Comparing the hairiness of solospun and ring spun worsted yarns

This paper compares the hairiness of Solospun yarns with conventional ring spun worsted yams of the same specifications. A 24-spindles worsted ring spinning frame is used to spin the Solospun and conventional ring spun yarns at the same time, and yarn hairiness is measured. The total hairiness number (Tp), the number of hairs longer than or equal to 3mm (S3), the percentage of longer hairs in total hairs (100S3/Tp), and the total hair length per unit yarn length (K' ) are used to compare the hairiness of these yams. The results indicate that the Solospun yarn exhibits less hairiness in each of the hair length groups and has lower variations in yarn hairiness. The hair-length distribution of the Solospun yarn follows an exponential law just like conventional ring spun yams. There is a statistically significant difference between the Solospun and conventional ring spun yams for T p, S3, and K', but the difference in 1 00S 3/Tp is not statistically significant for these yams. In addition, the Tp, S3, and K' values of the Solospun yarn decrease with twist increase and increase with spindle speed increase, but the 100S3/Tp values of the Solospun and conventional ring spun yarns in this study behave differently in that they are affected by twist level and spindle speed.

A controlled experiment on yarn hairiness and fabric pilling

This study focused on the hairiness of worsted wool yarns and how it affects the pilling propensity of knitted wool fabrics. Conventional worsted ring spun yarns were compared with comparable SolospunTM yarns and yarns modified with a hairiness reducing air nozzle in the winding process (JetWind). Measurements of yarn hairiness (S3) on the Zweigle G565 hairiness meter showed a reduction in the S3 value of approximately 46% was achieved using SolospunTM ring spinning attachment and a 33% reduction was achieved using the JetWind process. Interestingly, subsequent evaluation of the pilling performance of fabrics made from the SolospunTM spun yarn and JetWind modified yarn showed a half grade and full grade improvement, respectively over a similar fabric made from conventional ring spun yarns. This result suggested that a relatively large reduction in yarn hairiness was needed to achieve a moderate improvement in fabric pilling, and that the nature of yarn hairiness was also a key factor in influencing fabric pilling propensity. It is postulated that the wrapping of surface hairs by the air vortex in the JetWind process may limit the ability of those surface fibers to form fuzz and reach the critical height required for pill formation.

The new solo-siro spun process for worsted yarns

The aim of this paper was to explore whether the properties of worsted yarns, especially hairiness, can be improved by combining the Solospun and Sirospun processes into a single Solo-Siro spun process. Wool fibres of 19 and 21 μm in average diameter were spun into 40 tex yarns at different twist levels, using the conventional ring, Sirospun and Solo-Siro spun systems, respectively. These yarns were then tested for a range of properties, including hairiness, tenacity, elongation and evenness, for comparison purposes. The statistical analysis results indicate that the hairiness (S3 value) of Solo-Siro spun yarns was significantly less than that of both Sirospun and normal ring spun yarns. In addition, the tenacity of the Solo-Siro spun yarns was higher than that of the normal ring spun yarns, while changes in yarn breaking elongation were not statistically significant. For the 21 μm wool, it was found that the evenness of Solo-Siro spun yarns deteriorated slightly in comparison with that of Sirospun and conventional ring spun yarns.

Sequential 123-I-iododexetimide scans in temporal lobe epilepsy: comparison with neuroimaging scans (MR imaging and 18-F-FDG-PET imaging)

Purpose Muscarinic acetylcholine receptors (mAChRs) play an important role in the generation of seizures. Single-photon emission computed tomography (SPECT) with ¹²³I-iododexetimide (IDEX) depicts tracer uptake by mAChRs. Our aims were to: (a) determine the optimum time for interictal IDEX SPECT imaging; (b) determine the accuracy of IDEX scans in the localisation of seizure foci when compared with video EEG and MR imaging in patients with temporal lobe epilepsy (TLE); (c) characterise the distribution of IDEX binding in the temporal lobes and (d) compare IDEX SPECT and ¹⁸F-fluorodeoxyglucose (FDG) positron emission tomography (PET) in identifying seizure foci.
Methods We performed sequential scans using IDEX SPECT imaging at 0, 3, 6 and 24 h in 12 consecutive patients with refractory TLE undergoing assessment for epilepsy surgery. Visual and region of interest analyses of the mesial, lateral and polar regions of the temporal lobes were used to compare IDEX SPECT, FDG PET and MR imaging in seizure onset localisation.
Results The 6-h IDEX scan (92%; κappa=0.83, p=0.003) was superior to the 0-h (36%; kappa=0.01, p>0.05), 3-h (55%;κappa=0.13, p>0.05) and 24-h IDEX scans in identifying the temporal lobe of seizure origin. The 6-h IDEX scan correctly predicted the temporal lobe of seizure origin in two patients who required intracranial EEG recordings to define the seizure onset. Reduced ligand binding was most marked at the temporal pole and mesial temporal structures. IDEX SPECT was superior to interictal FDG PET (75%; κappa=0.66, p=0.023) in seizure onset localisation. MR imaging was non-localising in two patients in whom it was normal and in another patient in whom there was bilateral symmetrical hippocampal atrophy.
Conclusion The 6-h IDEX SPECT scan is a viable alternative to FDG PET imaging in seizure onset localisation in TLE.

A morphology-related study on photodegradation of protein fibres

The wool fibre has a complex morphology, consisting of an outer layer of cuticle scales surrounding an inner cortex. These two components are hard to separate effectively except by using harsh chemical treatments, making it difficult to determine the susceptibility of the different components of the fibre to photoyellowing. An approach to this problem based on mechanical fibre modification is described. To expose the inner cortex of wool to different degrees, clean wool fibres were converted into ‘powders’ of various fineness via mechanical chopping, air-jet milling, ball milling or their combination. Four types of powdered wool (samples A, B, C and D) were produced with reducing particle size distributions and an increasing level of surface damage as observed using SEM. Sample A contained essentially intact short fibre snippets and sample D contained a large amount of exposed cortical materials. Samples B and C contained a mixture of short fibre snippets and cortical materials. Solid wool discs were then compressed from the corresponding powder samples in a polished stainless steel die to enable colour measurement and UV irradiation studies. ATR-FTIR studies on powder discs demonstrated a small shift in the amide I band from 1644 cm−1 for disc A to 1654 cm−1 for disc D due to the different structures of the wool cuticle and cortex, in agreement with previous studies. Similarly an increase in the intensity ratio of the amide I to amide II band (1540 cm−1) was observed for disc D, which contains a higher fraction of cortical material at the surface of the disc.

Discs prepared from sample D appeared the lightest in colour before exposure and had the slowest photoyellowing rate, whereas discs made from powders A–C with a higher level of cuticle coverage were more yellow before exposure and experienced a faster rate of photoyellowing. This suggests that the yellow chromophores of wool may be more prevalent in cuticle scales, and that wool photoyellowing occurs to a greater extent in the cuticle than in the cortex. Photo-induced chemiluminescence measurements showed that sample D had a higher chemiluminescence intensity after exposure to UVA radiation and a faster decay rate than samples A and B. Thus one of the roles of the wool cuticle may be to protect the cortex by quenching of free radical oxidation during exposure to the UV wavelengths present in sunlight.

Modeling of enzyme–substrate complexes for the metalloproteases MMP-3, ADAM-9 and ADAM-10

The matrix metalloproteases (MMPs) and the ADAMs (A Disintegrin And Metalloprotease domain) are proteolytic enzyme families containing a catalytic zinc ion, that are implicated in a variety of normal and pathological processes involving tissue remodeling and cancer. Synthetic MMP inhibitors have been designed for applications in pathological situations. However, a greater understanding of substrate binding and the catalytic mechanism is required so that more effective and selective inhibitors may be developed for both experimental and clinical purposes. By modeling a natural substrate spanning P4-P4‘ in complex with the catalytic domains, we aim to compare substrate-specificities between Stromelysin-1 (MMP-3), ADAM-9 and ADAM–10, with the aid of molecular dynamics simulations. Our results show that the substrate retains a favourable antiparallel beta-sheet conformation on the P-side in addition to the well-known orientation of the P'-region of the scissile bond, and that the primary substrate selectivity is dominated by the sidechains in the S1' pocket and the S2/S3 region. ADAM-9 has a hydrophobic residue as the central determinant in the S1' pocket, while ADAM-10 has an amphiphilic residue, which suggests a different primary specificity. The S2/S3 pocket is largely hydrophobic in all three enzymes. Inspired by our molecular dynamics calculations and supported by a large body of literature, we propose a novel, hypothetical, catalytic mechanism where the Zn-ion polarizes the oxygens from the catalytic glutamate to form a nucleophile, leading to a tetrahedral oxyanion anhydride transition state.

A particle swarm based hybrid system for imbalances medical data sampling

Background
Medical and biological data are commonly with small sample size, missing values, and most importantly, imbalanced class distribution. In this study we propose a particle swarm based hybrid system for remedying the class imbalance problem in medical and biological data mining. This hybrid system combines the particle swarm optimization (PSO) algorithm with multiple classifiers and evaluation metrics for evaluation fusion. Samples from the majority class are ranked using multiple objectives according to their merit in compensating the class imbalance, and then combined with the minority class to form a balanced dataset.

Results
One important finding of this study is that different classifiers and metrics often provide different evaluation results. Nevertheless, the proposed hybrid system demonstrates consistent improvements over several alternative methods with three different metrics. The sampling results also demonstrate good generalization on different types of classification algorithms, indicating the advantage of information fusion applied in the hybrid system.

Conclusion
The experimental results demonstrate that unlike many currently available methods which often perform unevenly with different datasets the proposed hybrid system has a better generalization property which alleviates the method-data dependency problem. From the biological perspective, the system provides indication for further investigation of the highly ranked samples, which may result in the discovery of new conditions or disease subtypes.

Effect of roller leveling on the bending behaviour of aged steel strip

The common grades of steel used in roll forming are: hot rolled carbon steel, high strength low alloy and recovery annealed cold rolled sheet. These steels are prone to ageing and are often skin passed and/or roller leveled to eliminate ageing as it can lead to problems in forming. In roll forming, shape defects such as bow, twist and camber are considered to be related to very small plastic strains in the longitudinal direction and hence knowledge of the material properties in the elastic plastic transition range is necessary if the process is to be modelled accurately. Previous studies with aluminium have indicated that skin pass rolling can lead to residual stresses in the strip. In this work, the study was extended to aged carbon steel and to the effect of roller leveling on both aged material and strip that had been given a light cold rolling to simulate a skin pass treatment. The results suggest that roller leveling reduced the magnitude of residual stresses resulting from skin pass rolling.

The significant differences observed between tensile and bending test results, at and near, the elastic plastic transition reinforces the need to consider bending properties when assessing the effect of prior processing on strip for roll forming.