80 resultados para REJECTION


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New media epistemologies are emerging and might be considered illegitimate not because of plain rejection or criticism, but because of their alien origins and inter/ transdisciplinary implications. This article tells the story of a nano, tiny world within the world of media studies: the world of the term ‘nanomedia’ and its hyphenated sister ‘nano-media’. It narrates the different uses of this term as an illustration of the way in which disciplinarity determines the level of legitimacy or illegitimacy of an emerging term. We present another possible use of the term nanomedia in the field of media studies, one that is more closely aligned with its scientific origins. The importance and relevance of this proposition is connected to the present challenges we face in the anthropocene.

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This article builds on previous reception research and scholarship on makeover TV through an analysis of obese people's views of The Biggest Loser (TBL). TBL involves obese people competing to lose weight as personal trainers push them through dietary and physical activity regimes. We articulate four themes characterizing responses to TBL: “That's not reality,” “Public ownership and judgment of the fat body,” “The lure of the transformation,” and “A guilty pleasure.” We consider how these themes are reflected in participants' movement between mediated, discursive, transparent, and referential modes of reception. While some were adamant in their rejection of the program, others were ambivalent in accepting and identifying with the desire for weight loss but questioning TBL's aesthetic dimensions and moralizing undertones. We argue that the reflexivity of viewers complicates appraisals of TBL as governing at a distance and offer some alternative readings of the impact and appeal of the program.

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Nanoporous titania nanoparticles (NTNs) were synthesized and used as an additive at a low concentration of 0.1-1 wt % in the fabrication of poly(ethersulfone) (PES) ultrafiltration membranes via non-solvent-induced phase separation. The structure and properties of nanoparticles were characterized using nitrogen sorption, X-ray diffraction, scanning electron microscopy, and transmission electron microscopy. The NTNs have a size distribution with a particle size of mainly <100 nm and have a Brunauer, Emmett, and Teller surface area of ∼100 m2 g-1. The modified membranes were fabricated and investigated in terms of their pure water flux, solute rejection, and fouling resistance. The water permeability and molecular weight cutoffs (MWCOs) of membranes were determined under constant-pressure filtration in dead-end mode at 100 kPa. The membrane fouling resistance was characterized under constant flux operation using bovine serum albumin as a model foulant. The membranes were characterized in terms of morphology, porosity, pore size distribution, energy-dispersive X-ray spectroscopy, contact angle goniometry, surface free energy, and viscosity of the dope solution. Overall, the modified membrane showed increased wettability and reduced surface free energy and pore size. The modified UF membrane with 0.5 wt % NTN loading exhibited improved fouling resistance (fouling rate of 0.58 kPa/min compared to a rate of 0.70 kPa/min for the control membrane) with ∼80% water flux recovery. The same membrane showed an ∼20% increase in water flux, an improvement in MWCO, and a narrower pore size distribution.

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Medication adherence in kidney transplantation is critical to prevent graft rejection. Testing interventions designed to support patients to take their prescribed medications following a kidney transplant require an accurate measure of medication adherence. In research, the available methods for measuring medication adherence include self-report, pill counts, prescription refill records, surrogate measures of medication adherence and medication bottles with a microchip-embedded cap to record bottle openings. Medication bottles with a microchip-embedded cap are currently regarded as the gold standard measure. This commentary outlines the challenges in measuring medication adherence using electronic medication monitoring of kidney transplant patients recruited from five sites. The challenges included obtaining unanimous stakeholder support for using this method, agreement on an index medication to measure, adequate preparation of the patient and training of pharmacy staff, and how to analyze data when periods of time were not recorded using the electronic adherence measure. Provision of this information will enable hospital and community pharmacists to implement approaches that promote the effective use of this adherence measure for optimal patient outcomes.

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Cocaine dependence frequently co-occurs with personality disorders, leading to increased interpersonal problems and greater burden of disease. Personality disorders are characterised by patterns of thinking and feeling that divert from social expectations. However, the comorbidity between cocaine dependence and personality disorders has not been substantiated by measures of brain activation during social decision-making. We applied functional magnetic resonance imaging to compare brain activations evoked by a social decision-making task-the Ultimatum Game-in 24 cocaine dependents with personality disorders (CDPD), 19 cocaine dependents without comorbidities and 19 healthy controls. In the Ultimatum Game participants had to accept or reject bids made by another player to split monetary stakes. Offers varied in fairness (in fair offers the proposer shares ~50 percent of the money; in unfair offers the proposer shares <30 percent of the money), and participants were told that if they accept both players get the money, and if they reject both players lose it. We contrasted brain activations during unfair versus fair offers and accept versus reject choices. During evaluation of unfair offers CDPD displayed lower activation in the insula and the anterior cingulate cortex and higher activation in the lateral orbitofrontal cortex and superior frontal and temporal gyri. Frontal activations negatively correlated with emotion recognition. During rejection of offers CDPD displayed lower activation in the anterior cingulate cortex, striatum and midbrain. Dual diagnosis is linked to hypo-activation of the insula and anterior cingulate cortex and hyper-activation of frontal-temporal regions during social decision-making, which associates with poorer emotion recognition.