Cell division protein ftsZ: running rings around bacteria, chloroplasts and mitochondria

Of all the proteins involved in prokaryotic cell division FtsZ is one of the earliest acting and most widely distributed, being found in all but a few species. We discuss several recent discoveries of FtsZ in eukaryotic cells and the protein’s role in the division of chloroplasts and mitochondria, organelles that are of bacterial origin.

Discourses of deception: cheating in professional running

Cheating, it is claimed, is anathema to sport. But is this the case? In this paper it is argued that cheating is integral to modern sport, that the model of sport as 'fair play' is simply an ideological guise of amateurism. The paper focuses on the sport of professional running which, since its origins in the eighteenth century, has been a gambling sport. Strategies involving cheating to manipulate wins, or losses, have featured in this sport as ways of increasing the probability of striking successful wagers. Such strategies are an accepted part of professional running: participants anticipate and expect others to be playing it in this way. However, a distinction is made between what is referred to in the paper as 'clean' cheating and 'dirty' cheating. The former is an accepted way of the sport, the latter occurs but is deprecated. The paper explores these different forms of cheating and the athletes' responses to them. Through a focus on the discourses of success in capitalist society, a model of cheating is developed to interpret such practices. Within the context of professional running, a working class sport, it is argued that, given the habitus of its practitioners, 'success' may be measured in terms of monetary gains and the 'kick-on' in life that these might provide. Cheating practices may serve to enhance the probability of success and social mobility. Given the relatively short career spans of sports people and the costs involved in developing the requisite skills, cheating may promote success and establish a financial base for post-sport careers. The paper concludes that cheating in sport can be anticipated as a feature of an acquisitive capitalist society.

`Just give me someone who can hit the ground running`: an investigation into the job-ready public relations graduate

Public relations educators perform an academic and vocational balancing act. Employers demand graduates with developed vocational skills. In the meantime, academics strive to provide students with work skills as well as solid theoretical base, and to also address emerging issues. This paper uses a case study in Geelong, Victoria to examine what Australian regional employers see as desirable attributes in public relations graduates. It then explores how educators address the needs of the employers as well as the needs of the public relations profession.

Games within games: gambling and trickery in professional running

Professional running is an overtly gambling sport in which a clear objective is to maximise winnings from the bookmakers, which is achieved through a careful concealment of a runner’s ability. Professional runners seldom win more than one significant race. Races are deliberately lost until runners acquire a sufficiently lenient handicap to significantly improve their chances of winning a race of their choosing. Successes, kudos and identities in this sport are evaluated from the cleverness of the win, largely measured by the trainer’s effectiveness in executing a gambling coup. The money prizes given to runners may be significantly bettered from gambling winnings and making the most of these is the major emphasis for most successful runners and trainers. Drawing from an ethnographic study of this sport in Australia, the paper argues that the gambling strategies of runners and trainers can be understood as zero-sum games.

Effect of carbohydrate ingestion on metabolism during running and cycling

The effects of carbohydrate or water ingestion on metabolism were investigated in seven male subjects during two running and two cycling trials lasting 60 min at individual lactate threshold using indirect calorimetry, U-¹⁴C-labeled tracer-derived measures of the rates of oxidation of plasma glucose, and direct determination of mixed muscle glycogen content from the vastus lateralis before and after exercise. Subjects ingested 8 ml/kg body mass of either a 6.4% carbohydrate-electrolyte solution (CHO) or water 10 min before exercise and an additional 2 ml/kg body mass of the same fluid after 20 and 40 min of exercise. Plasma glucose oxidation was greater with CHO than with water during both running (65 ± 20 vs. 42 ± 16 g/h; P < 0.01) and cycling (57 ± 16 vs. 35 ± 12 g/h; P < 0.01). Accordingly, the contribution from plasma glucose oxidation to total carbohydrate oxidation was greater during both running (33 ± 4 vs. 23 ± 3%; P < 0.01) and cycling (36 ± 5 vs. 22 ± 3%; P < 0.01) with CHO ingestion. However, muscle glycogen utilization was not reduced by the ingestion of CHO compared with water during either running (112 ± 32 vs. 141 ± 34 mmol/kg dry mass) or cycling (227 ± 36 vs. 216 ± 39 mmol/kg dry mass). We conclude that, compared with water, 1) the ingestion of carbohydrate during running and cycling enhanced the contribution of plasma glucose oxidation to total carbohydrate oxidation but 2) did not attenuate mixed muscle glycogen utilization during 1 h of continuous submaximal exercise at individual lactate threshold.

Energy system contribution during 200- to 1500-m running in highly trained athletes

Purpose: The purpose of the present study was to profile the aerobic and anaerobic energy system contribution during high-speed treadmill exercise that simulated 200-, 400-, 800-, and 1500-m track running events.

Methods: Twenty highly trained athletes (Australian National Standard) participated in the study, specializing in either the 200-m (N = 3), 400-m (N = 6), 800-m (N = 5), or 1500-m (N = 6) event (mean O₂ peak [mL·kg^-1·min^-1] ± SD = 56 ± 2, 59 ± 1, 67 ± 1, and 72 ± 2, respectively). The relative aerobic and anaerobic energy system contribution was calculated using the accumulated oxygen deficit (AOD) method.

Results: The relative contribution of the aerobic energy system to the 200-, 400-, 800-, and 1500-m events was 29 ± 4, 43 ± 1, 66 ± 2, and 84 ± 1% ± SD, respectively. The size of the AOD increased with event duration during the 200-, 400-, and 800-m events (30.4 ± 2.3, 41.3 ± 1.0, and 48.1 ± 4.5 mL·kg^-1, respectively), but no further increase was seen in the 1500-m event (47.1 ± 3.8 mL·kg^-1). The crossover to predominantly aerobic energy system supply occurred between 15 and 30 s for the 400-, 800-, and 1500-m events.

Conclusions: These results suggest that the relative contribution of the aerobic energy system during track running events is considerable and greater than traditionally thought.

Fenitrothion, an organophosphate, affects running endurance but not aerobic capacity in fat-tailed dunnarts (Sminthopsis crassicaudata)

We measured aerobic metabolism during cold exposure and exercise performance (run duration and oxygen consumption while running at 1 m s⁻¹) in the fat-tailed dunnart Sminthopsis crassicaudata, a dasyurid marsupial, before and after ingestion of 30 mg kg⁻¹ of fenitrothion, an organophosphate (OP) pesticide. Running endurance of OP-exposed animals was less than half that of control animals over the first 3 days after dosing and 55% of control animal endurance on day 5 post-dose. Despite these declines, peak metabolic rate at this running speed (9.3 times basal metabolic rate; BMR) was unaffected by OP exposure. Peak metabolic rate (PMR) and cumulative oxygen consumption during a 1-h exposure to conditions equivalent to −20 °C did not differ between OP-treated and control dunnarts, with PMR averaging 11 times BMR. We conclude that fenitrothion-induced exercise fatigue is not due to limitations in oxygen or substrate delivery to muscle or in their uptake per se, but more likely relates to decreased ability to sustain high-frequency neuromuscular function. The persistence of locomotor impairment following OP exposure in otherwise asymptomatic animals emphasizes the importance of using performance-based measures when characterising sublethal effects of pesticide exposure in an ecological context.

Slow component of VO2 during level and uphill treadmill running : relationship to aerobic fitness in endurance runners

The aim of this study was to compare the oxygen uptake (VO^sub 2^) slow component (SC) during level and uphill running in endurance runners, and to identify associations between the SC and the following aerobic fitness indicators: peak VO^sub 2^, running speed associated with the peak VO^sub 2^ (Vpeak), running speed at the lactic threshold and the VO^sub 2^ fraction elicited at the lactic threshold. Fourteen male endurance-trained runners underwent several 6-min bouts of level (LTR) and 10.5% uphill treadmill running. VO^sub 2^ SC was calculated as the difference between mean VO^sub 2^ during the 6th and the 3rd minutes. The highest mean values for the SC were 181.9±240.2 mL*min^sup -1^ for level running at ~94% peak VO^sub 2^ and 105.4±154.6 mL*min^sup -1^ for uphill running at ~90% peak VO^sub 2^. The SC observed during the last bout of the LTR correlated with peak VO^sub 2^ and with Vpeak (-0.71 and -0.76, P<0.05, respectively). The results show that for endurance-trained runners the magnitude of the SC is not affected by the treadmill gradient and that within a homogeneous sample of endurance-trained runners the SC does not correlate with indicators of aerobic fitness.

The running lie

The thesis consists of a novel entitled, The Running Lie, and an exegesis of 10,000 words. The novel is based on themes of maturation and homosexuality.

Running

Walk down a lane continuously. The film tries to destroy time by the cyclical reworking of a short period of time. Gradually the image becomes less discernible and the flashing positive and negative images force the viewer to stare rather than looking at the film. As the film progresses the viewer becomes trapped in a short period of time.