Initial medication adherence-review and recommendations for good practices in outcomes research: an ISPOR medication adherence and persistence special interest group report

Background: Positive associations between medication adherence and beneficial outcomes primarily come from studying filling/consumption behaviors after therapy initiation. Few studies have focused on what happens before initiation, the point from prescribing to dispensing of an initial prescription. Objective: Our objective was to provide guidance and encourage high-quality research on the relationship between beneficial outcomes and initial medication adherence (IMA), the rate initially prescribed medication is dispensed. Methods: Using generic adherence terms, an international research panel identified IMA publications from 1966 to 2014. Their data sources were classified as to whether the primary source reflected the perspective of a prescriber, patient, or pharmacist or a combined perspective. Terminology and methodological differences were documented among core (essential elements of presented and unpresented prescribing events and claimed and unclaimed dispensing events regardless of setting), supplemental (refined for accuracy), and contextual (setting-specific) design parameters. Recommendations were made to encourage and guide future research. Results: The 45 IMA studies identified used multiple terms for IMA and operationalized measurements differently. Primary data sources reflecting a prescriber's and pharmacist's perspective potentially misclassified core parameters more often with shorter/nonexistent pre- and postperiods (1-14 days) than did a combined perspective. Only a few studies addressed supplemental issues, and minimal contextual information was provided. Conclusions: General recommendations are to use IMA as the standard nomenclature, rigorously identify all data sources, and delineate all design parameters. Specific methodological recommendations include providing convincing evidence that initial prescribing and dispensing events are identified, supplemental parameters incorporating perspective and substitution biases are addressed, and contextual parameters are included.

Does Internet reporting improve the accessibility of financial reporting in a global world? A comparative study of New Zealand and Indian companies

 The accessibility of business reporting, including financial reports on company websites is not necessarily increased by providing more information on websites. The quality of Internet-based information is affected by both the accessibility and quantity of information provided. However, the accessibility of the information is an under researched area. This paper contributes to the existing body of knowledge on webbased business reporting, by considering the dimension of accessibility in terms of website appearance and visual design from four different perspectives. The aim is to consider the differences that occur in website organisation as a way of considering the accessibility of information provided on company websites. The paper considers the differences in the accessibility of website information between New Zealand and Indian companies as a means of demonstrating the variation that can occur across countries as well as within the same reporting structure. We conclude that Internet financial reporting does provide the illusion of comparability but without a more sustained focus on the harmonisation of terminology and attributes included in Internet reporting, the potential for comparison is reduced.

Implementing novel models of posttreatment care for cancer survivors: Enablers, challenges and recommendations

AIM: The American Society of Clinical Oncology and US Institute of Medicine emphasize the need to trial novel models of posttreatment care, and disseminate findings. In 2011, the Victorian State Government (Australia) established the Victorian Cancer Survivorship Program (VCSP), funding six 2-year demonstration projects, targeting end of initial cancer treatment. Projects considered various models, enrolling people of differing cancer types, age and residential areas. We sought to determine common enablers of success, as well as challenges/barriers. METHODS: Throughout the duration of the projects, a formal "community of practice" met regularly to share experiences. Projects provided regular formal progress reports. An analysis framework was developed to synthesize key themes and identify critical enablers and challenges. Two external reviewers examined final project reports. Discussion with project teams clarified content. RESULTS: Survivors reported interventions to be acceptable, appropriate and effective. Strong clinical leadership was identified as a critical success factor. Workforce education was recognized as important. Partnerships with consumers, primary care and community organizations; risk stratified pathways with rapid re-access to specialist care; and early preparation for survivorship, self-management and shared care models supported positive project outcomes. Tailoring care to individual needs and predicted risks was supported. Challenges included: lack of valid assessment and prediction tools; limited evidence to support novel care models; workforce redesign; and effective engagement with community-based care and issues around survivorship terminology. CONCLUSION: The VCSP project outcomes have added to growing evidence around posttreatment care. Future projects should consider the identified enablers and challenges when designing and implementing survivorship care.

Translating research for evidence-based public health: key concepts and future directions

Applying research to guide evidence-based practice is an ongoing and significant challenge for public health. Developments in the emerging field of ‘translation’ have focused on different aspects of the problem, resulting in competing frameworks and terminology. In this paper the scope of ‘translation’ in public health is defined, and four related but conceptually different ‘translation processes’ that support evidence-based practice are outlined: (1) reviewing the transferability of evidence to new settings, (2) translation research, (3) knowledge translation, and (4) knowledge translation research. Finally, an integrated framework is presented to illustrate the relationship between these domains, and priority areas for further development and empirical research are identified.

Reverse logistics in the construction industry

Reverse logistics in construction refers to the movement of products and materials from salvaged buildings to a new construction site. While there is a plethora of studies looking at various aspects of the reverse logistics chain, there is no systematic review of literature on this important subject as applied to the construction industry. Therefore, the objective of this study is to integrate the fragmented body of knowledge on reverse logistics in construction, with the aim of promoting the concept among industry stakeholders and the wider construction community. Through a qualitative meta-analysis, the study synthesises the findings of previous studies and presents some actions needed by industry stakeholders to promote this concept within the real-life context. First, the trend of research and terminology related with reverse logistics is introduced. Second, it unearths the main advantages and barriers of reverse logistics in construction while providing some suggestions to harness the advantages and mitigate these barriers. Finally, it provides a future research direction based on the review.

Small-scale property development: GST implications

The purpose of this article is to explore the GST implications of small-scale property development in Australia and to provide guidance as to whether such activities give rise to a GST liability. The legislation governing the operation of the GST affecting these projects uses the familiar termi- nology of ‘business’, but it also uses terminology such as ‘adventure or concern in the nature of trade’, which has not received extensive consid- eration by the Australian courts. The authors review relevant case law to identify key principles, which will guide the courts in applying this termi- nology to small-scale property development, and provide guidance as to when a taxpayer undertaking such projects will be required to register for GST. The authors also discuss the factors relevant to determining the impact of the timing of registration. The article concludes that small-scale property developers need to be aware of the complexities and uncertainty in relation to the application of the GST to such projects.

'It is not all about sex': young people's views about sexuality and relationships education

The Engaging Young People in Sexuality Education (EYPSE) research project addresses two questions: 1. What are young people’s views on school-based sexuality and relationships education? 2. In what ways could sexuality and relationships education be improved? This report focuses on findings from the first stage of the research project, consisting of an online survey of over 2,000 students in 31 secondary schools in South Australia and Victoria. The research was conducted in government secondary schools in South Australia (14) and Victoria (17). A detailed online survey was constructed and administered to students aged 13 to 16+ years old. The survey used similar terminology and language to that used in sexuality and relationships education classes. A total of 2,325 students undertook the survey. Demographic information about the students includes: - Age – 13 years (18%), 14 years (40%), 15 years (32%), 16+ years (10%) - Location – Victoria (63%), South Australia (37%) - Gender – Female (49%), Male (50%), ‘Other’ (1%) - Sexual attraction – opposite sex (83.5%), same sex (1.4%), both sexes (5.5%), unsure (5.2%), preferred not to disclose (4.3%) - Socio-economic status of the school – low (25.8%), middle (41.9%), high (25.8%), not ranked (6.5%)

Unravelling the muddles of summary dismissal under contracts of employment

This article seeks to address some fundamental errors in the application of contract law to disputes involving the summary dismissal of employees. The pre-existing law which arose out of the master servant era was not absorbed by the contract paradigm. Instead, remnants of the law remained and is still applied today. The decision of Melbourne Stadiums Ltd v Sautner (2015) 229 FCR 221 demonstrates this where the court relied upon concepts arising out of that time to justify the employer's decision to summarily dismiss an employee. The article also considers some more practical matters if the law was to be modernised to accord more strictly with contract principles. It may not necessarily lead to different outcomes, but it will lead to a more cohesive set of principles and avoid the often jumbled terminology used in employment law disputes.

From the inside to the outside. Architecture Venice Biennales 2014 and 2016

The comparison between the Position Statements of the latest two Venice Biennale of Architecture, Fundamentals, directed by Rem Koolhaas in 2014 and Reporting from the front that Alejandro Aravena prepares for 2016, is an evident sign of the internal stress that architectural practice has been suffering during the last decade. Koolhaas intensively focused on the immediate past whilst Aravena presents a Biennalle strongly decided to explore possible alternatives for the future of Architecture. The first one tried to define the core, theessence, the most elemental particles that utterly compose Architecture. The second looks at the boundaries, the periphery, the outskirts, the limits of the discipline. Fundamentals was theoretical, personal, abstract, compact and aesthetic. Reporting from the front will be practical, collective, concrete, permeable and ethical. This fertile antagonism or counterpoint between both approaches is too frequently understood as incompatible. However, as a matter of fact the coexistence of these two different perspectives within architectural practice is the mostdistinctive feature of the complex contemporary architectural landscape. The insertion of the analysis of both position statements within the historical evolution of the Venice Bienale since 1980, allows a reinterpretation of the antagonism between the two exhibitions and evidences some lines of thought and action in the architectural world. Following the war industry terminology that Report from the front has chosen, Aravena identifies with precision the theatre of operations; the space and time that is requesting an urgent response from architecture.Previously Koolhaas had defined the armament that Architecture has available to undertake this crucial mission: to define the role and relevance of Architecture in the immediate future. Until now, battles in the front have been a guerrilla warfare. More reactive than proactive. Battles for survival more than for experience. Necessary but, at the same time, insufficient. Valuable actions in radical contexts; heroic acts in extreme situations; occasional infiltrations that find their final reason for being in their own audacity. Time has come for these counterattackarchitectures to evolve from protests to proposals.

Primary teachers notice the impact of language on children’s mathematical reasoning

Mathematical reasoning is now featured in the mathematics curriculum documents of many nations, but this necessitates changes to teaching practice and hence a need for professional learning. The development of children’s mathematical reasoning requires appropriate encouragement and feedback from their teacher who can only do this if they recognise mathematical reasoning in children’s actions and words. As part of a larger study, we explored whether observation of educators conducting mathematics lessons can develop teachers’ sensitivity in noticing children’s reasoning and consideration of how to support reasoning. In the Mathematical Reasoning Professional Learning Research Program, demonstration lessons were conducted in Australian and Canadian primary classrooms. Data sources included post-lesson group discussions. Observation of demonstration lessons and engagement in post-lesson discussions proved to be effective vehicles for developing a professional eye for noticing children’s individual and whole-class reasoning. In particular, the teachers noticed that children struggled to employ mathematical language to communicate their reasoning and viewed limitations in language as a major barrier to increasing the use of mathematical reasoning in their classrooms. Given the focus of teachers’ noticing of the limitations in some types of mathematical language, it seems that targeted support is required for teachers to facilitate classroom discourse for reasoning.

Finding a unified understanding of nature

A letter to the editor of EcoHealth regarding the 2014 International Union for the Conservation of Nature's World Parks Congress and how the event failed to address a long-lasting vision of protecting the earth's ecosystems.