58 resultados para State Historical Society of Wisconsin.


Relevância:

100.00% 100.00%

Publicador:

Resumo:

The collection documents the history of the Geelong company, Backwell IXL, which commenced in 1858 (first trading under the name E. Backwell & Son) as a blacksmith's shop and stove maker and covers the growth of the business to an appliance, car component and foundry products manufacturer. This collection comprises records, accounts, photographs and product data sheets. It also includes the manuscript of the 'Memoirs of Albert Leslie Backwell', which contained a brief history of the company from the late 1850s to 1980s, including recollections of the management of the company from the early 1920s to the mid 1975s.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

Traces the evolution of the practice and conceptualisations of public diplomacy, especially with reference to India's recent ventures in this field

Relevância:

100.00% 100.00%

Publicador:

Resumo:

Objective:  Alterations in gene expression in bipolar disorder have been found in numerous studies. It is unclear whether such alterations are related to specific mood states. As a biphasic disorder, mood state-related alterations in gene expression have the potential to point to markers of disease activity, and trait-related alterations might indicate vulnerability pathways. This review therefore evaluated the evidence for whether gene expression in bipolar disorder is state or trait related.

Methods:  A systematic review, using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guideline for reporting systematic reviews, based on comprehensive database searches for studies on gene expression in patients with bipolar disorder in specific mood states, was conducted. We searched Medline, Embase, PsycINFO, and The Cochrane Library, supplemented by manually searching reference lists from retrieved publications.

Results:  A total of 17 studies were included, comprising 565 patients and 418 control individuals. Six studies evaluated intraindividual alterations in gene expression across mood states. Two of five studies found evidence of intraindividual alterations in gene expression between a depressed state and a euthymic state. No studies evaluated intraindividual differences in gene expression between a manic state and a euthymic state, while only one case study evaluated differences between a manic state and a depressed state, finding altered expression in seven genes. No study investigated intraindividual variations in gene expression between a euthymic state and multiple states of various polarities (depressive, manic, hypomanic). Intraindividual alterations in expression of the same genes were not investigated across studies. Only one gene (the brain-derived neurotrophic factor gene; BDNF) was investigated across multiple studies, showing no alteration between bipolar disorder patients and control individuals.

Conclusions:  There is evidence of some genes exhibiting state-related alterations in expression in bipolar disorder; however, this finding is limited by the lack of replication across studies. Further prospective studies are warranted, measuring gene expression in various affective phases, allowing for assessment of intraindividual differences.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

After an extended period of sporadic sightings of small numbers of king penguins at the Falkland Islands, they established themselves on Volunteer Point, situated at the north-east of the islands, by the late 1970s. By 1980, a small breeding population was present which yielded some 40 fledglings during that same year. Since 1991, the population has been monitored annually and the resulting fledgling counts analysed to assess population trends. The population demonstrated a significant increase over the past three decades, at about 10% per annum, with time explaining 75% of the variation in count data. The current population is estimated to be 720 breeding pairs. Despite several authors having alluded to the existence of a large colony of king penguins at the Falklands prior to human exploitation, we found no evidence in support of this. We furthermore found no evidence in the literature in support of exploitation for king penguin oil during the 19th century. Unlike at other breeding sites, increasing numbers of king penguins at the Falklands is consequently unlikely to be a recovery response following exploitation, but rather an indication of either increased immigration or of improved feeding conditions.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

Currently there is a dearth of research into Australian Indigenous knowledge and their understanding of climate change especially in regard to how it fits into an Indigenous world view. Recent discussions by the National Climate Change Adaptation Research Facility (NCCARF) have highlighted this deficiency and also the need to source projects that address this perspective, and enable the incorporation of traditional ecological knowledge into the planning of climate change adaption strategies. Within this context, this paper examines the use and understanding of landscape, both urban and regional, surrounding Port Phillip Bay and the risks and opportunities climate change adaptation brings to the local Indigenous communities. This paper comprises a literature review and proposes further research with the Wurundjeri (Yarra Valley), Wathaurong (Geelong-Bellarine Peninsula) & Boon Wurrung (Mornington Peninsula - Westerport - southern Melbourne) which aim to elicit a contemporary and local response to issues raised by NCCARF but importantly to articulate a possible Indigenous position about the formation, change and direction that Port Phillip Bay and its environs should take from their perspectives. The research looks to draw on how these communities have adapted to climate change physically, mentally and spiritually over their long habitation of the region and their perceptions of climate change this century. The project looks to uncover a longitudinal perspective of adaptation focused upon Indigenous views of 'country' and custodial obligations to 'country' including accumulated cultural and environmental histories, and how this can inform the contemporary practice of landscape architecture and the design of resilient and sustainable human environments.