Classification of healthcare data using genetic fuzzy logic system and wavelets

Healthcare plays an important role in promoting the general health and well-being of people around the world. The difficulty in healthcare data classification arises from the uncertainty and the high-dimensional nature of the medical data collected. This paper proposes an integration of fuzzy standard additive model (SAM) with genetic algorithm (GA), called GSAM, to deal with uncertainty and computational challenges. GSAM learning process comprises three continual steps: rule initialization by unsupervised learning using the adaptive vector quantization clustering, evolutionary rule optimization by GA and parameter tuning by the gradient descent supervised learning. Wavelet transformation is employed to extract discriminative features for high-dimensional datasets. GSAM becomes highly capable when deployed with small number of wavelet features as its computational burden is remarkably reduced. The proposed method is evaluated using two frequently-used medical datasets: the Wisconsin breast cancer and Cleveland heart disease from the UCI Repository for machine learning. Experiments are organized with a five-fold cross validation and performance of classification techniques are measured by a number of important metrics: accuracy, F-measure, mutual information and area under the receiver operating characteristic curve. Results demonstrate the superiority of the GSAM compared to other machine learning methods including probabilistic neural network, support vector machine, fuzzy ARTMAP, and adaptive neuro-fuzzy inference system. The proposed approach is thus helpful as a decision support system for medical practitioners in the healthcare practice.

Structural classification of proteins through amino acid sequence using interval type-2 fuzzy logic system

This paper introduces a new multi-output interval type-2 fuzzy logic system (MOIT2FLS) that is automatically constructed from unsupervised data clustering method and trained using heuristic genetic algorithm for a protein secondary structure classification. Three structure classes are distinguished including helix, strand (sheet) and coil which correspond to three outputs of the MOIT2FLS. Quantitative properties of amino acids are used to characterize the twenty amino acids rather than the widely used computationally expensive binary encoding scheme. Amino acid sequences are parsed into learnable patterns using a local moving window strategy. Three clustering tasks are performed using the adaptive vector quantization method to derive an equal number of initial rules for each type of secondary structure. Genetic algorithm is applied to optimally adjust parameters of the MOIT2FLS with the purpose of maximizing the Q3 measure. Comprehensive experimental results demonstrate the strong superiority of the proposed approach over the traditional methods including Chou-Fasman method, Garnier-Osguthorpe-Robson method, and artificial neural network models.

An interval type-2 fuzzy logic system-based method for prediction interval construction

This paper introduces a new non-parametric method for uncertainty quantification through construction of prediction intervals (PIs). The method takes the left and right end points of the type-reduced set of an interval type-2 fuzzy logic system (IT2FLS) model as the lower and upper bounds of a PI. No assumption is made in regard to the data distribution, behaviour, and patterns when developing intervals. A training method is proposed to link the confidence level (CL) concept of PIs to the intervals generated by IT2FLS models. The new PI-based training algorithm not only ensures that PIs constructed using IT2FLS models satisfy the CL requirements, but also reduces widths of PIs and generates practically informative PIs. Proper adjustment of parameters of IT2FLSs is performed through the minimization of a PI-based objective function. A metaheuristic method is applied for minimization of the non-linear non-differentiable cost function. Performance of the proposed method is examined for seven synthetic and real world benchmark case studies with homogenous and heterogeneous noise. The demonstrated results indicate that the proposed method is capable of generating high quality PIs. Comparative studies also show that the performance of the proposed method is equal to or better than traditional neural network-based methods for construction of PIs in more than 90% of cases. The superiority is more evident for the case of data with a heterogeneous noise. © 2014 Elsevier B.V.

Building fuzzy inference systems with similarity reasoning : NSGAII-based fuzzy rule selection and evidential functions

In our previous investigations, two Similarity Reasoning (SR)-based frameworks for tackling real-world problems have been proposed. In both frameworks, SR is used to deduce unknown fuzzy rules based on similarity of the given and unknown fuzzy rules for building a Fuzzy Inference System (FIS). In this paper, we further extend our previous findings by developing (1) a multi-objective evolutionary model for fuzzy rule selection; and (2) an evidential function to facilitate the use of both frameworks. The Non-Dominated Sorting Genetic Algorithms-p (NSGA-p) is adopted for fuzzy rule selection, in accordance with the Pareto optimal criterion. Besides that, two new evidential functions are developed, whereby given fuzzy rules are considered as evidence. Simulated and benchmark examples are included to demonstrate the applicability of these suggestions. Positive results were obtained.

Medical data classification using interval type-2 fuzzy logic system and wavelets

This paper introduces an automated medical data classification method using wavelet transformation (WT) and interval type-2 fuzzy logic system (IT2FLS). Wavelet coefficients, which serve as inputs to the IT2FLS, are a compact form of original data but they exhibits highly discriminative features. The integration between WT and IT2FLS aims to cope with both high-dimensional data challenge and uncertainty. IT2FLS utilizes a hybrid learning process comprising unsupervised structure learning by the fuzzy c-means (FCM) clustering and supervised parameter tuning by genetic algorithm. This learning process is computationally expensive, especially when employed with high-dimensional data. The application of WT therefore reduces computational burden and enhances performance of IT2FLS. Experiments are implemented with two frequently used medical datasets from the UCI Repository for machine learning: the Wisconsin breast cancer and Cleveland heart disease. A number of important metrics are computed to measure the performance of the classification. They consist of accuracy, sensitivity, specificity and area under the receiver operating characteristic curve. Results demonstrate a significant dominance of the wavelet-IT2FLS approach compared to other machine learning methods including probabilistic neural network, support vector machine, fuzzy ARTMAP, and adaptive neuro-fuzzy inference system. The proposed approach is thus useful as a decision support system for clinicians and practitioners in the medical practice. copy; 2015 Elsevier B.V. All rights reserved.

Multi-output interval type-2 fuzzy logic system for protein secondary structure prediction

A new multi-output interval type-2 fuzzy logic system (MOIT2FLS) is introduced for protein secondary structure prediction in this paper. Three outputs of the MOIT2FLS correspond to three structure classes including helix, strand (sheet) and coil. Quantitative properties of amino acids are employed to characterize twenty amino acids rather than the widely used computationally expensive binary encoding scheme. Three clustering tasks are performed using the adaptive vector quantization method to construct an equal number of initial rules for each type of secondary structure. Genetic algorithm is applied to optimally adjust parameters of the MOIT2FLS. The genetic fitness function is designed based on the Q3 measure. Experimental results demonstrate the dominance of the proposed approach against the traditional methods that are Chou-Fasman method, Garnier-Osguthorpe-Robson method, and artificial neural network models.

Fuzzy logic controller and cascade inverter for direct torque control of IM

In this paper, a five-level cascaded H-bridge multilevel inverters topology is applied on induction motor control known as direct torque control (DTC) strategy. More inverter states can be generated by a five-level inverter which improves voltage selection capability. This paper also introduces two different control methods to select the appropriate output voltage vector for reducing the torque and flux error to zero. The first is based on the conventional DTC scheme using a pair of hysteresis comparators and look up table to select the output voltage vector for controlling the torque and flux. The second is based on a new fuzzy logic controller using Sugeno as the inference method to select the output voltage vector by replacing the hysteresis comparators and lookup table in the conventional DTC, to which the results show more reduction in torque ripple and feasibility of smooth stator current. By using Matlab/Simulink, it is verified that using five-level inverter in DTC drive can reduce the torque ripple in comparison with conventional DTC, and further torque ripple reduction is obtained by applying fuzzy logic controller. The simulation results have also verified that using a fuzzy controller instead of a hysteresis controller has resulted in reduction in the flux ripples significantly as well as reduces the total harmonic distortion of the stator current to below 4 %.

Implementation of fuzzy logic maximum power point tracking controller for photovoltaic system

In this study, simulation and hardware implementation of Fuzzy Logic (FL) Maximum Power Point Tracking (MPPT) used in photovoltaic system with a direct control method are presented. In this control system, no proportional or integral control loop exists and an adaptive FL controller generates the control signals. The designed and integrated system is a contribution of different aspects which includes simulation, design and programming and experimental setup. The resultant system is capable and satisfactory in terms of fastness and dynamic performance. The results also indicate that the control system works without steady-state error and has the ability of tracking MPPs rapid and accurate which is useful for the sudden changes in the atmospheric condition. MATLAB/Simulink software is utilized for simulation and also programming the TMS320F2812 Digital Signal Processor (DSP). The whole system designed and implemented to hardware was tested successfully on a laboratory PV array. The obtained experimental results show the functionality and feasibility of the proposed controller.

Fuzzy logic controller optimized by particle swarm optimization for DC motor speed control

In this paper, we presented an optimized fuzzy logic controller using particle swarm optimization for DC motor speed control. The controller model is simulated using MATLAB software and also experimentally tested on a laboratory DC motor. A comparison of the performance of different controllers such as PID controller, fuzzy logic controller and optimized fuzzy logic controller is presented as well. With reference to the results of digital simulations and experiment, the designed FLC-PSO speed controller obtains much better dynamic behavior compared to PID and the normal FLC designed. Moreover, it can acquire superior performance of the DC motor, and also perfect speed tracking with no overshoot. The optimized membership functions (MFs) are obviously proved to be able to provide a better performance and higher robustness in comparison with a regular fuzzy model, when the MFs were heuristically defined. Besides, experimental results verify the ability of proposed FLC under sudden change of the load torque which leads to speed variances.

Switch point finding using polynomial regression for fuzzy type reduction algorithms

Karnik-Mendel (KM) algorithm is the most widely used type reduction (TR) method in literature for the design of interval type-2 fuzzy logic systems (IT2FLS). Its iterative nature for finding left and right switch points is its Achilles heel. Despite a decade of research, none of the alternative TR methods offer uncertainty measures equivalent to KM algorithm. This paper takes a data-driven approach to tackle the computational burden of this algorithm while keeping its key features. We propose a regression method to approximate left and right switch points found by KM algorithm. Approximator only uses the firing intervals, rnles centroids, and FLS strnctural features as inputs. Once training is done, it can precisely approximate the left and right switch points through basic vector multiplications. Comprehensive simulation results demonstrate that the approximation accuracy for a wide variety of FLSs is 100%. Flexibility, ease of implementation, and speed are other features of the proposed method.

A congestion control scheme based on fuzzy logic in wireless body area networks

One of the major challenges in healthcare wireless body area network (WBAN) applications is to control congestion. Unpredictable traffic load, many-to-one communication nature and limited bandwidth occupancy are among major reasons that can cause congestion in such applications. Congestion has negative impacts on the overall network performance such as packet losses, increasing end-to-end delay and wasting energy consumption due to a large number of retransmissions. In life-critical applications, any delay in transmitting vital signals may lead to death of a patient. Therefore, in order to enhance the network quality of service (QoS), developing a solution for congestion estimation and control is imperative. In this paper, we propose a new congestion detection and control protocol for remote monitoring of patients health status using WBANs. The proposed system is able to detect congestion by considering local information such as buffer capacity and node rate. In case of congestion, the proposed system differentiates between vital signals and assigns priorities to them based on their level of importance. As a result, the proposed approach provides a better quality of service for transmitting highly important vital signs.

Hybrid model for the training of interval type-2 fuzzy logic system

In this paper, a hybrid training model for interval type-2 fuzzy logic system is proposed. The hybrid training model uses extreme learning machine to tune the consequent part parameters and genetic algorithm to optimize the antecedent part parameters. The proposed hybrid learning model of interval type-2 fuzzy logic system is tested on the prediction of Mackey-Glass time series data sets with different levels of noise. The results are compared with the existing models in literature; extreme learning machine and Kalman filter based learning of consequent part parameters with randomly generated antecedent part parameters. It is observed that the interval type-2 fuzzy logic system provides improved performance with the proposed hybrid learning model.

Modified AHP for gene selection and cancer classification using type-2 fuzzy logic

This paper proposes a modification to the analytic hierarchy process (AHP) to select the most informative genes that serve as inputs to an interval type-2 fuzzy logic system (IT2FLS) for cancer classification. Unlike the conventional AHP, the modified AHP allows us to process quantitative factors that are ranking outcomes of individual gene selection methods including t-test, entropy, receiver operating characteristic curve, Wilcoxon test, and signal-to-noise ratio. The IT2FLS is introduced for the classification task due to its great ability for handling nonlinear, noisy, and outlier data, which are common problems in cancer microarray gene expression profiles. An unsupervised learning strategy using the fuzzy c-means clustering is employed to initialize parameters of the IT2FLS. Other classifiers such as multilayer perceptron network, support vector machine, and fuzzy ARTMAP are also implemented for comparisons. Experiments are carried out on three well-known microarray datasets: diffuse large B-cell lymphoma, leukemia cancer, and prostate. Rather than the traditional cross validation, leave-one-out cross-validation strategy is applied for the experiments. Results demonstrate the performance dominance of the IT2FLS against the competing classifiers. More noticeably, the modified AHP improves the classification performance not only of the IT2FLS but of all other classifiers as well. Accordingly, the proposed combination between the modified AHP and IT2FLS is a powerful tool for cancer classification and can be implemented as a real clinical decision support system that is useful for medical practitioners.

Evaluation and comparison of type reduction algorithms from a forecast accuracy perspective

A variety of type reduction (TR) algorithms have been proposed for interval type-2 fuzzy logic systems (IT2 FLSs). The focus of existing literature is mainly on computational requirements of TR algorithm. Often researchers give more rewards to computationally less expensive TR algorithms. This paper evaluates and compares five frequently used TR algorithms from a forecasting performance perspective. Algorithms are judged based on the generalization power of IT2 FLS models developed using them. Four synthetic and real world case studies with different levels of uncertainty are considered to examine effects of TR algorithms on forecasts accuracies. It is found that Coupland-Jonh TR algorithm leads to models with a better forecasting performance. However, there is no clear relationship between the width of the type reduced set and TR algorithm.

Effects of type reduction algorithms on forecasting accuracy of IT2FLS models

Type reduction (TR) is one of the key components of interval type-2 fuzzy logic systems (IT2FLSs). Minimizing the computational requirements has been one of the key design criteria for developing TR algorithms. Often researchers give more rewards to computationally less expensive TR algorithms. This paper evaluates and compares five frequently used TR algorithms based on their contribution to the forecasting performance of IT2FLS models. Algorithms are judged based on the generalization power of IT2FLS models developed using them. Synthetic and real world case studies with different levels of uncertainty are considered to examine effects of TR algorithms on forecasts' accuracies. As per obtained results, Coupland-Jonh TR algorithm leads to models with a higher and more stable forecasting performance. However, there is no obvious and consistent relationship between the widths of the type reduced set and the TR algorithm. © 2013 Elsevier B.V.