Classification of healthcare data using genetic fuzzy logic system and wavelets

Healthcare plays an important role in promoting the general health and well-being of people around the world. The difficulty in healthcare data classification arises from the uncertainty and the high-dimensional nature of the medical data collected. This paper proposes an integration of fuzzy standard additive model (SAM) with genetic algorithm (GA), called GSAM, to deal with uncertainty and computational challenges. GSAM learning process comprises three continual steps: rule initialization by unsupervised learning using the adaptive vector quantization clustering, evolutionary rule optimization by GA and parameter tuning by the gradient descent supervised learning. Wavelet transformation is employed to extract discriminative features for high-dimensional datasets. GSAM becomes highly capable when deployed with small number of wavelet features as its computational burden is remarkably reduced. The proposed method is evaluated using two frequently-used medical datasets: the Wisconsin breast cancer and Cleveland heart disease from the UCI Repository for machine learning. Experiments are organized with a five-fold cross validation and performance of classification techniques are measured by a number of important metrics: accuracy, F-measure, mutual information and area under the receiver operating characteristic curve. Results demonstrate the superiority of the GSAM compared to other machine learning methods including probabilistic neural network, support vector machine, fuzzy ARTMAP, and adaptive neuro-fuzzy inference system. The proposed approach is thus helpful as a decision support system for medical practitioners in the healthcare practice.

Hierarchical gene selection and genetic fuzzy system for cancer microarray data classification

This paper introduces a novel approach to gene selection based on a substantial modification of analytic hierarchy process (AHP). The modified AHP systematically integrates outcomes of individual filter methods to select the most informative genes for microarray classification. Five individual ranking methods including t-test, entropy, receiver operating characteristic (ROC) curve, Wilcoxon and signal to noise ratio are employed to rank genes. These ranked genes are then considered as inputs for the modified AHP. Additionally, a method that uses fuzzy standard additive model (FSAM) for cancer classification based on genes selected by AHP is also proposed in this paper. Traditional FSAM learning is a hybrid process comprising unsupervised structure learning and supervised parameter tuning. Genetic algorithm (GA) is incorporated in-between unsupervised and supervised training to optimize the number of fuzzy rules. The integration of GA enables FSAM to deal with the high-dimensional-low-sample nature of microarray data and thus enhance the efficiency of the classification. Experiments are carried out on numerous microarray datasets. Results demonstrate the performance dominance of the AHP-based gene selection against the single ranking methods. Furthermore, the combination of AHP-FSAM shows a great accuracy in microarray data classification compared to various competing classifiers. The proposed approach therefore is useful for medical practitioners and clinicians as a decision support system that can be implemented in the real medical practice.

Human perception-based washout filtering using genetic algorithm

The Motion Cueing Algorithm (MCA) transforms longitudinal and rotational motions into simulator movement, aiming to regenerate high fidelity motion within the simulators physical limitations. Classical washout filters are widely used in commercial simulators because of their relative simplicity and reasonable performance. The main drawback of classical washout filters is the inappropriate empirical parameter tuning method that is based on trial-and-error, and is effected by programmers’ experience. This is the most important obstacle to exploiting the platform efficiently. Consequently, the conservative motion produces false cue motions. Lack of consideration for human perception error is another deficiency of classical washout filters and also there is difficulty in understanding the effect of classical washout filter parameters on generated motion cues. The aim of this study is to present an effortless optimization method for adjusting the classical MCA parameters, based on the Genetic Algorithm (GA) for a vehicle simulator in order to minimize human sensation error between the real and simulator driver while exploiting the platform within its physical limitations. The vestibular sensation error between the real and simulator driver as well as motion limitations have been taken into account during optimization. The proposed optimized MCA based on GA is implemented in MATLAB/Simulink. The results show the superiority of the proposed MCA as it improved the human sensation, maximized reference signal shape following and exploited the platform more efficiently within the motion constraints.

A new genetic algorithm based on modified Physarum network model for bandwidth-delay constrained least-cost multicast routing

A mobile ad hoc network is a kind of popular self-configuring network, in which multicast routing under the quality of service constraints, is a significant challenge. Many researchers have proved that such problem can be formulated as a NP-complete problem and proposed some swarm-based intelligent algorithms to solve the optimal solution, such as the genetic algorithm (GA), bees algorithm. However, a lower efficiency of local search ability and weak robustness still limit the computational effectiveness. Aiming to those shortcomings, a new hybrid algorithm inspired by the self-organization of Physarum, is proposed in this paper. In our algorithm, an updating scheme based on Physarum network model (PM) is used for improving the crossover operator of traditional GAs, in which the same parts of parent chromosomes are reserved and the new offspring by the PM is generated. In order to estimate the effectiveness of our proposed optimized scheme, some typical genetic algorithms and their updating algorithms (PMGAs) are compared for solving the multicast routing on four different datasets. The simulation experiments show that PMGAs are more efficient than original GAs. More importantly, the PMGAs are more robustness that is very important for solving the multicast routing problem. Moreover, a series of parameter analyses is used to find a set of better setting for realizing the maximal efficiency of our algorithm.