A distributed active defense system against DDoS attacks

This thesis proposes a novel architecture of Distributed Active Defense System (DADS) against Distibuted Denial of Service (DDoS) attacks. Three sub-systems of DADS were built. For each sub-system corresponding algorithms were developed, prototypes implemented, criteria for evaluation were set up and experiments in both simulation and real network laboratory environments were carried out.

Managing realtime information flow between distributed discrete event simulation models

Investigates the creation of a method for the connection and communication of commercial off the shelf discrete-event simulation packages for simulation models of manufacturing systems. Through this research a method to connect different commercial off the shelf discrete-event simulation packages was successfully developed facilitating parallel development of models and the creation of extremely large models.

Co-ordination in multi-agent systems

A multi-agent system is a complex software system which is composed of many relative autonomous smaller softwares called agents. The research on multi-agent systems is concerned with the interaction and coordination among these agents to let them help each other to solve complicated problems, such as finance investment management. The principal contributions represented by these 50 selected papers are "cooperation under uncertainty in distributed expert systems (DESs)", "a tool and algorithms to build DESs", and "information gathering and decision making in multi-agent systems (MASs)".

Peak to average power ratio analysis for LTE systems

The 3rd generation partnership project (3GPP) long term evolution (LTE) standard uses single carrier frequency division multiple access (SCFDMA) scheme for the uplink transmissions and orthogonal frequency division multiplexing access (OFDMA) in downlink. SCFDMA uses DFT spreading prior to OFDMA modulation to map the signal from each user to a subset of the available subcarriers i.e., single carrier modulation. The efficiency of a power amplifier is determined by the peak to average power ratio (PAPR) of the modulated signal. In this paper, we analyze the PAPR in 3GPP LTE systems using root raised cosine based filter. Simulation results show that the SCFDMA subcarrier mapping has a significantly lower PAPR compared to OFDMA. Also comparing the three forms of SCFDMA subcarrier mapping, results show that interleave FDMA (IFDMA) subcarrier mapping with proposed root raised cosine filter reduced PAPR significantly than localized FDMA (LFDMA) and distributed (DFDMA) mapping. This improves its radio frequency (RF) power amplifier efficiency and also the mean power output from a battery driven mobile terminal.

A generic framework for three-factor authentication : preserving security and privacy in distributed systems

As part of the security within distributed systems, various services and resources need protection from unauthorized use. Remote authentication is the most commonly used method to determine the identity of a remote client. This paper investigates a systematic approach for authenticating clients by three factors, namely password, smart card, and biometrics. A generic and secure framework is proposed to upgrade two-factor authentication to three-factor authentication. The conversion not only significantly improves the information assurance at low cost but also protects client privacy in distributed systems. In addition, our framework retains several practice-friendly properties of the underlying two-factor authentication, which we believe is of independent interest.

Network management in distributed systems

Applications of localized surface plasmon resonance (LSPR) such as surface enhanced Raman scattering (SERS) devices, biosensors, and nano-optics are growing. Investigating and understanding of the parameters that affect the LSPR spectrum is important for the design and fabrication of LSPR devices. This paper studies different parameters, including geometrical structures and light attributes, which affect the LSPR spectrum properties such as plasmon wavelength and enhancement factor. The paper also proposes a number of rules that should be considered in the design and fabrication of LSPR devices.

A performance model of speculative prefetching in distributed information systems

Previous studies in speculative prefetching focus on building and evaluating access models for the purpose of access prediction. This paper investigates a complementary area which has been largely ignored, that of performance modelling. We use improvement in access time as the performance metric, for which we derive a formula in terms of resource parameters (time available and time required for prefetching) and speculative parameters (probabilities for next access). The performance maximization problem is expressed as a stretch knapsack problem. We develop an algorithm to maximize the improvement in access time by solving the stretch knapsack problem, using theoretically proven apparatus to reduce the search space. Integration between speculative prefetching and caching is also investigated, albeit under the assumption of equal item sizes.

Effect of speculative prefetching on network load in distributed systems

Previous studies in speculative prefetching focus on building and evaluating access models for the purpose of access prediction. This paper on the other hand investigates the performance of speculative prefetching. When prefetching is performed speculatively, there is bound to be an increase in the network load. Furthermore, the prefetched items must compete for space with existing cache occupants. These two factors-increased load and eviction of potentially useful cache entries-are considered in the analysis. We obtain the following conclusion: to maximise the improvement in access time, prefetch exclusively all items with access probabilities exceeding a certain threshold.

Randomised controlled trials and 'unexpected' adverse events associated with newly released drugs : improvements in pharmacovigilance systems are necessary for real-time identification of patient safety risks

Adverse drug events are one of the major causes of morbidity in developed countries, yet the drugs involved in these events have been trialled and approved on the basis of randomised controlled trials (RCTs), regarded as the study design that will produce the best evidence.

Though the focus on adverse drug events has been primarily on processes and outcomes associated with the use of these approved drugs, attention needs to be directed to the way in which the RCT study design is structured. The implementation of controls to achieve internal validity in RCTs may be the very controls that reduce external validity, and contribute to the levels of adverse drug events associated with the release of a new drug to the wider patient population.

An examination of these controls, and the effects they can have on patient safety, underscore the importance of knowing about how the clinical trials of a drug are undertaken, rather than relying only on the recorded outcomes.

As the majority of new drugs are likely to be prescribed to older patients who have one or more comorbidities in addition to that targeted by a new drug, and as the RCTs of those drugs typically under-represent the elderly and exclude patients with multiple comorbidities, timely assessment of drug safety signals is essential.

It is unlikely that regulatory jurisdictions will undertake a reassessment of safety issues for drugs that are already approved. Instead, reliance has been placed on adverse drug event reporting systems. Such systems have a very low reporting rate, and most adverse drug events remain unreported, to the eventual cost to patients and healthcare systems.

This makes it essential for near real-time systems that can pick up safety signals as they occur, so that modifications to the product information (or removal of the drug) can be implemented.

Can social dancing prevent falls in older adults? a protocol of the Dance, Aging, Cognition,Economics (DAnCE) fall prevention randomised controlled trial

Background:  Falls are one of the most common health problems among older people and pose a major economic burden on health care systems. Exercise is an accepted stand-alone fall prevention strategy particularly if it is balance training or regular participation in Tai chi. Dance shares the ‘holistic’ approach of practices such as Tai chi. It is a complex sensorimotor rhythmic activity integrating multiple physical, cognitive and social elements. Small-scale randomised controlled trials have indicated that diverse dance styles can improve measures of balance and mobility in older people, but none of these studies has examined the effect of dance on falls or cognition. This study aims to determine whether participation in social dancing: i) reduces the number of falls; and ii) improves cognitive functions associated with fall risk in older people.

Methods/design: A single-blind, cluster randomised controlled trial of 12 months duration will be conducted. Approximately 450 participants will be recruited from 24 self-care retirement villages that house at least 60 residents each in Sydney, Australia. Village residents without cognitive impairment and obtain medical clearance will be eligible. After comprehensive baseline measurements including physiological and cognitive tests and self-completed questionnaires, villages will be randomised to intervention sites (ballroom or folk dance) or to a wait-listed control using a computer randomisation method that minimises imbalances between villages based on two baseline fall risk measures. Main outcome measures are falls, prospectively measured, and the Trail Making cognitive function test. Cost-effectiveness and cost-utility analyses will be performed.

Discussion: This study offers a novel approach to balance training for older people. As a community-based approach to fall prevention, dance offers older people an opportunity for greater social engagement, thereby making a major contribution to healthy ageing. Providing diversity in exercise programs targeting seniors recognises the heterogeneity of multicultural populations and may further increase the number of taking part in exercise.

A potential-controlled switch on/off mechanism for selective excitation in mixed electrochemiluminescent systems

We demonstrate the complete, rapid, and reversible switching between the emissions from two electrogenerated chemiluminescence (ECL) systems contained within the same solution, controlled by simple modification of the applied potential. The fundamental bases of the approach are the ability to selectively 'switch on' luminophores at distinct oxidation potentials, and an intriguing observation that the emission from the well-known electrochemiluminescent complex, fac-Ir(ppy)3, (where ppy is 2-phenylpyridinato), can be selectively 'switched-off' at high overpotentials. The dependence of this phenomenon on high concentrations of the co-reactant implicates quenching of the excited [Ir(ppy)3]* state by electron transfer. Rapid spectral scanning during modulation of the applied potential reveals well resolved maxima for mixtures comprising either green and red or green and blue luminophores, illustrating the vast potential of this approach for multiplexed ECL detection.