89 resultados para Directed Movements


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Ultramodernity (Willaime 2006), following on from modernity, has been characterised as an era of fear, risk and uncertainty and paradoxically as a time of great hope and global interdependence (Baumann 2006; Beck 2006; Obama 2006). Following the events of September 11, 2001, the Bali and London bombings, a climate of fear has inspired a plethora of policies that have eroded civil liberties, jeopardising trust in state systems and thereby inadvertently elevating the risk of further violence, particularly in so-called Western societies. Conversely, ultramodern scholars, including Jürgen Habermass and Ulrich Beck, have advocated cosmopolitan solutions to more effectively and cooperatively counter global risks. These optimistic scenarios, while reaching populist proportions, have also received their fare share of criticism (Brassett 2008). Indeed, when we look toward the current state of the United Nations it is difficult not to lose hope. Where is the proof that Immanuel Kant’s cosmopolitan condition is coming into being in the global arena beyond these sociological theories? I argue that the rise of multifaith movements in ultramodernity provides this much needed evidence.

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The ultramodern era has been characterized paradoxically as one of great fear and great hope. Reactions to the tragic events of September 11, 2001 provide evidence of this ambivalence whereby a politics of fear and exclusion permeated Western societies, accompanied by a growing interest in collaborative cosmopolitan solutions addressing the most pressing global risks of our times. Culturally, religiously and linguistically diverse (CRALD) community experiences in the state of Victoria, Australia well illustrate this dichotomy. Drawing on this case study, I argue that the rise of multifaith and multi-actor peacebuilding networks in ultramodernity provide evidence that cosmopolitan solutions can effectively counter global risks, in this case particularly terrorism, and advance common security among diverse faith communities and across diverse sectors. In so doing I develop a new netpeace framework arguing that the politics of fear is best countered by a politics of understanding.

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One of the possible models of the human visual system (HVS) in the computer vision literature has a high resolution fovea and exponentially decreasing resolution periphery. The high resolution fovea is used to extract necessary information in order to solve a vision task and the periphery may be used to detect motion. To obtain the desired information, the fovea is guided by the contents of the scene and other knowledge to position the fovea over areas of interest. These eye movements are called saccades and corrective saccades. A two stage process has been implemented as a mechanism for changing foveation in log polar space. Initially, the open loop stage roughly foveates on the best interest feature and then the closed loop stage is invoked to accurately iteratively converge onto the foveation point. The open loop stage developed for the foveation algorithm is applied to saccadic eye movements and a tracking system. Log polar space is preferred over Cartesian space as: (1) it simultaneously provides high resolution and a wide viewing angle; and (2) feature invariance occurs in the fovea which simplifies the foveation process.

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Chris Steyaert and Daniel Hjorth (Eds) (2007) Entrepreneurship as Social Change: A Third Movements in Entrepreneurship Book, Edward Elgar, Cheltenham, United Kingdom

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Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and depression are considered to be neuro-immune disorders (Maes and Twisk, BMC Medicine 8:35, 2010). There is also evidence that depression and ME/CFS are accompanied by oxidative and nitrosative stress (O&NS) and by increased autoantibodies to a number of self-epitopes some of which have become immunogenic due to damage by O&NS. The aim of this study is to examine IgM-mediated autoimmune responses to different self-epitopes in ME/CFS versus depression. We examined serum IgM antibodies to three anchorage molecules (palmitic and myristic acid and S-farnesyl-L-cysteine); acetylcholine; and conjugated NO-modified adducts in 26 patients with major depression; 16 patients with ME/CFS, 15 with chronic fatigue; and 17 normal controls. Severity of fatigue and physio-somatic (F&S) symptoms was measured with the Fibromyalgia and Chronic Fatigue Syndrome Rating Scale. Serum IgM antibodies to the three anchorage molecules and NO-phenylalanine were significantly higher in ME/CFS than in depression. The autoimmune responses to oxidatively, but not nitrosatively, modified self-epitopes were significantly higher in ME/CFS than in depression and were associated with F&S symptoms. The autoimmune activity directed against conjugated acetylcholine did not differ significantly between ME/CFS and depression, but was greater in the patients than controls. Partially overlapping pathways, i.e. increased IgM antibodies to a multitude of neo-epitopes, underpin both ME/CFS and depression, while greater autoimmune responses directed against anchorage molecules and oxidatively modified neo-epitopes discriminate patients with ME/CFS from those with depression. These autoimmune responses directed against neoantigenic determinants may play a role in the dysregulation of key cellular functions in both disorders, e.g. intracellular signal transduction, cellular differentiation and apoptosis, but their impact may be more important in ME/CFS than in depression.

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The double-stranded RNA-activated protein kinase R (PKR) is a key regulator of the innate immune response. Activation of PKR during viral infection culminates in phosphorylation of the α subunit of the eukaryotic translation initiation factor 2 (eIF2α) to inhibit protein translation. A broad range of regulatory functions has also been attributed to PKR. However, as few additional PKR substrates have been identified, the mechanisms remain unclear. Here, PKR is shown to interact with an essential RNA helicase, RHA. Moreover, RHA is identified as a substrate for PKR, with phosphorylation perturbing the association of the helicase with double-stranded RNA (dsRNA). Through this mechanism, PKR can modulate transcription, as revealed by its ability to prevent the capacity of RHA to catalyze transactivating response (TAR)–mediated type 1 human immunodeficiency virus (HIV-1) gene regulation. Consequently, HIV-1 virions packaged in cells also expressing the decoy RHA peptides subsequently had enhanced infectivity. The data demonstrate interplay between key components of dsRNA metabolism, both connecting RHA to an important component of innate immunity and delineating an unanticipated role for PKR in RNA metabolism.

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We examined the variation in foraging movements in a population of young-of-the-year (YOY) brook charr living in the near-shore littoral zone of a lake. By repeating the methodology of an earlier stream study, we made direct comparisons between data from lake and stream populations. In general, the pattern of variation in foraging movements was similar between the two sites with greater variability and activity observed in the lake population. The dichotomous nature of the proportion of time spent moving in the stream was also observed in the lake population but in a reversal of the stream pattern. Charr that moved constantly while foraging represented the largest movement category in the lake. In general, variation in foraging movements were more strongly related to the rate of prey rejection, whereas environmental factors, such as distance from shore, submerged objects, and the amount of overhead riparian cover, were more strongly related to prey ingestion. This last finding directly contrasts with that found in the stream literature for YOY charr in still water where ingestion rate, as estimated using feeding attempt rate, increases with the mobility of YOY charr.

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 Problem based learning has been implemented as a pedagogical tool world-wide across a range of health professions since its inception at McMaster University, Canada, in 1969 (Neville & Norman, 2007). In addition to enhancing knowledge and understanding it is also claimed that PBL develops communication skills, encourages teamwork, sharing of information and respect for others, furthers problem solving skills, and allows students to assume responsibility for their own learning (Wood, 2003). However, the cognitive outcomes of PBL and traditional pedagogy (based on didactic teaching) are similar and hence widespread adoption of PBL has been questioned (see Colliver, 2000). Criticisms of PBL include its resource hungry nature, requiring, as it does, experienced tutors to facilitate .learning across several clusters of students dealing with the same problem. Given the actual and anticipated increase in numbers of medical students in Australia other strategies that retain the advantages of PBL, while minimising the demands on faculty, should now be explored. This paper reports our experience with a modification of the traditional PBL approach, termed PBLplus. This innovation was trialled in a regional clinical school, attached to a hospital, with a group of 19 graduate entry students, who had completed an integrated Year 1 / 2 of the MBBS. PBLplus involved allocating students from the whole class to three task directed groups. Groups had specified assignments to complete to facilitate learning across the whole class. A tutor listened to student presentations and provided an interactive presentation. Hence use of tutors was made more efficient, and faculty input was more specialised.

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The aim of the article is to analyse the secessionist phenomenon by applying the concept of hegemony. Based on critical realist interpretations of the concept, it is argued that hegemonic practice incorporates both inter-subjective and structural aspects. The inter-subjective aspect of hegemony places emphasis on the relations between social groups and the way hegemonic practice leads social agents towards political projects that secure consensus in favour of the interest of particular elites. The structural character of hegemonic practice is evident in the reproduction of social conditions and values that underlie the relations between social agents both globally and domestically. Accordingly, the inter-subjective character of secession as hegemonic practice is evident in the organization of social agents towards a political option (territorial separatism) to the extent that it serves the goals of certain elites. The sturctural aspect of secessionist practice is hegeminic because it reproduces international structures that tend to associate political organization with ethnicity at the state level. The analysis then turns to the case study of Transnistria in Moldova as an empirical illustration of the two tendencies of hegemonic practice in secessionist politics leading ot useful conclusions both for the case study in particular and the study of secession in general. 

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During the reproductive season, sea turtles use a restricted area in the vicinity of their nesting beaches, making them vulnerable to predation. At Raine Island (Australia), the highest density green turtle Chelonia mydas rookery in the world, tiger sharks Galeocerdo cuvier have been observed to feed on green turtles, and it has been suggested that they may specialise on such air-breathing prey. However there is little information with which to examine this hypothesis. We compared the spatial and temporal components of movement behaviour of these two potentially interacting species in order to provide insight into the predator-prey relationship. Specifically, we tested the hypothesis that tiger shark movements are more concentrated at Raine Island during the green turtle nesting season than outside the turtle nesting season when turtles are not concentrated at Raine Island. Turtles showed area-restricted search behaviour around Raine Island for ~3–4 months during the nesting period (November–February). This was followed by direct movement (transit) to putative foraging grounds mostly in the Torres Straight where they switched to area-restricted search mode again, and remained resident for the remainder of the deployment (53–304 days). In contrast, tiger sharks displayed high spatial and temporal variation in movement behaviour which was not closely linked to the movement behaviour of green turtles or recognised turtle foraging grounds. On average, tiger sharks were concentrated around Raine Island throughout the year. While information on diet is required to determine whether tiger sharks are turtle specialists our results support the hypothesis that they target this predictable and plentiful prey during turtle nesting season, but they might not focus on this less predictable food source outside the nesting season.