62 resultados para Printing.


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The toppling of Saddam in 2003 has seen Iraq shift from only a handful of state organs that served as propaganda machines, to a wealth of over 200 Iraqi-owned newspapers which are being fervently produced and avidly read on the streets of the nation. This paper traces the introduction of the printing press to Iraq by the Ottomans and details both the periods where Iraq’s press was truly free and fostered the emergence of a civil society and democratic reforms and those where the Iraqi media was most restricted and did little else than praise the regime at hand. Following on, this paper reviews the developments since the fall of Saddam Hussein and, despite the extensive interference in Iraq’s media sector from the occupying forces, it concludes by arguing that these papers have been central to the re-emergence of an Iraqi public sphere which has openly debated and discussed the issues surrounding the nation’s shift from despotism to democracy.

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Despite a wealth of recent research which has detailed the impact that new media outlets and technologies have had on the Middle East’s nascent public sphere and its role in promoting democracy, there has been little investigation into the re-emergence of the free press in Iraq following the toppling of Saddam Hussein in 2003 and the corresponding end to his tight control over the nation’s media sector. This paper begins by reviewing Iraq’s long relationship with the written word and its corresponding public sphere. It traces the introduction of the printing press to Iraq by the Ottomans and details those periods when the Iraqi press was truly free, fostering the emergence of a civil society and democratic reforms (such as under the Young Turks, the early Hashemite era and following the Second World War). It also examines those periods when the Iraqi media was most restricted and did little else than praise the regime at hand (such as under Ottoman rule and most recently under the Ba†th regime, especially under Saddam Hussein). Following on, this article reviews the developments since the fall of Saddam Hussein and, despite the extensive interference in Iraq’s media sector from governmental entities both outside and inside Iraq, it concludes by arguing that these papers have been central to the re-emergence of an Iraqi public sphere which has openly debated and discussed the issues pertinent to post-Saddam Iraq.

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The modification of an interface on a molecular level with more than one molecular ‘building block' is essentially an example of the ‘bottom–up' fabrication principle of nanotechnology. The fabrication of such integrated molecular systems in electrochemistry has seen rapid progress in recent years via the development of sensing interfaces fabricated using self-assembled monolayers (SAMs). This review outlines recent advances and applications of self-assembled monolayers for modifying electrodes with an emphasis on the development of integrated molecular systems. First, some basic issues regarding fabricating integrated molecular systems, such as the role of the surface topography of the electrode and patterning surfaces, are discussed. Subsequently an overview of recent developments in pH, inorganic and bio sensing involving the use of SAMs is given. Finally emerging trends in using molecular building blocks in the fabrication of integrated molecular systems, such as nanotubes, dendrimers and nanoparticles, are reviewed.

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A human peroxisome proliferator-activated receptor alpha ligand binding domain (PPARαLBD)-maltose binding protein fusion construct was expressed in Escherichia coli. A codon optimized DNA sequence encoding human PPARαLBD (aa196–468) was synthesized and ligated into the pDEST17 E. coli expression vector downstream of a MBP solubility fusion tag and an intermittent TEV protease cleavage site. Following auto-induction at 28 °C, PPARαLBD protein was purified to electrophoretic homogeneity by a nickel affinity chromatographic step, on-column TEV protease cleavage followed by Sephacryl S200 size exclusion chromatography. The recombinant protein displayed cross-reactivity with goat anti-(human PPARα) polyclonal antibody and was identified as human PPARα by trypic peptide mass finger-printing. The addition of a PPARα specific ligand (fenofibric acid, GW7647 or GW590735) to the growth media significantly stabilized the PPARαLBD structure and enhanced the expression of soluble protein. In-cell ligand binding was examined by monitoring the enhancement of PPARαLBD expression as a function of the concentration of ligand in the growth media. The efficient expression and in-cell assay of the reported PPARαLBD construct make it amenable to high through-put screening assays in drug discovery programs.

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Background

This project occurred during the course of the Translating Research in Elder Care (TREC) program of research. TREC is a multilevel and longitudinal research program being conducted in the three Canadian Prairie Provinces of Alberta, Saskatchewan, and Manitoba. The main purpose of TREC is to increase understanding about the role of organizational context in influencing knowledge use in residential long-term care settings. The purpose of this study was to evaluate healthcare aides’ (HCAs) perceptions of a one-page poster designed to feed back aggregated data (including demographic information and perceptions about influences on best practice) from the TREC survey they had recently completed.

Methods
A convenience sample of 7 of the 15 nursing homes participating in the TREC research program in Alberta were invited to participate. Specific facility-level summary data were provided to each facility in the form of a one-page poster report. Two weeks following delivery of the report, a convenience sample of HCAs was surveyed using one-to-one structured interviews.

Results
One hundred twenty-three HCAs responded to the evaluation survey. Overall, HCAs’ opinions about presentation of the feedback report and the understandability, usability, and usefulness of the content were positive. For each report, analysis of data and production and inspection of the report took up to one hour. Information sessions to introduce and explain the reports averaged 18 minutes. Two feedback reports (minimum) were supplied to each facility at a cost of CAN$2.39 per report, for printing and laminating.

Conclusions
This study highlights not only the feasibility of producing understandable, usable, and useful feedback reports of survey data but also the value and importance of providing feedback to survey respondents. More broadly, the findings suggest that modest strategies may have a positive and desirable effect in participating sites.