11 resultados para MSP

em Deakin Research Online - Australia


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Digital forensics isn't commonly a part of an undergraduate university degree, but Deakin University in Australia recently introduced the subject as part of an IT security course. As instructors, we've found that digital forensics complements our other security offerings because it affords insights into why and how security fails. A basic part of this course is an ethics agreement signed by students and submitted to the unit instructor. This agreement, approved by Deakin University's legal office and consistent with Barbara Endicott-Popovsky's approach, requires students to maintain a professional and ethical attitude to the subject matter and its applications. Assignments regularly cast students in the role of forensic professional. Our teaching team emphasizes throughout the course that professional conduct establishes credibility with employers and customers as well as colleagues, and is required to perform the job effectively. This article describes our experiences with this course.

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This chapter examines understandings of marriage among missionaries and humanitarians connected with two early colonial ‘Native Institutions’. A comparison of the Parramatta Native Institution in New South Wales and the Albany Native Institution in Western Australia demonstrates that concerns about marriage were central in discussions about the formation and maintenance of these Institutions. Both of these Institutions were established and supported by British evangelicals, who had brought with them to Australia powerful assumptions about gender roles, particularly in
marriage. These assumptions influenced their decisions regarding the children who resided in the Native Institutions. Within specific colonial contexts, however, the assumptions of humanitarians and missionaries did not remain static, and debates over the futures of the Aboriginal children they sought to educate reveal complex and shifting hierarchies of race, gender and class.

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A review of the literature established that localization acuity measured during monaural listening conditions was directly related to various methodological considerations. These included method of attenuation, segment of auditory space where monaural localization was measured, and the presence or absence of head movements. An extensive measurement of monaural localization was made with due consideration of these factors, allowing a more comprehensive evaluation of monaural acuity and the underlying processes that were involved. Establishing a monaural condition is dependent both on the attenuation level of the occluded ear and the signal level, both of which are clearly inter-related since the attenuation level of the occluded ear sets the maximum level of die stimulus. In a series of experiments it was established that there was a minimum signal level for accurate localization. Testing on both sides of the head revealed that there were three regions of monaural localization acuity. The first was about the interaural axis on the ipsilateral ear where monaural localization was relatively accurate, the second a region either side of the MSP where there was some loss of localization, and a third about the interaural axis on the ipsilateral side where virtually no monaural localization ability existed. In the final series of experiments it was established that head-movements allowed subjects to extend the accuracy of the first region by minimizing the distance between the sound and the ipsilateral interaural axis, thus compensating for the loss of localization ability in the second and third regions. This was determined from changes recorded in the error data, and also the extent and direction of measured head-movements. The results of this series of experiments demonstrated the relationship between spectral cues and monaural localization. Firstly, monaural localization was not possible in the absence of accurate spectral information. Thus large errors were observed in the third region where there was blockage of the high-frequencies by the head, and in all regions during the presentation of low signal levels where the high-frequencies fell below threshold. Secondly, the inaccuracy of the second region due to the loss of information from the second pinna suggested that there was a binaural component with relation to pinna cues. It seems that for sounds in this region the spectral modifications from both pinnae are processed to determine a sound's location in space.

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Antibodies capable of inhibiting the invasion of Plasmodium merozoites into erythrocytes are present in individuals that are clinically immune to the malaria parasite. Those targeting the 19-kD COOH-terminal domain of the major merozoite surface protein (MSP)-119 are a major component of this inhibitory activity. However, it has been difficult to assess the overall relevance of such antibodies to antiparasite immunity. Here we use an allelic replacement approach to generate a rodent malaria parasite (Plasmodium berghei) that expresses a human malaria (Plasmodium falciparum) form of MSP-119. We show that mice made semi-immune to this parasite line generate high levels of merozoite inhibitory antibodies that are specific for P. falciparum MSP-119. Importantly, protection from homologous blood stage challenge in these mice correlated with levels of P. falciparum MSP-119–specific inhibitory antibodies, but not with titres of total MSP-119–specific immunoglobulins. We conclude that merozoite inhibitory antibodies generated in response to infection can play a significant role in suppressing parasitemia in vivo. This study provides a strong impetus for the development of blood stage vaccines designed to generate invasion inhibitory antibodies and offers a new animal model to trial P. falciparum MSP-119 vaccines.

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CD1d-restricted NKT cells are a novel T cell lineage with unusual features. They co-express some NK cell receptors and recognize glycolipid antigens through an invariant T cell receptor (TCR) in the context of CD1d molecules. Upon activation through the TCR, NKT cells produce large amounts of IFN- and IL-4. It has been proposed that rapid cytokine output by activated NKT cells may induce bystander activation of other lymphoid lineages. The impact of CD1d-restricted NKT cell activation in the induction of B cell-mediated immune responses to infection is still unclear. We show here that CD1-restricted NKT cells contribute to malarial splenomegaly associated with expansion of the splenic B cell pool and enhance parasite-specific antibody formation in response to Plasmodium berghei infection. The increased B cell-mediated response correlates with the ability of NKT cells to promote Th2 immune responses. Additionally, antibody responses against the glycosylphosphatidylinositol (GPI)-anchored protein merozoite surface protein 1 (MSP-1) were found to be significantly lower in CD1-/- mice compared to wild-type animals. P. berghei-infected MHC class II (MHCII)-/- mice also generated antibodies against MSP-1, suggesting that antibody production against GPI-anchored antigens in response to malaria infection can arisefrom both MHCII-dependent and independent pathways.

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Purpose – The purpose of this paper is to highlight the importance and complexities of the knowledge transfer process in the provision of effective managed after-sales IT support, when the web is used for service delivery.

Design/methodology/approach – The paper features an interpretive case study of a multinational Managed Service Provider (MSP) and a focus group of representatives from five comparable MSPs.

Findings – The paper finds that MSPs that use web-based channels for the provision of after-sales IT support services need to address a range of important social and organisational issues in order to realise cost and efficiency-based benefits.

Research limitations/implications – The paper provides a four stage processual model of knowledge transfer in the provision of web-based managed after-sales IT support services. The barriers and enablers of knowledge transfer at each stage are identified. The paper adopts a MSP perspective and suggests that further research from the customer perspective is required.

Practical implications – The paper highlights some important social and organisational enablers and barriers, which will guide MSPs when providing managed after-sales IT support using webbased channels.

Originality/value – The paper provides the first staged model of inter-organisational knowledge transfer in a complex multi-organisational and multi-channel web-based context.

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An article [1] in the Journal of Forensic Accounting reviewed the background and development of forensic accounting using Benford’s Law (BL)—an interesting property in natural occurring numbers that can help identify fraudulent data in corporate financial records. The field of forensic accounting, and this law in particular, are relevant in light of several recent events that required the identification of false or otherwise misrepresented information in corporate financial statements. Such information was used or intended to be used to fraudulently misappropriate company funds, cover up illegal transactions, or evade taxation. In this article, we comment on forensic accounting and BL from a signal processing (SP) perspective.

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Data analysis using intelligent systems is a key solution to many industrial problems. In this paper, a mutation-based evolving artificial neural network, which is based on an integration of the Fuzzy ARTMAP (FAM) neural network and evolutionary programming (EP), is proposed. The proposed FAMEP model is applied to detect and classify possible faults from a number of sensory signals of a circulating water system in a power generation plant. The efficiency of FAM-EP is assessed and compared with that of the original FAM network in terms of classification accuracy as well as network complexity. In addition, the bootstrap method is used to quantify the performance statistically. The results positively demonstrate the usefulness of FAM-EP in tackling data classification problems.

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This paper presents the development of a keystroke dynamics-based user authentication system using the ARTMAP-FD neural network. The effectiveness of ARTMAPFD in classifying keystroke patterns is analyzed and compared against a number of widely used machine learning systems. The results show that ARTMAP-FD performs well against many of its counterparts in keystroke patterns classification. Apart from that, instead of using the conventional typing timing characteristics, the applicability of typing pressure to ascertaining user's identity is investigated. The experimental results show that combining both latency and pressure patterns can improve the Equal Error Rate (ERR) of the system.