical review of diagnostic issues and of selection of participants for clinical trials, and the mechanisms for identifying new drugs and new drug targets. Historically, the vast majority of agents have been discovered serendipitously or have been modifications of existing agents. Serendipitous discoveries, based on astute clinical observation or data mining, remain a valid option, as is illustrated by the suggestion in the paper by Wahlqvist and colleagues that treatment with sulfonylurea and metformin reduces the risk of affective disorder. However, the identification of agents targeting disorder-related biomarkers is currently proving particularly fruitful. There is considerable hope for genetics as a purist, pathophysiologically valid pathway to drug discovery; however, it is unclear whether the science is ready to meet this promise. Fruitful paradigms will require a break from the orthodoxy, and creativity and risk may well be the fingerprints of success.

To the very ground of meaning, to vary the ground of meaning

Parody may be understood as the absorption of a revolutionary impulse into the everyday production of meaning as continuous variation and soft subversion. Considered in this way, parody is transformative because it operates on the components within a system of meaning and/or the context, logic or spatial perspective that grounds the possibility of meaning. It is the conditions under which shared meaning, sense and sensation depend that I aim to unpack in order to suggest the ways in which parody can alter a person’s relationship to the world. By approaching parody as a mode of lived abstraction and as an embodied approach to affective self-organisation, body-environment co-construction and a challenge to identity, it becomes possible to move from formal concerns that have characterised parody to a set of transformative practices. Thus parody indicates where the anchors of embodied, embedded, extended, enacted and affective are dug in and hold identity and the ground of meaning in a steady state. This paper will examine how parody moves from the impulse to overthrow and invert — ‘Beneath the street, The beach’—to a collective impulse that moves the ground of meaning into a reconfigurative process that is allows totalised systems of meaning to collide and intersect. What is left is not the rubble and ruins of meaning but revitalised fragments, stems cells of meaning ready-to-be-remade.A lineage of parodic works will be paraded and discussed that directly address the tacit relation of ground, horizon, orientation and position. This parody parade will form the basis of a critique and the analysis of the ontological orientations that for example, opposing systems of perspective insert as the very ground of meaning. The implication of this line of inquiry leads to the assertion that all descriptions of the world, universe and the cosmos are parodies in search of an origin. Totalised or unified images of the ground of meaning are already parodies of a/the set of conditions by which meaning operates that also produce a trajectory that as a lived-abstraction directs or hijacks subsequent productions of meaning