Understanding success in indigenous entrepreneurship : an exploratory investigation

In Canada there are numerous studies about indigenous Entrepreneurship, most descriptive with little theory development or testing, This leaves a gap in the information available to researchers, policy makers and practitioners. In this paper we describe a research program intended to address this gap beginning with the activities of the Lac La Ronge Indian Band, considered an exemplar of successful indigenous entrepreneurship. From these activities, we draw propositions about indigenous entrepreneurship that are compatible with generic theory. Finally, we describe how we will move from these propositions to a model of indigenous entrepreneurship using grounded theory and structural equation modelling.

Genome - wide association study identifies novel breast cancer susceptibility loci

Breast cancer exhibits familial aggregation, consistent with variation in genetic susceptibility to the disease. Known susceptibility genes account for less than 25% of the familial risk of breast cancer, and the residual genetic variance is likely to be due to variants conferring more moderate risks. To identify further susceptibility alleles, we conducted a two-stage genome-wide association study in 4,398 breast cancer cases and 4,316 controls, followed by a third stage in which 30 single nucleotide polymorphisms (SNPs) were tested for confirmation in 21,860 cases and 22,578 controls from 22 studies. We used 227,876 SNPs that were estimated to correlate with 77% of known common SNPs in Europeans at r² > 0.5. SNPs in five novel independent loci exhibited strong and consistent evidence of association with breast cancer (P < 10^-7). Four of these contain plausible causative genes (FGFR2, TNRC9, MAP3K1 and LSP1). At the second stage, 1,792 SNPs were significant at the P < 0.05 level compared with an estimated 1,343 that would be expected by chance, indicating that many additional common susceptibility alleles may be identifiable by this approach.

Robert Boyle's theory of nature, with reference to his understanding of natural laws

Argues that the theory of nature-cum-theology and the view of of natural laws of the 17th century natural philosopher, Robert Boyle, were more complex and eclectic than is usually believed. Support is given for construing Boyle as a more complex thinker than previous scholars have suggested.

Zwitterionic additives for electrochemical devices

Zwitterionic electrolytes such as N-methyl-N-(n-butanesulfonate) pyrrolidinium are added to electrolyte compositions such as polyelectrolytes, ionic liquid electrolytes and molecular solvent electrolytes (for example, lithium hexafluorophosphate) to improve conductivity of the ion species, such as lithium, in the electrolyte. This has application to lithium based energy storage devices such as batteries and supercapacitors.

ZWITTERIONIC ADDITIVES FOR ELECTROCHEMICAL DEVICES

Zwitterionic electrolytes such as N-methyl-N-(n-butanesulfonate) pyrrolidinium are added to electrolyte compositions such as polyelectrolytes, ionic liquid electrolytes and molecular solvent electrolytes (for example, lithium hexafluorophosphate) to improve conductivity of the ion species, such as lithium, in the electrolyte. This has application to lithium based energy storage devices such as batteries and supercapacitors.

Double layer structure of ionic liquids at the Au(111) electrode interface : an atomic force microscopy investigation

The double layer structure of two ionic liquids (ILs), 1-butyl-1- methylpyrrolidinium tris(pentafluoroethyl)trifluorophosphate ([Py ₁,₄]FAP) and 1-ethyl-3-methylimidazolium tris(pentafluoroethyl) trifluorophosphate ([EMIm]FAP) at the polarized Au(111) electrode interface is probed using Atomic Force Microscopy force measurements. The force-separation profiles suggest a multilayered morphology is present at the electrified Au(111)-IL interface, with more near surface layers detected at higher potentials. At the (slightly negative) open circuit potential, multiple ion layers are present, and the innermost layer, in contact with the Au(111) surface, is enriched in the cation due to electrostatic adsorption. Upon applying negative electrode potentials (-1.0 V, -2.0 V), stronger IL near surface structure is detected: both the number of ion layers and the force required to rupture these layers increases. Positive electrode potentials (+1.0 V, +2.0 V) also enhance IL near surface structure, but not as much as negative potentials, because surface-adsorbed anions are less effective at templating structure in subsequent layers than cations. This interfacial structure is not consistent with a double layer in the Stern-Gouy-Chapman sense, as there is no diffuse layer. The structure is consistent with a capicitative double-layer model, with a very small separation distance between the planes of charge.