How significant is partnership formation in area-based projects to increase parental attendance at maternal and child health services

Objectives: 

Unpacking black boxes: Mechanisms and theory building in evaluation

There is growing interest in the concept of ‘‘mechanism’’ across many areas of the social sciences. In the field of program and policy evaluation, a number of scholars have also emphasized the importance of causal mechanisms for explaining how and why programs work. However, there appears to be some ambiguity about the meaning and uses of mechanism-based thinking in both the social science and evaluation literature. In this article we attempt to clarify what is meant by mechanisms in the context of program evaluation by identifying three main characteristics of mechanisms and outlining a possible typology of mechanisms. A number of theoretical and practical implications for evaluators are also discussed, along with some precautions to consider when investigating mechanisms that might plausibly account for program outcomes.

Lower Permian brachiopods from Wasp Head Formation, Sydney Basin, southeastern Australia

Although there is a generally accepted framework for the Permian marine biogeography of Australia, significant uncertainties remain concerning the temporal biogeographical changes closely related to the timing of Permian glacial-interglacial events. Several recent studies along these research lines demonstrate the importance of a reliable high-resolution biostratigraphical timescale for paleobiogeographical and paleoclimatic reconstructions. This paper provides, for the first time, a full taxonomic and biostratigraphical study of the brachiopod fauna from the Wasp Head Formation, southern Sydney Basin, southeastern Australia. The fauna is associated with deposits of the first Permian glacial interval suggested for eastern Australia. Three brachiopod assemblages are recognized. The lower and middle assemblages contain scarce brachiopods although associated bivalves are comparatively more common. Despite very low diversity and low abundance, these two brachiopod assemblages contain characteristic species of the Strophalosia concentrica and Strophalosia subcircularis brachiopod zones, both considered of late Asselian age. The third assemblage, occurring in the uppermost part of the formation, contains more brachiopods than bivalves and is referred to early Sakmarian in age. The species diversity and stratigraphic occurrences of the brachiopod assemblages in relation to sedimentary facies suggest that the lower two assemblages may represent an intra-glacial interval while the younger third assemblage, characterized by abundant occurrences of Trigonotreta and Tomiopsis species, accompanied by the bivalve Eurydesma, is more indicative of a post-glacial benthic marine fauna comparable to coeval brachiopod faunas found elsewhere in Gondwana. © 2014, The Paleontological Society.

Associations between economic hardship and markers of self-management in adults with type 2 diabetes: results from Diabetes MILES - Australia

A socioeconomic gradient exists in Australia for type 2 diabetes mellitus (T2DM). It remains unclear whether economic hardship is associated with T2DM self-management behaviours.

Further investigation of the psychometric properties of the Insulin Treatment Appraisal Scale among insulin-using and non-insulin-using adults with type 2 diabetes : results from Diabetes MILES-Australia

Negative attitudes towards insulin are commonly reported by people with type 2 diabetes mellitus (T2DM) and can act as a barrier to timely insulin initiation. The Insulin Treatment Appraisal Scale (ITAS) is a widely used 20-item measure of attitudes towards insulin. While designed for completion by both insulin using and non-insulin using adults with T2DM, its psychometric properties have not been investigated separately for these groups. Furthermore, the total score is routinely reported in preference to the published two-factor structure (negative/positive appraisals). Further psychometric validation of the ITAS is required to examine its properties.

Subjective wellbeing among adults with diabetes : results from Diabetes MILES—Australia

This study examines the subjective wellbeing of Australian adults with diabetes who completed the Diabetes MILES—Australia survey, investigating by diabetes type and treatment, and by comparing with the subjective wellbeing of the general Australian adult population. In addition, the extent to which depression and socio-demographic factors account for subjective wellbeing is investigated. People with type 1 or type 2 diabetes have significantly lower subjective wellbeing compared to the general population, even after controlling for covariates (demographic and socio-economic status, diabetes duration, body mass index, number of diabetes-related complications, and depression). Furthermore, adults with type 2 diabetes using insulin to manage their condition report the lowest levels of subjective wellbeing, and are also most likely to report dissatisfaction with their current health. These findings suggest that living with diabetes, and in particular, living with type 2 diabetes and using insulin, strongly challenges the maintenance of subjective wellbeing.

Mining allocating patterns in one-sum weighted items

An Association Rule (AR) is a common knowledge model in data mining that describes an implicative cooccurring relationship between two disjoint sets of binary-valued transaction database attributes (items), expressed in the form of an "antecedent⇒ consequent" rule. A variant of the AR is the Weighted Association Rule (WAR). With regard to a marketing context, this paper introduces a new knowledge model in data mining -ALlocating Pattern (ALP). An ALP is a special form of WAR, where each rule item is associated with a weighting score between 0 and 1, and the sum of all rule item scores is 1. It can not only indicate the implicative co-occurring relationship between two (disjoint) sets of items in a weighted setting, but also inform the "allocating" relationship among rule items. ALPs can be demonstrated to be applicable in marketing and possibly a surprising variety of other areas. We further propose an Apriori based algorithm to extract hidden and interesting ALPs from a "one-sum" weighted transaction database. The experimental results show the effectiveness of the proposed algorithm. © 2008 IEEE.

Comparative microarray analysis identifies commonalities in neuronal injury: evidence for oxidative stress, dysfunction of calcium signalling, and inhibition of autophagy-lysosomal pathway

Mitochondrial dysfunction, ubiquitin-proteasomal system impairment and excitotoxicity occur during the injury and death of neurons in neurodegenerative conditions. The aim of this work was to elucidate the cellular mechanisms that are universally altered by these conditions. Through overlapping expression profiles of rotenone-, lactacystin- and N-methyl-D-aspartate-treated cortical neurons, we have identified three affected biological processes that are commonly affected; oxidative stress, dysfunction of calcium signalling and inhibition of the autophagic-lysosomal pathway. These data provides many opportunities for therapeutic intervention in neurodegenerative conditions, where mitochondrial dysfunction, proteasomal inhibition and excitotoxicity are evident.