Influence of stocking rate and mixed grazing of Angora goats and Merino sheep on animal and pasture production in southern Australia : 3 : mohair and wool production and quality

The effects of animal species (AS; Angora goats, Merino sheep, mixed-grazed goats and sheep at the ratio of 1:1) and stocking rate (SR; 7.5, 10 and 12.5 animals/ha) on fibre production and quality were determined in a replicated experiment on improved annual temperate pastures in southern Australia from 1981 to 1984. Separately grazed sheep produced the most total clean fibre/ha at each SR. Mixed-grazed treatments produced amounts of clean fibre/ha similar to the arithmetic mean of sheep and goat treatments at 7.5/ha (21.9 versus 21.3 kg/ha), 10% more at 10/ha (28.3 versus 25.3 kg/ha, P < 0.05) and 7% more at 12.5/ha (31.6 versus 29.6 kg/ha, P < 0.10). Clean wool production/head was affected by AS and SR but not year. Clean mohair production was affected by SR and year but not AS. Variation in mean fibre diameter (MFD) accounted for 67 and 71%, respectively, of the variation in clean wool and clean mohair production/head. There was an AS SR interaction for clean fibre production/t pasture. Growth rate of mohair was highest in autumn and least in summer. In each season, an increase in the SR reduced the clean mohair growth rate. Growth rate of wool was highest in spring and least in summer. Wool and mohair MFD were affected by an AS SR interaction. Mohair MFD was also affected by year and season. At 10/ha, wool from mixed-grazed sheep had a greater MFD than wool from separately grazed sheep (20.2 versus 18.9 μm) and mixed-grazed goats grew mohair 1 μm coarser than separately grazed goats. At 12.5/ha mixed-grazed goats grew mohair 1.9 μm finer than separately grazed goats. Mohair MFD was predicted by a multiple regression that included average liveweight for the period of fleece growth, season of growth (summer 1 μm finer than winter) and year (range 1.27 μm). Mohair MFD increased 4.7 μm/10 kg increase in average fleece-free liveweight (P = 6.4 10-14). Fleece-free liveweight alone accounted for 76.4% of the variation in mohair MFD. There was an AS SR interaction for the incidence of kemp and medullated fibres; under severe grazing pressure their incidence was suppressed. This experiment indicated that the principles associated with the effects of SR on wool production on annual temperate pastures apply to mohair production. Mixed grazing of Merino sheep and Angora goats produced complementary and competitive effects depending on the SR. Angora goats should not be grazed alone or mixed-grazed with sheep on annual temperate pastures at SR greater than that recommended for Merino sheep.

Animal migration : linking models and data beyond taxonomic limits

An international workshop on animal migration was held at the Lorentz Center in Leiden, The Netherlands, 2–6 March 2009, bringing together leading theoreticians and empiricists from the major migratory taxa, aiming at the identification of cutting-edge questions in migration research that cross taxonomic borders.

A role for glutathione in the pathophysiology of bipolar disorder and schizophrenia? Animal models and relevance to clinical practice.

The tripeptide, glutathione (glutamylcysteinylglycine) is the primary endogenous free radical scavenger in the human body. When glutathione (GSH) levels are reduced there is an increased potential for cellular oxidative stress, characterised by an increase and accruement of reactive oxygen species (ROS). Oxidative stress has been implicated in the pathology of schizophrenia and bipolar disorder. This could partly be caused by alterations in dopaminergic and glutamatergic activity that are implicated in these illnesses. Glutamate and dopamine are highly redox reactive molecules and produce ROS during normal neurotransmission. Alterations to these neurotransmitter pathways may therefore increase the oxidative burden in the brain. Furthermore, mitochondrial dysfunction, as a source of oxidative stress, has been documented in both schizophrenia and bipolar disorder. The combination of altered neurotransmission and this mitochondrial dysfunction leading to oxidative damage may ultimately contribute to illness symptoms. Animal models have been established to investigate the involvement of glutathione depletion in aspects of schizophrenia and bipolar disorder to further characterise the role of oxidative stress in psychopathology. Stemming from preclinical evidence, clinical studies have recently shown antioxidant precursor treatment to be effective in schizophrenia and bipolar disorder, providing a novel clinical angle to augment often suboptimal conventional treatments.