12 resultados para Imaging techniques

em Deakin Research Online - Australia


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Despite Wheatstone’s academic interests in the device, the stereoscope languished somewhat as an optical toy. Yet the advent of 3D screen-spaces for home and mass entertainment suggests today’s consumers and practitioners of screen culture hold the view that screen culture will be ‘improved’ through 3D imaging technologies. Like cinema and photography, stereoscopic 3D imaging has the potential to transform visual culture. But what is transformed, as optics and electronic imaging techniques deliver Alice in Wonderland in 3D? This paper links the advent of 3D cinema and TV to the notion that vision is itself a ‘technology of the visual’. As such, our innate binocular stereoacuity is ripe for exploitation by developers of 3D imaging technologies. I argue that contemporary 3D imaging marks an epistemological visual-perceptual shift: toward screenspaces becoming spaces for potential action. Such a shift entails seeing as doing rather than seeing as thinking. 3D imaging exploits binocular vision’s spatial acuity (stereopsis), but is effective only for objects within near distal space. The 3D effect tapers off dramatically for objects only some metres away, because the two retinal images lack significant lateral disparity (difference) to trigger stereopsis: the imagery flattens out and becomes ‘monoscopic’. Information available from conventional 2D media entails a peculiarly unspecified spatiality. Perceptually, the contents of a conventional cinematic screen are like those of a painting: they are situated neither near nor far, and constitute a shared and ambiguous visual space. Our own eyes are like those of a cat: frontally placed for predatory action. The visuality of 3D screen-spaces assumes a perceptuality of the near-by and close at hand, since this is the structure of the visible information to which stereopsis is adapted to respond. Noting the binocular acuity of predatory animals, as well as some etymological links, this paper examines the implications of perceptually ‘capturing’ the sensation of visually solid objects in one’s immediate space. Stereopsis is about decisive action within an immediate environment: but it also presupposes the single viewpoint of an active observer toward which the 3D imagery is targeted.

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Aim
The purpose of this paper is to give an overview of the imaging techniques that are currently used to study the effects of exercise on bone architecture.

Current knowledge
It is now widely accepted that the prevention of osteoporosis must be initiated in childhood, because the immature skeleton is more responsive to physical loading. Exercise recommendations for bone health promotion must consider the effects of loading not only on the more traditional measures of bone mineral content and macroarchitecture, but also on the microarchitecture and structural properties of the skeleton. The latter requires high precision 3D methods like quantitative computed tomography and magnetic resonance imaging.

Prospects
Imaging resolutions used most commonly in exercise studies of children have sufficient precision to assess bone density and gross geometry. However, they remain insufficient to clearly depict and quantify the trabecular bone microarchitecture in vivo in humans.

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Background This study aimed to investigate the relationship between depressive and anxiety disorders and indices of adiposity, including body fat mass and percent body fat, as measured by dual energy X-ray absorptiometry.

Methods In this observational study of 979 randomly-selected women aged 20–93 years, psychiatric history was ascertained using a structured clinical interview (SCID-I/NP). Total body fat was assessed using dual-energy X-ray absorptiometry and weight, height and waist circumference were measured. Medication use and lifestyle factors were self-reported.

Results Those with a lifetime history of depression had increased fat mass (+ 7.4%) and percent body fat (+ 4.3%), as well as greater mean weight (+ 3.3%), waist circumference (+ 2.9%) and BMI (+ 3.5%) after adjustment for age, anxiety, alcohol consumption, physical activity and past smoking. Furthermore, those meeting criteria for a lifetime history of depression had a 1.7-fold increased odds of being overweight or obese (BMI ≥ 25), a 2.0-fold increased odds of being obese (BMI ≥ 30) and a 1.8-fold increased odds of having a waist circumference ≥ 80 cm. These patterns persisted after further adjustment for psychotropic medication use, smoking status and energy intake. No differences in any measures of adiposity were observed among those with anxiety disorders compared to controls.

Limitations
There is potential for unrecognised confounding, interpretations are limited to women and a temporal relationship could not be inferred.

Conclusions Depression was associated with greater adiposity. The difference in body fat mass was numerically greater than differences in indirect measures of adiposity, suggesting that the latter may underestimate the extent of adiposity in this population.

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Maintaining low body weight for the sake of performance and aesthetic purposes is a common feature among young girls and women who exercise on a regular basis, including elite, college and high-school athletes, members of fitness centres, and recreational exercisers. High energy expenditure without adequate compensation in energy intake leads to an energy deficiency, which may ultimately affect reproductive function and bone health. The combination of low energy availability, menstrual disturbances and low bone mineral density is referred to as the ‘female athlete triad’. Not all athletes seek medical assistance in response to the absence of menstruation for 3 or more months as some believe that long-term amenorrhoea is not harmful. Indeed, many women may not seek medical attention until they sustain a stress fracture.
This review investigates current issues, controversies and strategies in the clinical management of bone health concerns related to the female athlete triad. Current recommendations focus on either increasing energy intake or decreasing energy expenditure, as this approach remains the most efficient strategy to prevent further bone health complications. However, convincing the athlete to increase energy availability can be extremely challenging.
Oral contraceptive therapy seems to be a common strategy chosen by many physicians to address bone health issues in young women with amenorrhoea, although there is little evidence that this strategy improves bone mineral density in this population. Assessment of bone health itself is difficult due to the limitations of dual-energy X-ray absorptiometry (DXA) to estimate bone strength. Understanding how bone strength is affected by low energy availability, weight gain and resumption of menses requires further investigations using 3-dimensional bone imaging techniques in order to improve the clinical management of the female athlete triad.

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Magnetic Resonance Imaging (MRI) is one of the prominent medical imaging techniques. This process is time-consuming and can take several minutes to acquire one image. The aim of this research is to reduce the imaging process time of MRI. This issue is addressed by reducing the number of acquired measurements using theory of Compressive Sensing (CS). Compressive Sensing exploits sparsity in MR images. Randomly under sampled k-space generates incoherent noise which can be handled using a nonlinear image reconstruction method. In this paper, a new framework is presented based on the idea to exploit non-uniform nature of sparsity in MR images, where local sparsity constrains were used instead of traditional global constraint, to further reduce the sample set. Experimental results and comparison with CS using global constraint are demonstrated.

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Recognition algorithms that use data obtained by imaging faces in the thermal spectrum are promising in achieving invariance to extreme illumination changes that are often present in practice. In this paper we analyze the performance of a recently proposed face recognition algorithm that combines visual and thermal modalities by decision level fusion. We examine (i) the effects of the proposed data preprocessing in each domain, (ii) the contribution to improved recognition of different types of features, (iii) the importance of prescription glasses detection, in the context of both 1-to-N and 1-to-1 matching (recognition vs. verification performance). Finally, we discuss the significance of our results and, in particular, identify a number of limitations of the current state-of-the-art and propose promising directions for future research.

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Marine spatial planners and managers need timely and accurate maps describing biological communities at the seafloor. This thesis employs state of the art sonar equipment and seafloor imaging techniques to answer some fundamental questions about how these communities are distributed through space and time.

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The nano convergence is a historic event, similar to the advent of cyberspace, which has equal potential disruption. As well as the aesthetics of communication Mario Costa has a technological sublime mediated through imaging techniques, we propose in this work the emergence of an aesthetic of nanocomunicasio, which, in turn, proposes a nanotechnological sublime mediated through technological individuation. While the technological sublime Mario Costa is entirely based on the Kantian sublime, the sublime nanotechnology is inspired by the sublime transimanente Schopenhauer. If the technological sublime Mario Costa is connected to virtuality and reproducibility of digital imaging techniques, we have the sublime nanotechnology refers instead to the materiality and autorreprodutibilidade the principle of individuation.

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This paper presents the design and development of a low cost three-dimensional laser imaging system for scanning suitable surfaces. A generic, low cost, off-the-shelf laser range finder is used to obtain the primary one dimensional distance measurement. The range finder’s laser beam is reflected by a twin-axis mirror assembly driven by stepper motors providing the system with two angular degrees of freedom, allowing 3-D measurements to be determined. A camera and image processing techniques are used to determine the measured 1-D range value from the generic range-finding device. A computer program then uses the obtained data to create a 3-D point cloud. An algorithm is then used to construct a 3-D wire frame mesh representing the scanned surface. The system has an angular resolution of 1.8° and the results obtained demonstrate the system to have an accuracy of approximately ± 2cm at a scanning distance of 1.0m.

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Analytical q-ball imaging is widely used for reconstruction of orientation distribution function (ODF) using diffusion weighted MRI data. Estimating the spherical harmonic coefficients is a critical step in this method. Least squares (LS) is widely used for this purpose assuming the noise to be additive Gaussian. However, Rician noise is considered as a more appropriate model to describe noise in MR signal. Therefore, the current estimation techniques are valid only for high SNRs with Gaussian distribution approximating the Rician distribution. The aim of this study is to present an estimation approach considering the actual distribution of the data to provide reliable results particularly for the case of low SNR values. Maximum likelihood (ML) is investigated as a more effective estimation method. However, no closed form estimator is presented as the estimator becomes nonlinear for the noise assumption of the Rician distribution. Consequently, the results of LS estimator is used as an initial guess and the more refined answer is achieved using iterative numerical methods. According to the results, the ODFs reconstructed from low SNR data are in close agreement with ODFs reconstructed from high SNRs when Rician distribution is considered. Also, the error between the estimated and actual fiber orientations was compared using ML and LS estimator. In low SNRs, ML estimator achieves less error compared to the LS estimator.

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This is the first ever attempt to combine anti-cancer therapeutic effects of emerging anticancer biodrug bovine lactoferrin (bLf), and multimodal imaging efficacy of Fe3O4 nanoparticles (NPs) together, as a saturated Fe3O4-bLf. For cancer stem cell specific uptake of nanocapsules/nanocarriers (NCs), Fe3O4-bLf was encapsulated in alginate enclosed chitosan coated calcium phosphate (AEC-CP) NCs targeted (Tar) with locked nucleic acid (LNA) modified aptamers against epithelial cell adhesion molecule (EpCAM) and nucleolin markers. The nanoformulation was fed orally to mice injected with triple positive (EpCAM, CD133, CD44) sorted colon cancer stem cells in the xenograft cancer stem cell mice model. The complete regression of tumor was observed in 70% of mice fed on non-targeted (NT) NCs, with 30% mice showing tumor recurrence after 30 days, while only 10% mice fed with Tar NCs showed tumor recurrence indicating a significantly higher survival rate. From tumor tissue analyses of 35 apoptotic markers, 55 angiogenesis markers, 40 cytokines, 15 stem cell markers and gene expression studies of important signaling molecules, it was revealed that the anti-cancer mechanism of Fe3O4-bLf was intervened through TRAIL, Fas, Fas-associated protein with death domain (FADD) mediated phosphorylation of p53, to induce activation of second mitochondria-derived activator of caspases (SMAC)/DIABLO (inhibiting survivin) and mitochondrial depolarization leading to release of cytochrome C. Induction of apoptosis was observed by inhibition of the Akt pathway and activation of cytokines released from monocytes/macrophages and dendritic cells (interleukin (IL) 27, keratinocyte chemoattractant (KC)). On the other hand, the recurrence of tumor in AEC-CP-Fe3O4-bLf NCs fed mice mainly occurred due to activation of alternative pathways such as mitogen-activated protein kinases (MAPK)/extracellular signal-regulated kinases (ERK) and Wnt signaling leading to an increase in expression of survivin, survivin splice variant (survivin 2B) and other anti-apoptotic proteins Bad, Bcl-2 and XIAP. Apart from the promising anti-cancer efficacy and the exceptional tumor targeting ability observed by multimodal imaging using near-infrared (NIR) imaging, magnetic resonance imaging (MRI) and computerized tomographic (CT) techniques, these NCs also maintained the immunomodulatory benefits of bLf as they were able to increase the RBC, hemoglobin, iron calcium and zinc levels in mice.