Fatty acid-benzendiol derivatives and methods of making and using thereof

Disclosed are compounds comprising a benzenediol derivative bound to one or more fatty acids. Also disclosed are nutritional supplements, pharmaceutical formulations, delivery devices, and foodstuffs comprising the disclosed compounds. Methods of using the disclosed compounds and compositions to improve health are also disclosed.

Anti-diabetic or anti-hypertensive dietary supplement

An anti-diabetic or anti-hypertensive fish protein hydrolysate is provided, in which the fish is of the genus Salmo or Oncorhynchus, and wherein the fish protein is hydrolysed by a metalloendopeptidase obtainable from Bacillus amyloliquefaciens. Methods of making and methods for using such fish protein hydrolysates are also provided.

Chromium-fatty acid compounds and methods of making and using thereof

Disclosed are compounds comprising one or more chromium atoms bonded to one or more fatty acids. Also disclosed are nutritional supplements, pharmaceutical formulations, delivery devices, and foodstuffs comprising the disclosed compounds. Methods of using the disclosed compounds and compositions to improve health are also disclosed

The importance of particle size in porous titanium and nonporous counterparts for surface energy and its impact on apatite formation

The importance of particle size in titanium (Ti) fabricated by powder metallurgy for the surface energy and its impact on the apatite formation was investigated. Four sorts of Ti powders of different mean particle size were realized through 20 min, 2 h, 5 h and 8 h of ball milling, respectively. Each sort of Ti powder was used to fabricate porous Ti and its nonporous counterparts sharing similar surface morphology, grain size and chemical composition, and then alkali-heat treatment was conducted on them. Surface energy was measured on the surfaces of the nonporous Ti counterparts due to the difficulty in measuring the porous surfaces directly. The surface energy increase on the alkali-heat-treated porous and nonporous Ti was observed due to the decrease in the particle size of the Ti powders and the presence of Ti–OH groups brought by the alkali-heat treatment. The apatite-inducing ability of the alkali-heat-treated porous and nonporous Ti with different surface energy values was evaluated in modified simulated body fluid and results indicated that there was a strong correlation between the apatite-inducing ability and the surface energy. The alkali-heat-treated porous and nonporous Ti discs prepared from the powders with an average particle size of 5.89 ± 0.76 μm possessed the highest surface energy and the best apatite-inducing ability when compared to the samples produced from the powders with the average particle size varying from 19.79 ± 0.31 to 10.25 ± 0.39 μm.

Solid state actuators based on polypyrrole and polymer-in-ionic liquid electrolytes

Novel polymer-in-ionic liquid electrolytes (PILEs) have been developed for solid state electrochemical actuators based on polypyrrole. The active polymer electrodes are readily oxidized/reduced without degradation in the PILE. It was found that the actuator cycle life is significantly enhanced in the PILE as is the ‘shelf life’ of the device.

Size based separation of microparticles using a dielectrophoretic activated system

This work describes the separation of polystyrene microparticles suspended in deionized (DI) water according to their dimensions using a dielectrophoretic (DEP) system. The DEP system utilizes curved microelectrodes integrated into a microfluidic system. Microparticles of 1, 6, and 15 μm are applied to the system and their response to the DEP field is studied at different frequencies of 100, 200, and 20 MHz. The microelectrodes act as a DEP barrier for 15 μm particles and retain them at all frequencies whereas the response of 1 and 6 μm particles depend strongly on the applied frequency. At 100 kHz, both particles are trapped by the microelectrodes. However, at 200 kHz, the 1 μm particles are trapped by the microelectrodes while the 6 μm particles are pushed toward the sidewalls. Finally, at 20 MHz, both particles are pushed toward the sidewalls. The experiments show the tunable performance of the system to sort the microparticles of various dimensions in microfluidic systems.

‘Inspired and assisted’, or ‘berated and destroyed’? Research leadership, management and performativity in troubled times

Research leadership in Australian universities takes place against a backdrop of policy reforms concerned with measurement and comparison of institutional research performance. In particular, the Excellence in Research in Australian initiative undertaken by the Australian Research Council sets out to evaluate research quality in Australian universities, using a combination of expert review process, and assessment of performance against ‘quality indicators’. Benchmarking exercises of this sort continue to shape institutional policy and practice, with inevitable effects on the ways in which research leadership, mentoring and practice are played out within university faculties and departments. In an exploratory study that interviewed 32 Australian academics in universities in four Australian states, we asked participants, occupying formal or informal research leadership roles, to comment on their perceptions of research leadership as envisioned and enacted in their particular workplaces. We found a pervasive concern amongst participants that coalesced around binaries characterized in metaphoric terms of ‘carrots and whips’. Research leadership was seen by many as managerial in nature, and as such, largely tethered to instrumentalist notions of productivity and performativity, while research cultures were seen as languishing under the demoralizing weight of reward and punishment systems. Here, we consider what is at stake for the future of the academic workforce under such conditions, arguing that new models of visionary research leadership are urgently needed in the ‘troubled times’ of techno-bureaucratic university reforms.

Exergy applied to lunar base design

This paper explores design considerations for energy efficiency in lunar habitats. It considers several previous lunar energy studies in regards to energy types and stages of energy requirements. If we are to obtain true sustainability in energy processes, we will need to design according to the principles “exergy”, considering both the first and the second laws of thermodynamics in a holistic and thorough evaluation of energy capture, transformation, and use. Such an evaluation will ascertain the source of energy, its processing and energy potential stages, as well as the task required. Traditional designs of facility thermal systems are frequently extremely wasteful: they dramatically increase both first costs and operating costs because they treat heating and cooling systems as separate entities, instead of an integrated energy system. Energy processes, the state of energy required to do a particular task, the embodied energy to complete or manufacture an object, and the wasted energy released are all important to conservation and obtaining an efficient and effective use (quality) of energy. If the regulation of energy processes is a concern in terrestrial habitation, it should be even more so for extra-terrestrial habitation where there is little margin for waste of any sort.

A Deweyan education as a spiritually creative enterprise

John Dewey was very much against dividing the spiritual from the material and claimed that both are present in action, typically through the notion of ends-in-view. He argued that genuinely creative actions require individuals with “significant conscious desires”. However this sort of creativity does not often occur due to our “intellectual laziness” which detracts us from making the effort to truly uncover ultimate and significant desires in our lives. It will be argued in this paper that the creativity promoted through a Deweyan education encourages individuals to face their fear of inner freedom and actively inquire into the spiritual dimension of life which is existential rather than idealistic. The case will be made that educated persons should be enabled, through experience, to actively and freely inquire into ends-in-view, including the ultimate and significant issues regarding the meaning and purpose of life.

Aiming for world peace by promoting 'violence' in education

In order to contribute towards UNESCO’s goal of pursuing world peace, aims of education must transcend the limited scope of national self-interest which has dominated schooling systems in the West for the last two centuries and further back when the survival of each polis in Ancient Greece was of paramount importance. Aims must therefore become different and the environment that is thought best for this to occur is a democratic one. The case is made that such a democratic environment should involve opportunities to evaluate the value of current aims of education and to explore others in light of the pressing need to pursue peace on a global scale. In order to promote such a democratic environment of discussion and debate the notion of ‘violence’ is considered as a potential framework for such a re-evaluation. The sort of ‘violence’ that is called for is in reference to its use by Emmanual Levinas who employed it emotively to misinterpret Kierkegaard. The use of this misapplied term ‘violence’ may nevertheless be of use in initiating the sort of inquiry of a Deweyean type regarded here to be necessary to improve aims of education democratically in order to pursue world peace.

Being philosophical regarding the evidence of 'what works'.

In this paper I am arguing that the debate regarding ‘what works’ in education practice should become more philosophical. By becoming more philosophical professional educators will be enabled to further recognise how unscientific and undemocratic the research which claims to represent ‘what works’ currently is by understanding more clearly the nature of its ‘evidence-base’ and its relation to education. This paper is structured into three parts. The first will address the philosophical aspect which is intrinsic to the discourse of education itself. The second section will offer a differentiation between empiricism and science which is important if we are to recognise the limitations of empirical ‘evidence’ regarding ‘what works’. The third and final section will draw upon Biesta’s notion of the ‘democratic deficit’ to make the case that if the evidence regarding ‘what works’ is only empirical rather than scientific then it is not the sort of evidence appropriate to the discourse of education.

Dewey's democracy as the kingdom of God on earth

John Dewey has been portrayed as a sort of villain in Rosenow's (1997) article which appeared in this journal, apparently because he was unfairly opposed to God and to religion, and also because he deliberately usurped religious language to ‘camouflage’ his secular ideas. By drawing mainly upon similar sources but with some important additions, I wish to challenge the four major concerns raised in Rosenow's article and in doing so aim to offer an alternative interpretation. It is understood here that Dewey's approach to religion was not so much religious as it was ‘spiritual’ and while developing and changing throughout his writings, his ideas on spirituality nevertheless were thoroughly entwined with his other views, especially those dealing with education, science and democracy.

An automatic application signature construction system for unknown traffic

Identifying applications and classifying network traffic flows according to their source applications are critical for a broad range of network activities. Such a decision can be based on packet header fields, packet payload content, statistical characteristics of traffic and communication patterns of network hosts. However, most present techniques rely on some sort of apriori knowledge, which means they require labor-intensive preprocessing before running and cannot deal with previously unknown applications. In this paper, we propose a traffic classification system based on application signatures, with a novel approach to fully automate the process of deriving signatures from unidentified traffic. The key idea is to integrate statistics-based flow clustering with payload-based signature matching method, so as to eliminate the requirement of pre-labeled training data sets. We evaluate the efficiency of our approach using real-world traffic trace, and the results indicate that signature classifiers built from clustered data and pre-labeled data are able to achieve similar high accuracy better than 99%.